-
1
-
-
0002656482
-
Hepatobiliary neoplasm
-
DeVita V.T., Hellmann S., and Rosenberg S.A. (Eds), Lippincott, Philadelphia, PA
-
Lotze M.T., Flickinger J.C., and Carr B.I. Hepatobiliary neoplasm. In: DeVita V.T., Hellmann S., and Rosenberg S.A. (Eds). Cancer: principles and practice of oncology. 4th ed (1993), Lippincott, Philadelphia, PA 883-887
-
(1993)
Cancer: principles and practice of oncology. 4th ed
, pp. 883-887
-
-
Lotze, M.T.1
Flickinger, J.C.2
Carr, B.I.3
-
2
-
-
0029939998
-
Telomere changes in human hepatocellular carcinomas and hepatitis virus infected noncancerous livers
-
Ohashi K., Tsutsumi M., Nakajima Y., Kobitsu K., Nakano H., and Konishi Y. Telomere changes in human hepatocellular carcinomas and hepatitis virus infected noncancerous livers. Cancer 77 (1996) 1747-1751
-
(1996)
Cancer
, vol.77
, pp. 1747-1751
-
-
Ohashi, K.1
Tsutsumi, M.2
Nakajima, Y.3
Kobitsu, K.4
Nakano, H.5
Konishi, Y.6
-
3
-
-
3042780966
-
Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatocellular carcinoma
-
Plentz R.R., Caselitz M., Bleck J.S., Gebel M., Flemming P., Kubicka S., Manns M.P., and Rudolph K.L. Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatocellular carcinoma. Hepatology 40 (2004) 80-86
-
(2004)
Hepatology
, vol.40
, pp. 80-86
-
-
Plentz, R.R.1
Caselitz, M.2
Bleck, J.S.3
Gebel, M.4
Flemming, P.5
Kubicka, S.6
Manns, M.P.7
Rudolph, K.L.8
-
4
-
-
24144488292
-
Telomere shortening correlates with increasing aneuploidy of chromosome 8 on a cellular level in primary human hepatocellular carcinoma
-
Plentz R.R., Schlegelberger B., Flemming P., Manns M.P., Rudolph K.L., and Wilkens L. Telomere shortening correlates with increasing aneuploidy of chromosome 8 on a cellular level in primary human hepatocellular carcinoma. Hepatology 42 (2005) 522-526
-
(2005)
Hepatology
, vol.42
, pp. 522-526
-
-
Plentz, R.R.1
Schlegelberger, B.2
Flemming, P.3
Manns, M.P.4
Rudolph, K.L.5
Wilkens, L.6
-
5
-
-
0036699940
-
Molecular pathogenesis of human hepatocellular carcinoma
-
Thorgeirsson S.S., and Grisham J.W. Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 31 (2002) 339-346
-
(2002)
Nat Genet
, vol.31
, pp. 339-346
-
-
Thorgeirsson, S.S.1
Grisham, J.W.2
-
6
-
-
0035950534
-
INK4a-ARF alterations and p53 mutations in hepatocellular carcinomas
-
Tannapfel A., Busse C., Weinans L., Benicke M., Katalinic A., Geissler F., Hauss J., and Wittekind C. INK4a-ARF alterations and p53 mutations in hepatocellular carcinomas. Oncogene 20 (2001) 7104-7109
-
(2001)
Oncogene
, vol.20
, pp. 7104-7109
-
-
Tannapfel, A.1
Busse, C.2
Weinans, L.3
Benicke, M.4
Katalinic, A.5
Geissler, F.6
Hauss, J.7
Wittekind, C.8
-
7
-
-
0038803997
-
Chromosomal instability and human hepatocarcinogenesis
-
Nishida N., Nishimura T., Ito T., Komeda T., Fukuda Y., and Nakao K. Chromosomal instability and human hepatocarcinogenesis. Histol Histopathol 18 (2003) 897-909
-
(2003)
Histol Histopathol
, vol.18
, pp. 897-909
-
-
Nishida, N.1
Nishimura, T.2
Ito, T.3
Komeda, T.4
Fukuda, Y.5
Nakao, K.6
-
8
-
-
2642580037
-
Analysis of DNA copy number aberrations in hepatitis C virus-associated hepatocellular carcinomas by conventional CGH and array CGH
-
Hashimoto K., Mori N., Tamesa T., Okada T., Kawauchi S., Oga A., Furuya T., Tangoku A., Oka M., and Sasaki K. Analysis of DNA copy number aberrations in hepatitis C virus-associated hepatocellular carcinomas by conventional CGH and array CGH. Mod Pathol 17 (2004) 617-622
-
(2004)
Mod Pathol
, vol.17
, pp. 617-622
-
-
Hashimoto, K.1
Mori, N.2
Tamesa, T.3
Okada, T.4
Kawauchi, S.5
Oga, A.6
Furuya, T.7
Tangoku, A.8
Oka, M.9
Sasaki, K.10
-
9
-
-
0842342605
-
Induction of aneuploidy by increasing chromosomal instability during dedifferentiation of hepatocellular carcinoma
-
Wilkens L., Flemming P., Gebel M., Bleck J., Terkamp C., Wingen L., Kreipe H., and Schlegelberger B. Induction of aneuploidy by increasing chromosomal instability during dedifferentiation of hepatocellular carcinoma. Proc Natl Acad Sci U S A 101 (2004) 1309-1314
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1309-1314
-
-
Wilkens, L.1
Flemming, P.2
Gebel, M.3
Bleck, J.4
Terkamp, C.5
Wingen, L.6
Kreipe, H.7
Schlegelberger, B.8
-
10
-
-
0000146723
-
Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse
-
Greenberg R.A., Chin L., Femino A., Lee K.H., Gottlieb G.J., Singer R.H., Greider C.W., and DePinho R.A. Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse. Cell 97 (1999) 515-525
-
(1999)
Cell
, vol.97
, pp. 515-525
-
-
Greenberg, R.A.1
Chin, L.2
Femino, A.3
Lee, K.H.4
Gottlieb, G.J.5
Singer, R.H.6
Greider, C.W.7
DePinho, R.A.8
-
11
-
-
0343228751
-
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
-
Gonzalez-Suarez E., Samper E., Flores J.M., and Blasco M.A. Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat Genet 26 (2000) 114-117
-
(2000)
Nat Genet
, vol.26
, pp. 114-117
-
-
Gonzalez-Suarez, E.1
Samper, E.2
Flores, J.M.3
Blasco, M.A.4
-
12
-
-
0034978564
-
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
-
Rudolph K.L., Millard M., Bosenberg M.W., and DePinho R.A. Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nat Genet 28 (2001) 155-159
-
(2001)
Nat Genet
, vol.28
, pp. 155-159
-
-
Rudolph, K.L.1
Millard, M.2
Bosenberg, M.W.3
DePinho, R.A.4
-
13
-
-
0042440603
-
Differential impact of telomere dysfunction on initiation and progression of hepatocellular carcinoma
-
Farazi P.A., Glickmann J., Jiang S., Yu A., Rudolph K.L., and DePinho R.A. Differential impact of telomere dysfunction on initiation and progression of hepatocellular carcinoma. Cancer Res 63 (2003) 5021-5027
-
(2003)
Cancer Res
, vol.63
, pp. 5021-5027
-
-
Farazi, P.A.1
Glickmann, J.2
Jiang, S.3
Yu, A.4
Rudolph, K.L.5
DePinho, R.A.6
-
14
-
-
0037224923
-
Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression
-
Chang S., Khoo C.M., Naylor M.L., Maser R.S., and DePinho R.A. Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression. Genes Dev 17 (2003) 88-100
-
(2003)
Genes Dev
, vol.17
, pp. 88-100
-
-
Chang, S.1
Khoo, C.M.2
Naylor, M.L.3
Maser, R.S.4
DePinho, R.A.5
-
15
-
-
0033525558
-
Longevity, stress response, and cancer in aging telomerase-deficient mice
-
Rudolph K.L., Chang S., Lee H.W., Blasco M., Gottlieb G.J., Greider C., and DePinho R.A. Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 96 (1999) 701-712
-
(1999)
Cell
, vol.96
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.W.3
Blasco, M.4
Gottlieb, G.J.5
Greider, C.6
DePinho, R.A.7
-
16
-
-
0034632717
-
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
-
Artandi S.E., Chang S., Lee S.L., Alson S., Gottlieb G.J., Chin L., and DePinho R.A. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 406 (2000) 641-645
-
(2000)
Nature
, vol.406
, pp. 641-645
-
-
Artandi, S.E.1
Chang, S.2
Lee, S.L.3
Alson, S.4
Gottlieb, G.J.5
Chin, L.6
DePinho, R.A.7
-
17
-
-
0033553516
-
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
-
Chin L., Artandi S.E., Shen Q., Tam A., Lee S.L., Gottlieb G.J., Greider C.W., and DePinho R.A. p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 97 (1999) 527-538
-
(1999)
Cell
, vol.97
, pp. 527-538
-
-
Chin, L.1
Artandi, S.E.2
Shen, Q.3
Tam, A.4
Lee, S.L.5
Gottlieb, G.J.6
Greider, C.W.7
DePinho, R.A.8
-
18
-
-
33646426898
-
Cooperative interactions of p53 mutation, telomere dysfunction and chronic liver damage in hepatocellular carcinoma progression
-
Farazi P.A., Glickman J., Horner J., and DePinho R.A. Cooperative interactions of p53 mutation, telomere dysfunction and chronic liver damage in hepatocellular carcinoma progression. Cancer Res 66 (2006) 4766-4773
-
(2006)
Cancer Res
, vol.66
, pp. 4766-4773
-
-
Farazi, P.A.1
Glickman, J.2
Horner, J.3
DePinho, R.A.4
-
19
-
-
0031054261
-
Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis
-
Miura N., Horikawa I., Nishimoto A., Ohmura H., Ito H., Hirohashi S., Shay J.W., and Oshimura M. Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis. Cancer Genet Cytogenet 93 (1997) 56-62
-
(1997)
Cancer Genet Cytogenet
, vol.93
, pp. 56-62
-
-
Miura, N.1
Horikawa, I.2
Nishimoto, A.3
Ohmura, H.4
Ito, H.5
Hirohashi, S.6
Shay, J.W.7
Oshimura, M.8
-
20
-
-
0034052368
-
Expression of telomerase component genes in hepatocellular carcinomas
-
Takahashi S., Kitamoto M., Takaishi H., Aikata H., Kawakami Y., Nakanishi T., Shimamoto F., Tahara E., Tahara H., Ide T., and Kajiyama G. Expression of telomerase component genes in hepatocellular carcinomas. Eur J Cancer 36 (2000) 496-502
-
(2000)
Eur J Cancer
, vol.36
, pp. 496-502
-
-
Takahashi, S.1
Kitamoto, M.2
Takaishi, H.3
Aikata, H.4
Kawakami, Y.5
Nakanishi, T.6
Shimamoto, F.7
Tahara, E.8
Tahara, H.9
Ide, T.10
Kajiyama, G.11
-
21
-
-
0026680249
-
The two-stage mechanism controlling cellular senescence and immortalization
-
Wright W.E., and Shay J.W. The two-stage mechanism controlling cellular senescence and immortalization. Exp Gerontol 27 (1992) 383-389
-
(1992)
Exp Gerontol
, vol.27
, pp. 383-389
-
-
Wright, W.E.1
Shay, J.W.2
-
22
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
Counter C.M., Avilion A.A., LeFeuvre C.E., Stewart N.G., Greider C.W., Harley C.B., and Bacchetti S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 11 (1992) 1921-1929
-
(1992)
EMBO J
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
Avilion, A.A.2
LeFeuvre, C.E.3
Stewart, N.G.4
Greider, C.W.5
Harley, C.B.6
Bacchetti, S.7
-
23
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
d'Adda di Fagagna F., Reaper P.M., Clay-Farrace L., Fiegler H., Carr P., Von Zglinicki T., Saretzki G., Carter N.P., and Jackson S.P. A DNA damage checkpoint response in telomere-initiated senescence. Nature 426 (2003) 194-198
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
d'Adda di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
Saretzki, G.7
Carter, N.P.8
Jackson, S.P.9
-
24
-
-
0028261160
-
Escape from senescence in human diploid fibroblasts induced directly by mutant p53
-
Bond J.A., Wyllie F.S., and Wynford-Thomas D. Escape from senescence in human diploid fibroblasts induced directly by mutant p53. Oncogene 9 (1994) 1885-1889
-
(1994)
Oncogene
, vol.9
, pp. 1885-1889
-
-
Bond, J.A.1
Wyllie, F.S.2
Wynford-Thomas, D.3
-
25
-
-
0035734285
-
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
-
Jonkers J., Meuwissen R., van der Gulden H., Peterse H., van der Valk M., and Berns A. Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat Genet 29 (2001) 418-425
-
(2001)
Nat Genet
, vol.29
, pp. 418-425
-
-
Jonkers, J.1
Meuwissen, R.2
van der Gulden, H.3
Peterse, H.4
van der Valk, M.5
Berns, A.6
-
26
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco M.A., Lee H.W., Hande M.P., Samper E., Lansdorp P.M., DePinho R.A., and Greider C.W. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91 (1997) 25-34
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
Samper, E.4
Lansdorp, P.M.5
DePinho, R.A.6
Greider, C.W.7
-
27
-
-
0024818649
-
Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice
-
Chisari F.V., Klopchin K., Moriyama T., Pasquinelli C., Dunsford H.A., Sell S., Pinkert C.A., Brinster R.L., and Palmiter R.D. Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell 59 (1989) 1145-1156
-
(1989)
Cell
, vol.59
, pp. 1145-1156
-
-
Chisari, F.V.1
Klopchin, K.2
Moriyama, T.3
Pasquinelli, C.4
Dunsford, H.A.5
Sell, S.6
Pinkert, C.A.7
Brinster, R.L.8
Palmiter, R.D.9
-
28
-
-
0035812845
-
The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
-
Hemann M.T., Strong M.A., Hao L.Y., and Greider C.W. The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 107 (2001) 67-77
-
(2001)
Cell
, vol.107
, pp. 67-77
-
-
Hemann, M.T.1
Strong, M.A.2
Hao, L.Y.3
Greider, C.W.4
-
29
-
-
0030845382
-
Cre-mediated somatic site-specific recombination in mice
-
Akagi K., Sandig V., Vooijs M., Van der Valk M., Giovannini M., Strauss M., and Berns A. Cre-mediated somatic site-specific recombination in mice. Nucleic Acids Res 25 (1997) 1766-1773
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 1766-1773
-
-
Akagi, K.1
Sandig, V.2
Vooijs, M.3
Van der Valk, M.4
Giovannini, M.5
Strauss, M.6
Berns, A.7
-
30
-
-
0030743347
-
Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP)
-
Kim N.W., and Wu F. Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP). Nucleic Acids Res 25 (1997) 2595-2597
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2595-2597
-
-
Kim, N.W.1
Wu, F.2
-
31
-
-
0033178240
-
Telomere length measurements using digital fluorescence microscopy
-
Poon S.S., Martens U.M., Ward R.K., and Lansdorp P.M. Telomere length measurements using digital fluorescence microscopy. Cytometry 36 (1999) 267-278
-
(1999)
Cytometry
, vol.36
, pp. 267-278
-
-
Poon, S.S.1
Martens, U.M.2
Ward, R.K.3
Lansdorp, P.M.4
-
32
-
-
9144262347
-
A whole-genome mouse BAC microarray with 1-Mb resolution for analysis of DNA copy number changes by array comparative genomic hybridization
-
Chung Y.J., Jonkers J., Kitson H., Fiegler H., Humphray S., Scott C., Hunt S., Yu Y., Nishijima I., Velds A., Holstege H., Carter N., and Bradley A. A whole-genome mouse BAC microarray with 1-Mb resolution for analysis of DNA copy number changes by array comparative genomic hybridization. Genome Res 14 (2004) 188-196
-
(2004)
Genome Res
, vol.14
, pp. 188-196
-
-
Chung, Y.J.1
Jonkers, J.2
Kitson, H.3
Fiegler, H.4
Humphray, S.5
Scott, C.6
Hunt, S.7
Yu, Y.8
Nishijima, I.9
Velds, A.10
Holstege, H.11
Carter, N.12
Bradley, A.13
-
33
-
-
0034616930
-
Functional discovery via a compendium of expression profiles
-
Hughes T.R., Marton M.J., Jones A.R., Roberts C.J., Stoughton R., Armour C.D., Bennett H.A., Coffey E., Dai H., He Y.D., Kidd M.J., King A.M., Meyer M.R., Slade D., Lum P.Y., Stepaniants S.B., Shoemaker D.D., Gachotte D., Chakraburtty K., Simon J., Bard M., and Friend S.H. Functional discovery via a compendium of expression profiles. Cell 102 (2000) 109-126
-
(2000)
Cell
, vol.102
, pp. 109-126
-
-
Hughes, T.R.1
Marton, M.J.2
Jones, A.R.3
Roberts, C.J.4
Stoughton, R.5
Armour, C.D.6
Bennett, H.A.7
Coffey, E.8
Dai, H.9
He, Y.D.10
Kidd, M.J.11
King, A.M.12
Meyer, M.R.13
Slade, D.14
Lum, P.Y.15
Stepaniants, S.B.16
Shoemaker, D.D.17
Gachotte, D.18
Chakraburtty, K.19
Simon, J.20
Bard, M.21
Friend, S.H.22
more..
-
35
-
-
14944374756
-
Contrasting effects of telomere shortening on organ homeostasis, tumor suppression, and survival during chronic liver damage
-
Wiemann S.U., Satyanarayana A., Buer J., Kamino K., Manns M.P., and Rudolph K.L. Contrasting effects of telomere shortening on organ homeostasis, tumor suppression, and survival during chronic liver damage. Oncogene 24 (2005) 1501-1509
-
(2005)
Oncogene
, vol.24
, pp. 1501-1509
-
-
Wiemann, S.U.1
Satyanarayana, A.2
Buer, J.3
Kamino, K.4
Manns, M.P.5
Rudolph, K.L.6
-
36
-
-
0001005091
-
Tumours of the liver
-
Tursov V., and Mohr U. (Eds), IARC, Lyon, France
-
Frith C.H., Wards J.M., and Turusoz V.S. Tumours of the liver. In: Tursov V., and Mohr U. (Eds). Pathology of tumours in laboratory animals, Vol. 2-tumours of the mouse (1994), IARC, Lyon, France 223-243
-
(1994)
Pathology of tumours in laboratory animals, Vol. 2-tumours of the mouse
, pp. 223-243
-
-
Frith, C.H.1
Wards, J.M.2
Turusoz, V.S.3
-
37
-
-
16244373665
-
Chromosome alterations in human hepatocellular carcinomas correlate with aetiology and histological grade--results of an explorative CGH meta-analysis
-
Moinzadeh P., Breuhahn K., Stutzer H., and Schirmacher P. Chromosome alterations in human hepatocellular carcinomas correlate with aetiology and histological grade--results of an explorative CGH meta-analysis. Br J Cancer 92 (2005) 935-941
-
(2005)
Br J Cancer
, vol.92
, pp. 935-941
-
-
Moinzadeh, P.1
Breuhahn, K.2
Stutzer, H.3
Schirmacher, P.4
-
38
-
-
0033616762
-
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
-
Zhu J., Wang H., Bishop J.M., and Blackburn E.H. Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening. Proc Natl Acad Sci U S A 96 (1999) 3723-3728
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3723-3728
-
-
Zhu, J.1
Wang, H.2
Bishop, J.M.3
Blackburn, E.H.4
-
39
-
-
20144389189
-
The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo
-
Lechel A., Satyanarayana A., Ju Z., Plentz R.R., Schaetzlein S., Rudolph C., Wilkens L., Wiemann S.U., Saretzki G., Malek N.P., Manns M.P., Buer J., and Rudolph K.L. The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo. EMBO Rep 6 (2005) 275-281
-
(2005)
EMBO Rep
, vol.6
, pp. 275-281
-
-
Lechel, A.1
Satyanarayana, A.2
Ju, Z.3
Plentz, R.R.4
Schaetzlein, S.5
Rudolph, C.6
Wilkens, L.7
Wiemann, S.U.8
Saretzki, G.9
Malek, N.P.10
Manns, M.P.11
Buer, J.12
Rudolph, K.L.13
|