-
1
-
-
0032925361
-
Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon-gamma
-
Ajizian S.J., English B.K., and Meals E.A. Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon-gamma. J. Infect. Dis. 179 (1999) 939-944
-
(1999)
J. Infect. Dis.
, vol.179
, pp. 939-944
-
-
Ajizian, S.J.1
English, B.K.2
Meals, E.A.3
-
2
-
-
0029126879
-
mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation
-
Chen C.Y., Xu N., and Shyu A.B. mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation. Mol. Cell. Biol. 15 (1995) 5777-5788
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5777-5788
-
-
Chen, C.Y.1
Xu, N.2
Shyu, A.B.3
-
4
-
-
0031771622
-
Stabilization of granulocyte-macrophage colony-stimulating factor RNA in a human eosinophil-like cell line requires the AUUUA motifs
-
Esnault S., Jarzembowski J.A., and Malter J.S. Stabilization of granulocyte-macrophage colony-stimulating factor RNA in a human eosinophil-like cell line requires the AUUUA motifs. Proc. Assoc. Am. Phys. 110 (1998) 575-584
-
(1998)
Proc. Assoc. Am. Phys.
, vol.110
, pp. 575-584
-
-
Esnault, S.1
Jarzembowski, J.A.2
Malter, J.S.3
-
5
-
-
21744442278
-
Tristetraprolin regulates the expression of the human inducible nitric-oxide synthase gene
-
Fechir M., Linker K., Pautz A., Hubrich T., Förstermann U., Rodriguez-Pascual F., and Kleinert H. Tristetraprolin regulates the expression of the human inducible nitric-oxide synthase gene. Mol. Pharmacol. 67 (2005) 2148-2161
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 2148-2161
-
-
Fechir, M.1
Linker, K.2
Pautz, A.3
Hubrich, T.4
Förstermann, U.5
Rodriguez-Pascual, F.6
Kleinert, H.7
-
6
-
-
0034698066
-
Glucocorticoid-mediated destabilization of cyclin D3 mRNA involves RNA-protein interactions in the 3'-untranslated region of the mRNA
-
Garcia-Gras E.A., Chi P., and Thompson E.A. Glucocorticoid-mediated destabilization of cyclin D3 mRNA involves RNA-protein interactions in the 3'-untranslated region of the mRNA. J. Biol. Chem. 275 (2000) 22001-22008
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 22001-22008
-
-
Garcia-Gras, E.A.1
Chi, P.2
Thompson, E.A.3
-
7
-
-
0038392886
-
Interplay between transcriptional and post-transcriptional regulation of Cyp2a5 expression
-
Glisovic T., Söderberg M., Christian K., Lang M., and Raffalli-Mathieu F. Interplay between transcriptional and post-transcriptional regulation of Cyp2a5 expression. Biochem. Pharmacol. 65 (2003) 1653-1661
-
(2003)
Biochem. Pharmacol.
, vol.65
, pp. 1653-1661
-
-
Glisovic, T.1
Söderberg, M.2
Christian, K.3
Lang, M.4
Raffalli-Mathieu, F.5
-
8
-
-
13844270512
-
Inhibition of tristetraprolin expression by dexamethasone in activated macrophages
-
Jalonen U., Lahti A., Korhonen R., Kankaanranta H., and Moilanen E. Inhibition of tristetraprolin expression by dexamethasone in activated macrophages. Biochem. Pharmacol. 69 (2005) 733-740
-
(2005)
Biochem. Pharmacol.
, vol.69
, pp. 733-740
-
-
Jalonen, U.1
Lahti, A.2
Korhonen, R.3
Kankaanranta, H.4
Moilanen, E.5
-
9
-
-
0034691522
-
Dexamethasone inhibits IL-1 beta gene expression in LPS-stimulated RAW 264.7 cells by blocking NF-kappa B/Rel and AP-1 activation
-
Jeon Y.J., Han S.H., Lee Y.W., Lee M., Yang K.H., and Kim H.M. Dexamethasone inhibits IL-1 beta gene expression in LPS-stimulated RAW 264.7 cells by blocking NF-kappa B/Rel and AP-1 activation. Immunopharmacology 48 (2000) 173-183
-
(2000)
Immunopharmacology
, vol.48
, pp. 173-183
-
-
Jeon, Y.J.1
Han, S.H.2
Lee, Y.W.3
Lee, M.4
Yang, K.H.5
Kim, H.M.6
-
10
-
-
1442333588
-
Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression
-
Kim S.H., Kim J., and Sharma R.P. Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression. Pharmacol. Res. 49 (2004) 433-439
-
(2004)
Pharmacol. Res.
, vol.49
, pp. 433-439
-
-
Kim, S.H.1
Kim, J.2
Sharma, R.P.3
-
11
-
-
0030060927
-
Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-kappa B
-
Kleinert H., Euchenhofer C., Ihrig-Biedert I., and Förstermann U. Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-kappa B. Mol. Pharmacol. 49 (1996) 15-21
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 15-21
-
-
Kleinert, H.1
Euchenhofer, C.2
Ihrig-Biedert, I.3
Förstermann, U.4
-
12
-
-
0036765329
-
Dexamethasone inhibits inducible nitric-oxide synthase expression and nitric oxide production by destabilizing mRNA in lipopolysaccharide-treated macrophages
-
Korhonen R., Lahti A., Hämäläinen M., Kankaanranta H., and Moilanen E. Dexamethasone inhibits inducible nitric-oxide synthase expression and nitric oxide production by destabilizing mRNA in lipopolysaccharide-treated macrophages. Mol. Pharmacol. 62 (2002) 698-704
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 698-704
-
-
Korhonen, R.1
Lahti, A.2
Hämäläinen, M.3
Kankaanranta, H.4
Moilanen, E.5
-
13
-
-
0030070297
-
Molecular mechanisms of dexamethasone inhibition of nitric oxide synthase expression in interleukin 1 beta-stimulated mesangial cells: evidence for the involvement of transcriptional and posttranscriptional regulation
-
Kunz D., Walker G., Eberhardt W., and Pfeilschifter J. Molecular mechanisms of dexamethasone inhibition of nitric oxide synthase expression in interleukin 1 beta-stimulated mesangial cells: evidence for the involvement of transcriptional and posttranscriptional regulation. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 255-259
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 255-259
-
-
Kunz, D.1
Walker, G.2
Eberhardt, W.3
Pfeilschifter, J.4
-
14
-
-
0042844654
-
c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages
-
Lahti A., Jalonen U., Kankaanranta H., and Moilanen E. c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages. Mol. Pharmacol. 64 (2003) 308-315
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 308-315
-
-
Lahti, A.1
Jalonen, U.2
Kankaanranta, H.3
Moilanen, E.4
-
15
-
-
0035138742
-
Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38
-
Lasa M., Brook M., Saklatvala J., and Clark A.R. Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38. Mol. Cell. Biol. 21 (2001) 771-780
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 771-780
-
-
Lasa, M.1
Brook, M.2
Saklatvala, J.3
Clark, A.R.4
-
16
-
-
0036841288
-
Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38
-
Lasa M., Abraham S.M., Boucheron C., Saklatvala J., and Clark A.R. Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38. Mol. Cell. Biol. 22 (2002) 7802-7811
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7802-7811
-
-
Lasa, M.1
Abraham, S.M.2
Boucheron, C.3
Saklatvala, J.4
Clark, A.R.5
-
17
-
-
24144499990
-
Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR
-
Linker K., Pautz A., Fechir M., Hubrich T., Greeve J., and Kleinert H. Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR. Nucleic Acids Res. 33 (2005) 4813-4827
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 4813-4827
-
-
Linker, K.1
Pautz, A.2
Fechir, M.3
Hubrich, T.4
Greeve, J.5
Kleinert, H.6
-
19
-
-
10144224274
-
Nitric oxide synthase type II mRNA stability is translation- and transcription-dependent
-
Park S.K., and Murphy S. Nitric oxide synthase type II mRNA stability is translation- and transcription-dependent. J. Neurochem. 67 (1996) 1766-1769
-
(1996)
J. Neurochem.
, vol.67
, pp. 1766-1769
-
-
Park, S.K.1
Murphy, S.2
-
20
-
-
0026100340
-
The AU-rich sequences in the 3' untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids
-
Peppel K., Vinci J.M., and Baglioni C. The AU-rich sequences in the 3' untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids. J. Exp. Med. 173 (1991) 349-355
-
(1991)
J. Exp. Med.
, vol.173
, pp. 349-355
-
-
Peppel, K.1
Vinci, J.M.2
Baglioni, C.3
-
21
-
-
0025672648
-
Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells
-
Radomski M.W., Palmer R.M., and Moncada S. Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 10043-10047
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 10043-10047
-
-
Radomski, M.W.1
Palmer, R.M.2
Moncada, S.3
-
22
-
-
0028107237
-
Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor
-
Ray A., and Prefontaine K.E. Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. Proc. Natl. Acad. Sci. U. S.A. 91 (1994) 752-756
-
(1994)
Proc. Natl. Acad. Sci. U. S.A.
, vol.91
, pp. 752-756
-
-
Ray, A.1
Prefontaine, K.E.2
-
23
-
-
0029809863
-
Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: evidence for post-transcriptional regulation
-
Ristimäki A., Narko K., and Hla T. Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: evidence for post-transcriptional regulation. Biochem. J. 318 Pt. 1 (1996) 325-331
-
(1996)
Biochem. J.
, vol.318
, Issue.PART 1
, pp. 325-331
-
-
Ristimäki, A.1
Narko, K.2
Hla, T.3
-
24
-
-
0034714259
-
Complex contribution of the 3'-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR.
-
Rodriguez-Pascual F., Hausding M., Ihrig-Biedert I., Furneaux H., Levy A.P., Förstermann U., and Kleinert H. Complex contribution of the 3'-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR. J. Biol. Chem. 275 (2000) 26040-26049
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26040-26049
-
-
Rodriguez-Pascual, F.1
Hausding, M.2
Ihrig-Biedert, I.3
Furneaux, H.4
Levy, A.P.5
Förstermann, U.6
Kleinert, H.7
-
25
-
-
0031888836
-
Involvement of transcriptional mechanisms in the inhibition of NOS2 expression by dexamethasone in rat mesangial cells
-
Saura M., Zaragoza C., Diaz-Cazorla M., Hernandez-Perera O., Eng E., Lowenstein C.J., Perez-Sala D., and Lamas S. Involvement of transcriptional mechanisms in the inhibition of NOS2 expression by dexamethasone in rat mesangial cells. Kidney Int. 53 (1998) 38-49
-
(1998)
Kidney Int.
, vol.53
, pp. 38-49
-
-
Saura, M.1
Zaragoza, C.2
Diaz-Cazorla, M.3
Hernandez-Perera, O.4
Eng, E.5
Lowenstein, C.J.6
Perez-Sala, D.7
Lamas, S.8
-
26
-
-
0028879819
-
Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids
-
Scheinman R.I., Cogswell P.C., Lofquist A.K., and Baldwin Jr. A.S. Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 270 (1995) 283-286
-
(1995)
Science
, vol.270
, pp. 283-286
-
-
Scheinman, R.I.1
Cogswell, P.C.2
Lofquist, A.K.3
Baldwin Jr., A.S.4
-
28
-
-
0028787096
-
Effect of transcription inhibitors on the iron-dependent degradation of transferrin receptor mRNA
-
Seiser C., Posch M., Thompson N., and Kuhn L.C. Effect of transcription inhibitors on the iron-dependent degradation of transferrin receptor mRNA. J. Biol. Chem. 270 (1995) 29400-29406
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29400-29406
-
-
Seiser, C.1
Posch, M.2
Thompson, N.3
Kuhn, L.C.4
-
29
-
-
0036070957
-
Inflammation modulates the interaction of heterogeneous nuclear ribonucleoprotein (hnRNP) I/polypyrimidine tract binding protein and hnRNP L with the 3'untranslated region of the murine inducible nitric-oxide synthase mRNA
-
Söderberg M., Raffalli-Mathieu F., and Lang M.A. Inflammation modulates the interaction of heterogeneous nuclear ribonucleoprotein (hnRNP) I/polypyrimidine tract binding protein and hnRNP L with the 3'untranslated region of the murine inducible nitric-oxide synthase mRNA. Mol. Pharmacol. 62 (2002) 423-431
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 423-431
-
-
Söderberg, M.1
Raffalli-Mathieu, F.2
Lang, M.A.3
-
30
-
-
33747868143
-
Identification of a regulatory cis-element within the 3'untranslated region of the murine inducible nitric-oxide synthase (iNOS) mRNA: interaction with heterogeneous nuclear ribonucleoproteins I and L and role in the iNOS gene expression
-
(Epub 2006)
-
Söderberg M., Raffalli-Mathieu F., and Lang M.A. Identification of a regulatory cis-element within the 3'untranslated region of the murine inducible nitric-oxide synthase (iNOS) mRNA: interaction with heterogeneous nuclear ribonucleoproteins I and L and role in the iNOS gene expression. Mol. Immunol. 44 (2007) 434-442 (Epub 2006)
-
(2007)
Mol. Immunol.
, vol.44
, pp. 434-442
-
-
Söderberg, M.1
Raffalli-Mathieu, F.2
Lang, M.A.3
-
31
-
-
0027203305
-
Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta
-
Vodovotz Y., Bogdan C., Paik J., Xie Q.W., and Nathan C. Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta. J. Exp. Med. 178 (1993) 605-613
-
(1993)
J. Exp. Med.
, vol.178
, pp. 605-613
-
-
Vodovotz, Y.1
Bogdan, C.2
Paik, J.3
Xie, Q.W.4
Nathan, C.5
-
32
-
-
0030960334
-
Mechanisms of suppression of inducible nitric-oxide synthase (iNOS) expression in interferon (IFN)-gamma-stimulated RAW 264.7 cells by dexamethasone. Evidence for glucocorticoid-induced degradation of iNOS protein by calpain as a key step in post-transcriptional regulation
-
Walker G., Pfeilschifter J., and Kunz D. Mechanisms of suppression of inducible nitric-oxide synthase (iNOS) expression in interferon (IFN)-gamma-stimulated RAW 264.7 cells by dexamethasone. Evidence for glucocorticoid-induced degradation of iNOS protein by calpain as a key step in post-transcriptional regulation. J. Biol. Chem. 272 (1997) 16679-16687
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16679-16687
-
-
Walker, G.1
Pfeilschifter, J.2
Kunz, D.3
-
33
-
-
0028206469
-
Dual mechanism for the control of inducible-type NO synthase gene expression in macrophages during activation by interferon-gamma and bacterial lipopolysaccharide. Transcriptional and post-transcriptional regulation
-
Weisz A., Oguchi S., Cicatiello L., and Esumi H. Dual mechanism for the control of inducible-type NO synthase gene expression in macrophages during activation by interferon-gamma and bacterial lipopolysaccharide. Transcriptional and post-transcriptional regulation. J. Biol. Chem. 269 (1994) 8324-8333
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 8324-8333
-
-
Weisz, A.1
Oguchi, S.2
Cicatiello, L.3
Esumi, H.4
|