Predicting DNA-binding amino acid residues from electrostatic stabilization upon mutation to Asp/Glu and evolutionary conservation

Proteins: Structure, Function and Genetics

Volumn 67, Issue 3, 2007, Pages 671-680

  Yao, Chi Chen ^a   Chih, Yuan Wu ^a   Lim, Carmay ^a,b  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

DNA binding proteins; Functional annotation; Protein functional sites; Protein DNA interaction

Indexed keywords

AMINO ACID; ASPARTIC ACID; DNA BINDING PROTEIN; DOUBLE STRANDED DNA; GLUTAMIC ACID; MUTANT PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DNA BINDING MOTIF; ELECTRICITY; GENETIC CONSERVATION; PREDICTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DNA BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURAL PROTEOMICS; STRUCTURE ACTIVITY RELATION;

AMINO ACIDS; ASPARTIC ACID; BINDING SITES; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; DATABASES, PROTEIN; DNA-BINDING PROTEINS; ELECTROSTATICS; EVOLUTION, MOLECULAR; GLUTAMIC ACID; MODELS, MOLECULAR; MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34247250713     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21366     Document Type: Article

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