Exploiting the regioselectivity of pyroglutamate alkylations for the synthesis of 6-azabicyclo[3.2.1]octanes and 4-azabicyclo[3.3.0]octanes

Tetrahedron

Volumn 63, Issue 22, 2007, Pages 4712-4724

  Masschelein, Kurt G R ^a   Stevens, Christian V ^a   Dieltiens, Nicolai ^a   Claeys, Diederica D ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

4 AZABICYCLO[3.3.0]OCTANE DERIVATIVE; 5 BENZYL 1,6 DI TERT BUTYL 3 METHYLENE 7 OXO 6 AZABICYCLO[3.2.1]OCTANE 1,5,6 TRICARBOXYLATE; 5 ETHYL 6 (TERT BUTYL) 3 METHYLENE 7 OXO 6 AZABICYCLO[3.2.1]OCTANE 5,6 DICARBOXYLATE; 5 ETHYL 6 (TERT BUTYL) 3,7 DIOXO 6 AZABICYCLO[3.2.1]OCTANE 5,6 DICARBOXYLATE; 6 AZABICYCLO[3.2.1]OCTANE DERIVATIVE; 6 BENZYL 1 (2 CHLOROMETHYLALLYL) N,N DIALLYL 3 METHYLENE 7 OXO 6 AZABICYCLO[3.2.1]OCTANE 6 CARBOXAMIDE; 6 BENZYL 3 METHYLENE 7 OXO 6 AZABICYCLO[3.2.1]OCTANE 5 CARBOXYLATE; BENZYL 6 BENZYL 3 METHYLENE 7 OXO 6 AZABICYCLO[3.2.1]OCTANE 5 CARBOXYLATE; BICYCLO COMPOUND; METHYL 7 BENZYL 3,4 DIMETHYLENE 8 OXO 7 AZABICYCLO[4.2.1]NONANE 6 CARBOXYLATE; OCTANE; PYROGLUTAMIC ACID; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CHIRALITY; CONFORMATION; CYCLIZATION; PRIORITY JOURNAL; RING CLOSING METATHESIS; STEREOCHEMISTRY; SYNTHESIS;

EID: 34247232553     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2007.03.084     Document Type: Article

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