-
1
-
-
0018190794
-
Activity of flumequine against. Escherichia coli: In vitro comparison with nalidixic and oxolinic acids
-
Greenwood D. Activity of flumequine against. Escherichia coli: in vitro comparison with nalidixic and oxolinic acids. Antimicrob Agents Chemother. 13: 479-483. 1978.
-
(1978)
Antimicrob Agents Chemother
, vol.13
, pp. 479-483
-
-
Greenwood, D.1
-
2
-
-
16544384764
-
-
JECFA Evaluation of certain veterinary drug residues in food. Sixty-second report of the Joint FAO/WHO Expert Committee on food additives. World Health Organ. Tech Rep Ser. 925: 18-19. 2004.
-
JECFA Evaluation of certain veterinary drug residues in food. Sixty-second report of the Joint FAO/WHO Expert Committee on food additives. World Health Organ. Tech Rep Ser. 925: 18-19. 2004.
-
-
-
-
3
-
-
34247261277
-
-
JECFA Evaluation of certain veterinary drug residues in food. Forty-eighth report of the Joint FAO/WHO Expert Committee on food additives. World Health Organ. Tech Rep Ser. 879: 35-43. 1998.
-
JECFA Evaluation of certain veterinary drug residues in food. Forty-eighth report of the Joint FAO/WHO Expert Committee on food additives. World Health Organ. Tech Rep Ser. 879: 35-43. 1998.
-
-
-
-
4
-
-
0033017830
-
Hepatotoxicity and consequently increased cell proliferation are associated with flumequine hepatocarcinogenesis in mice
-
Yoshida M, Miyajima K, Shiraki K, Ando J, Kudoh K, Nakae D, Takahashi M, and Maekawa A. Hepatotoxicity and consequently increased cell proliferation are associated with flumequine hepatocarcinogenesis in mice. Cancer Lett. 141: 99-107. 1999.
-
(1999)
Cancer Lett
, vol.141
, pp. 99-107
-
-
Yoshida, M.1
Miyajima, K.2
Shiraki, K.3
Ando, J.4
Kudoh, K.5
Nakae, D.6
Takahashi, M.7
Maekawa, A.8
-
5
-
-
0036772742
-
Mechanistic study on flumequine hepatocarcinogenecity focusing on DNA damage in mice
-
Kashida Y, Sasaki YF, Ohsawa K, Yokohama A, Watanabe T, and Mitsumori K. Mechanistic study on flumequine hepatocarcinogenecity focusing on DNA damage in mice. Toxicol Sci. 69: 317-321. 2002.
-
(2002)
Toxicol Sci
, vol.69
, pp. 317-321
-
-
Kashida, Y.1
Sasaki, Y.F.2
Ohsawa, K.3
Yokohama, A.4
Watanabe, T.5
Mitsumori, K.6
-
6
-
-
0005017897
-
Modifying effects of flumequine on dimethylnitrosamine-induced hepatocarcinogenesis in heterozygous p53 deficient CBA mice
-
Takizawa T, Mitsumori K, Takagi H, Onodera H, Yasuhara K, Tamura T, and Hirose M. Modifying effects of flumequine on dimethylnitrosamine-induced hepatocarcinogenesis in heterozygous p53 deficient CBA mice. J Toxicol Pathol. 14: 135-143. 2001.
-
(2001)
J Toxicol Pathol
, vol.14
, pp. 135-143
-
-
Takizawa, T.1
Mitsumori, K.2
Takagi, H.3
Onodera, H.4
Yasuhara, K.5
Tamura, T.6
Hirose, M.7
-
7
-
-
33745631509
-
Gene expression analysis in mice liver on hepatocarcinogenesis by flumequine
-
Kashida Y, Takahashi A, Moto M, Okamura M, Muguruma M, Jin M, Arai K, and Mitsumori K. Gene expression analysis in mice liver on hepatocarcinogenesis by flumequine. Arch Toxicol. 80: 533-539. 2006.
-
(2006)
Arch Toxicol
, vol.80
, pp. 533-539
-
-
Kashida, Y.1
Takahashi, A.2
Moto, M.3
Okamura, M.4
Muguruma, M.5
Jin, M.6
Arai, K.7
Mitsumori, K.8
-
8
-
-
33846299897
-
Lack of in vivo mutagenicity and oxidative DNA damage by flumequine in the livers of gpt delta mice
-
Kuroiwa Y, Umemura T, Nishikawa A, Kanki K, Ishii Y, Kodama Y, Masumura KI, Nohmi T, and Hirose M. Lack of in vivo mutagenicity and oxidative DNA damage by flumequine in the livers of gpt delta mice. Arch Toxicol. 81: 63-69. 2007.
-
(2007)
Arch Toxicol
, vol.81
, pp. 63-69
-
-
Kuroiwa, Y.1
Umemura, T.2
Nishikawa, A.3
Kanki, K.4
Ishii, Y.5
Kodama, Y.6
Masumura, K.I.7
Nohmi, T.8
Hirose, M.9
-
9
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ and Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 25: 402-408, 2001.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
10
-
-
0018187696
-
Gamma-glutamyltransferase in putative premalignant liver cell populations during hepatocarcinogenesis
-
Cameron R, Kellen J, Kolin A, Malkin A, and Farber E. Gamma-glutamyltransferase in putative premalignant liver cell populations during hepatocarcinogenesis. Cancer Res. 38: 823-829. 1978.
-
(1978)
Cancer Res
, vol.38
, pp. 823-829
-
-
Cameron, R.1
Kellen, J.2
Kolin, A.3
Malkin, A.4
Farber, E.5
-
11
-
-
20144372038
-
Enzymatic detection of precursor cell populations of preneoplastic foci positive for gamma-glutamyltranspeptidase in rat liver
-
Satoh K, Takahashi G, Miura T, Hayakari M, and Hatayama I. Enzymatic detection of precursor cell populations of preneoplastic foci positive for gamma-glutamyltranspeptidase in rat liver. Int J Cancer. 115: 711-716. 2005.
-
(2005)
Int J Cancer
, vol.115
, pp. 711-716
-
-
Satoh, K.1
Takahashi, G.2
Miura, T.3
Hayakari, M.4
Hatayama, I.5
-
12
-
-
15744390110
-
Contribution of mitochondrial DNA repair to cell resistance from oxidative stress
-
Grishko VI, Rachel LI, Spitz DR, Wilson GL, and LeDoux SP. Contribution of mitochondrial DNA repair to cell resistance from oxidative stress. J Biol Chem. 280: 8901-8905. 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 8901-8905
-
-
Grishko, V.I.1
Rachel, L.I.2
Spitz, D.R.3
Wilson, G.L.4
LeDoux, S.P.5
-
13
-
-
0020188453
-
Oxidase and oxygenase function of the microsomal cytochrome P450 monooxygenase system
-
Kuthan H and Ulrich V. Oxidase and oxygenase function of the microsomal cytochrome P450 monooxygenase system. Eur J Biochem. 126: 583-588. 1982.
-
(1982)
Eur J Biochem
, vol.126
, pp. 583-588
-
-
Kuthan, H.1
Ulrich, V.2
-
14
-
-
0025087596
-
Sensitive and rapid quantitation of oxygen reactive species formation in rat synaptosomes
-
LeBel CP and Bondy SC. Sensitive and rapid quantitation of oxygen reactive species formation in rat synaptosomes. Neurochem. Int. 17: 435-440. 1990.
-
(1990)
Neurochem. Int
, vol.17
, pp. 435-440
-
-
LeBel, C.P.1
Bondy, S.C.2
-
15
-
-
33748703427
-
Possible involvement of oxidative stress in dicyclanil-induced hepatocarcinogenesis in mice
-
Moto M, Umemura T, Okamura M, Muguruma M, Ito T, Jin M, Kashida Y, and Mitsumori K. Possible involvement of oxidative stress in dicyclanil-induced hepatocarcinogenesis in mice. Arch Toxicol. 80: 694-702. 2006.
-
(2006)
Arch Toxicol
, vol.80
, pp. 694-702
-
-
Moto, M.1
Umemura, T.2
Okamura, M.3
Muguruma, M.4
Ito, T.5
Jin, M.6
Kashida, Y.7
Mitsumori, K.8
-
16
-
-
33750711768
-
Molecular pathological analysis for determining the possible mechanism of piperonyl butoxide-induced hepatocarcinogenesis in mice
-
Muguruma M, Nishimura J, Jin M, Kashida Y, Moto M, Takahashi M, Yokouchi Y, and Mitsumori K. Molecular pathological analysis for determining the possible mechanism of piperonyl butoxide-induced hepatocarcinogenesis in mice. Toxicology. 228: 178-187. 2006.
-
(2006)
Toxicology
, vol.228
, pp. 178-187
-
-
Muguruma, M.1
Nishimura, J.2
Jin, M.3
Kashida, Y.4
Moto, M.5
Takahashi, M.6
Yokouchi, Y.7
Mitsumori, K.8
-
17
-
-
0030474051
-
Thiol regulation of endotoxin-induced release of tumour necrosis factor alpha from isolated rat Kupffer cells
-
Neuschwander-Tetri BA, Bellezzo JM, Britton RS, Bacon BR, and Fox ES. Thiol regulation of endotoxin-induced release of tumour necrosis factor alpha from isolated rat Kupffer cells. Biochem. J. 320: 1005-1010. 1996.
-
(1996)
Biochem. J
, vol.320
, pp. 1005-1010
-
-
Neuschwander-Tetri, B.A.1
Bellezzo, J.M.2
Britton, R.S.3
Bacon, B.R.4
Fox, E.S.5
-
18
-
-
0037763721
-
Regulatory mechanisms controlling gene expression mediated by the antioxidant response element
-
Nguyen T, Sherrat PJ, and Pickett CB. Regulatory mechanisms controlling gene expression mediated by the antioxidant response element. Annu Rev Pharmacol Toxicol. 43: 233-260. 2003.
-
(2003)
Annu Rev Pharmacol Toxicol
, vol.43
, pp. 233-260
-
-
Nguyen, T.1
Sherrat, P.J.2
Pickett, C.B.3
-
19
-
-
0029561598
-
The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
-
Hayes JD and Pulford DJ. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol. 30: 445-600. 1995.
-
(1995)
Crit Rev Biochem Mol Biol
, vol.30
, pp. 445-600
-
-
Hayes, J.D.1
Pulford, D.J.2
-
20
-
-
0023506857
-
The effects of selenium and copper deficiencies on glutathione S-transferase and glutathione peroxidase in rat liver
-
Arthur JR, Morrice PC, Nicol F, Beddows SE, Boyd R, Hayes JD, and Beckett GJ. The effects of selenium and copper deficiencies on glutathione S-transferase and glutathione peroxidase in rat liver. Biochem. J. 248: 539-544. 1987.
-
(1987)
Biochem. J
, vol.248
, pp. 539-544
-
-
Arthur, J.R.1
Morrice, P.C.2
Nicol, F.3
Beddows, S.E.4
Boyd, R.5
Hayes, J.D.6
Beckett, G.J.7
-
21
-
-
0028171293
-
-
2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response. Cell. 79: 583-593. 1994.
-
2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response. Cell. 79: 583-593. 1994.
-
-
-
-
22
-
-
0036840585
-
Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress
-
Kang KW, Lee SJ, Park JW, and Kim SG., Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress. Mol Pharmacol. 62: 1001-1010. 2002.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 1001-1010
-
-
Kang, K.W.1
Lee, S.J.2
Park, J.W.3
Kim, S.G.4
-
23
-
-
5444240961
-
Contribution of NAD(P)H:quinone oxidoreductase 1 to protection against carcinogenesis, and regulation of its gene by the Nrf2 basic-region leucine zipper and the arylhydrocarbon receptor basic helix-loop-helix transcription factors
-
Nioi P and Hayes JD. Contribution of NAD(P)H:quinone oxidoreductase 1 to protection against carcinogenesis, and regulation of its gene by the Nrf2 basic-region leucine zipper and the arylhydrocarbon receptor basic helix-loop-helix transcription factors. Mutat Res. 555: 149-171. 2004.
-
(2004)
Mutat Res
, vol.555
, pp. 149-171
-
-
Nioi, P.1
Hayes, J.D.2
-
24
-
-
0033655446
-
Regulation of glutathione synthesis
-
Lu SC. Regulation of glutathione synthesis. Curr Top Cell Regul. 36: 95-116. 2000.
-
(2000)
Curr Top Cell Regul
, vol.36
, pp. 95-116
-
-
Lu, S.C.1
-
26
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, and Yamamoto M. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 13: 76-86. 1999.
-
(1999)
Genes Dev
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
27
-
-
0036708902
-
Antioxidants and oxidants regulated signal transduction pathways
-
Owuor ED and Kong AN. Antioxidants and oxidants regulated signal transduction pathways. Biochem Pharmacol. 64: 765-770. 2002.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 765-770
-
-
Owuor, E.D.1
Kong, A.N.2
-
28
-
-
33747377165
-
c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity
-
Stepniak E, Ricci R, Eferl R, Sumara G, Sumara I, Rath M, Hui L, and Wagner EF. c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity. Genes Dev. 20: 2306-2314. 2006.
-
(2006)
Genes Dev
, vol.20
, pp. 2306-2314
-
-
Stepniak, E.1
Ricci, R.2
Eferl, R.3
Sumara, G.4
Sumara, I.5
Rath, M.6
Hui, L.7
Wagner, E.F.8
-
29
-
-
0026812207
-
2+] in induction of c-fos, c-jun, and c-myc mRNA in rat PTE after oxidative stress
-
2+] in induction of c-fos, c-jun, and c-myc mRNA in rat PTE after oxidative stress. FASEB J. 6: 919-924. 1992.
-
(1992)
FASEB J
, vol.6
, pp. 919-924
-
-
Maki, A.1
Berezesky, I.K.2
Fargnoli, J.3
Holbrook, N.J.4
Trump, B.F.5
-
30
-
-
0034213842
-
Nrf2 and c-Jun regulation of antioxidant response element (ARE)-mediated expression and induction of gamma-glutamylcysteine synthetase heavy subunit gene
-
Jeyapaul J and Jaiswal AK. Nrf2 and c-Jun regulation of antioxidant response element (ARE)-mediated expression and induction of gamma-glutamylcysteine synthetase heavy subunit gene. Biochem Pharmacol. 59: 1433-1439. 2000.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 1433-1439
-
-
Jeyapaul, J.1
Jaiswal, A.K.2
-
31
-
-
0032542213
-
Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes
-
Venugopal R and Jaiswal AK. Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes. Oncogene. 17: 3145-3156. 1998.
-
(1998)
Oncogene
, vol.17
, pp. 3145-3156
-
-
Venugopal, R.1
Jaiswal, A.K.2
-
32
-
-
0029906134
-
Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene
-
Venugopal R and Jaiswal AK. Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene. Proc Natl Acad Sci USA. 93: 14960-14965. 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14960-14965
-
-
Venugopal, R.1
Jaiswal, A.K.2
-
33
-
-
33644501791
-
Activation of the Nrf2-ARE signaling pathway: A promising strategy in cancer prevention
-
Giudice A, and Montella M. Activation of the Nrf2-ARE signaling pathway: a promising strategy in cancer prevention. Bioessays. 28: 169-181. 2006.
-
(2006)
Bioessays
, vol.28
, pp. 169-181
-
-
Giudice, A.1
Montella, M.2
-
34
-
-
32444433202
-
Free radicals, metals and antioxidants in oxidative stress-induced cancer
-
Valko M, Rhodes CJ, Moncol J, Izakovic M, and Mazur M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact. 160: 1-40. 2006.
-
(2006)
Chem Biol Interact
, vol.160
, pp. 1-40
-
-
Valko, M.1
Rhodes, C.J.2
Moncol, J.3
Izakovic, M.4
Mazur, M.5
-
35
-
-
0034190272
-
Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis
-
Hsu TC, Young MR, Cmarik J, and Colburn NH. Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis. Free Radic Biol Med. 28: 1338-1348. 2000.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 1338-1348
-
-
Hsu, T.C.1
Young, M.R.2
Cmarik, J.3
Colburn, N.H.4
-
36
-
-
0025806587
-
Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain
-
Binetruy B, Smeal T, Karin M. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. Nature. 351: 122-127. 1991.
-
(1991)
Nature
, vol.351
, pp. 122-127
-
-
Binetruy, B.1
Smeal, T.2
Karin, M.3
-
37
-
-
0025788098
-
Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
-
Smeal T, Binetruy B, Mercola DA, Birrer M, and Karin M. Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature. 354: 494-496. 1991.
-
(1991)
Nature
, vol.354
, pp. 494-496
-
-
Smeal, T.1
Binetruy, B.2
Mercola, D.A.3
Birrer, M.4
Karin, M.5
-
38
-
-
0025973702
-
Assays for 8-hydroxy-2′-deoxyguanosine: A biomarker of in vivo oxidative DNA damage
-
Shigenaga MK and Ames BN. Assays for 8-hydroxy-2′-deoxyguanosine: a biomarker of in vivo oxidative DNA damage. Free Radic Biol Med. 10: 211-216. 1991.
-
(1991)
Free Radic Biol Med
, vol.10
, pp. 211-216
-
-
Shigenaga, M.K.1
Ames, B.N.2
-
39
-
-
0242643763
-
DNA adduct formation and oxidative stress in colon and liver of Big Blue rats after dietary exposure to diesel particles
-
Dybdahl M, Risom L, Moller P, Autrup H, Wallin H, Vogel U, Bornholdt J, Daneshvar B, Dragsted LO, Weimann A, Poulsen HE, and Loft S. DNA adduct formation and oxidative stress in colon and liver of Big Blue rats after dietary exposure to diesel particles. Carcinogenesis. 24: 1759-1766. 2003.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1759-1766
-
-
Dybdahl, M.1
Risom, L.2
Moller, P.3
Autrup, H.4
Wallin, H.5
Vogel, U.6
Bornholdt, J.7
Daneshvar, B.8
Dragsted, L.O.9
Weimann, A.10
Poulsen, H.E.11
Loft, S.12
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