Roles of angiopoietin-1 and angiopoietin-2 on airway microvascular permeability in asthmatic patients

Chest

Volumn 131, Issue 4, 2007, Pages 1035-1041

  Kanazawa, Hiroshi ^a   Nomura, Saeko ^a   Asai, Kazuhisa ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Airway remodeling; Bronchial asthma; Vascular endothelial growth factor

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; EOSINOPHIL CATIONIC PROTEIN; FLUTICASONE PROPIONATE; METHACHOLINE; MONTELUKAST; NITRIC OXIDE; VASCULOTROPIN;

ADULT; ARTICLE; ASTHMA; BLOOD VESSEL PERMEABILITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EOSINOPHIL; EXPIRED AIR; FEMALE; HUMAN; MALE; MICROVASCULATURE; PRIORITY JOURNAL; PROVOCATION TEST; RANDOMIZED CONTROLLED TRIAL; SPUTUM ANALYSIS; STATISTICAL ANALYSIS; VOLUNTEER;

EID: 34247218175     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.06-2758     Document Type: Article

References (39)

1. Jeffery PK. Remodeling in asthma and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001; 164: S28-S38
2. Li X, Wilson JW. Increased vascularity of the bronchial mucosa in mild asthma. Am J Respir Crit Care Med 1997; 156:229-233
3. Bai TR, Cooper J, Koelmeyer T, et al. The effect of age and duration of disease on airway structure in fatal asthma. Am J Respir Crit Care Med 2000; 162:663-669
4. Niimi A, Matsumoto H, Amitani R, et al. Airway wall thickness in asthma assessed by computed tomography: relation to clinical indices. Am J Respir Crit Care Med 2000; 162:1518-1523
5. Salvato G. Quantitative and morphological analysis of the vascular bed in bronchial biopsy specimens from asthmatic and non-asthmatic subjects. Thorax 2001; 56:902-906
6. Kanazawa H, Asai K, Hirata K, et al. Vascular involvement in exercise-induced airway narrowing in patients with bronchial asthma. Chest 2002; 122:166-170
7. Kanazawa H, Hirata K, Yoshikawa J. Involvement of vascular endothelial growth factor in exercise induced bronchoconstriction in asthmatic patients. Thorax 2002; 57:885-888
8. Maniscalco WM, Watldns RH, D'Angio CT, et al. Hyperoxic injury decreases alveolar epithelial cell expression of vascular endodielial growth factor (VEGF) in neonatal rabbit lung. Am J Respir Cell Mol Biol 1997; 16:557-567
9. Hoshino M, Takahashi M, Aoike N. Expression of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin immunoreactivity in asthmatic airways and its relationship to angiogenesis. J Allergy Clin Immunol 2001; 107:295-301
10. Asai K, Kanazawa H, Kamoi H, et al. Increased levels of vascular endothelial growth factor in induced sputum in asthmatic patients. Clin Exp Allergy 2003; 33:595-599
11. Dvorak HF, Nagy JA, Feng D, et al. Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis. Curr Top Microbiol Immunol 1999; 237:97-132
12. Peters KG, Kontos CD, Lin PC, et al. Functional significance of Tie 2 signaling in the adult vasculature. Recent Prog Horm Res 2004; 59:51-71
13. Wong AL, Haroon ZA, Werner S, et al. Tie 2 expression and phosphorylation in angiogenic and quiescence adult tissues. Circ Res 1997; 81:567-574
14. Sato TN, Tozawa Y, Deutsch U, et al. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 1995; 376:70-74
15. Thurston G, Suri C, Smith K, et al. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 1999; 286:2511-2514
16. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986. Am Rev Respir Dis 1987; 136:225-244
17. Yoshikawa T, Shoji S, Fujii T, et al. Severity of exercise-induced bronchoconstriction is related to airway eosinophilic inflammation in patients with asthma. Eur Respir J 1998; 12:879-884
18. American Thoracic Society. Recommendation for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children. Am J Respir Crit Care Med 1999; 160:2104-2117
19. Kanazawa H, Hirata K, Yoshikawa J. Role of endogenous nitric oxide in exercise-induced airway narrowing in patients with bronchial asthma. J Allergy Clin Immunol 2000; 106: 1081-1087
20. Kanazawa H, Nomura S, Yoshikawa J. Role of microvascular permeability on physiologic differences in asthma and eosinophilic bronchitis. Am J Respir Crit Care Med 2004; 169: 1125-1130
21. Harfouche R, Hassessian HM, Guo Y, et al. Mechanisms which mediate the antiapoptotic effects of angiopoietin-1 on endothelial cells. Microvasc Res 2002; 64:135-147
22. Hanahan D. Signaling vascular morphogenesis and maintenance. Science 1997; 277:48-50
23. Maisonpierre PC, Suri C, Jones PF, et al. Angiopoietin-2, a natural antagonist for Tie 2 that disrupts in vivo angiogenesis. Science 1997; 277:55-60
24. Zagzag D, Amirnovin R, Greco MA, et al. Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis. Lab Invest 2000; 80:837-849
25. Bhandari V, Choo-Wing R, Lee CG, et al. Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death. Nat Med 2006; 12:1286-1293
26. Daly C, Pasnikowski E, Burova E, et al. Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells. Proc Natl Acad Sci U S A 2006; 17:15491-15496
27. Feltis BN, Wignarajah D, Zheng L, et al. Increased vascular endothelial growth factor and receptors: relationship to angiogenesis in asthma. Am J Respir Crit Care Med 2006; 173:1201-1207
28. Nomura S, Kanazawa H, Hirata K, et al. Relationship between vascular endothelial growth factor and angiopoietin-2 in asthmatics before and after inhaled beclomethasone therapy. J Asthma 2005; 42:141-146
29. Gale NW, Thurston G, Hackett SF. Angiopoietin 2 is required for postnatal angiogenesis and lymphatic patterning, and only the later role is rescued by angiopoietin 1. Dev Cell 2002; 3:411-423
30. Pichiule P, Chavez JC, LaManna JC. Hypoxic regulation of angiopoietin expression in endothelial cells. J Biol Chem 2004; 279:12171-12180
31. McDonald DM. Angiogenesis and remodeling of airway vasculature in chronic inflammation. Am J Respir Crit Care Med 2001; 164:S39-S45
32. Rudolfsson SH, Johansson A, Franck Lissbrant I, et al. Localized expression of angiopoietin 1 and 2 may explain unique characteristics of the rat testicular microvasculature, Biol Reprod 2003; 69:1231-1237
33. Booth H, Richmond I, Ward C, et al. Effects of high-dose inhaled fluticasone propionate on airway inflammation in asthma. Am J Respir Crit Care Med 1995; 152:45-52
34. Chetta A, Zanini A, Forest A, et al. Vascular component of airway remodeling in asthma is reduced by high dose of fluticasone. Am J Respir Crit Care Med 2003; 167:751-757
35. 2-adrenergic receptor agonist formoterol reduces microvascular leakage by inhibiting endothelial gap junction. Am J Physiol 1994; 266:L461-L468
36. Horiuchi T, Weller PF. Expression of vascular endothelial growth factor by human eosinophils: up-regulation by granulocyte macrophage colony-stimulating factor and interleukin-5. Am J Respir Cell Mol Biol 1997; 17:70-77
37. Cristian-Virchow JC, Prasse A, Naya I, et al. Zafirlukast improves asthma control in patients receiving high-dose inhaled corticosteroids. Am J Respir Crit Care Med 2000; 162:578-585
38. O'Sullivan S, Akveld M, Burke CM, et al. Effect of the addition of montelukast to inhaled fluticasone propionate on airway inflammation. Am J Respir Crit Care Med 2003; 167:745-750
39. Kanazawa H, Yoshikawa T, Hirata K, et al. Effects of pranlukast administration on vascular endothelial growth factor levels in asthmatic patients. Chest 2004; 125:1700-1705