Involvement of vascular endothelial growth factor in exercise induced bronchoconstriction in asthmatic patients

Thorax

Volumn 57, Issue 10, 2002, Pages 885-888

  Kanazawa, H ^a   Hirata, K ^a   Yoshikawa, J ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BECLOMETASONE DIPROPIONATE; VASCULOTROPIN;

ADULT; ARTICLE; ASTHMA; BLOOD VESSEL PERMEABILITY; BRONCHOSPASM; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; EXERCISE; EXPIRATORY RESERVE VOLUME; HUMAN; MEDICAL EXAMINATION; PATHOGENESIS; PRIORITY JOURNAL; SPUTUM;

ADMINISTRATION, INHALATION; ADULT; ALBUTEROL; ASTHMA, EXERCISE-INDUCED; BRONCHOCONSTRICTION; BRONCHOCONSTRICTOR AGENTS; BRONCHODILATOR AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL GROWTH FACTORS; EXERCISE; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOKINES; MALE; METHACHOLINE CHLORIDE; SPUTUM; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0036795836     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thorax.57.10.885     Document Type: Article

References (20)

1. McFadden Jr ER, Gilbert A. Exercise-induced asthma. N Eng J Med 1994;330: 1362-7.
2. Barnes PJ, Chung KF, Page CP. Inflammatory mediator and asthma. Phamacol Rev 1988;40:49-84.
3. Neufeld G, Cohen T, Gengrinovitch S, et al. Vascular endothelial growth factor (VEGF) and its receptor. FASEB J 1999;13:9-22.
4. Dvorak HF, Brown LF, Detmar M, et al. Vascular permeability factor/vascular endothelial growth factor, microvoscular hyperpermeability, and angiogenesis. Am J Pathol 1995;146:1029-39.
5. Maniscalco WM, Watkins RH, D'Angio CT, et al. Hyperoxic injury decreases alveolar epithelial cell expression of vascular endothelial growth factor (VEGF) in neonatal rabbit lung. Am J Respir Cell Mol Biol 1997;16:557-67.
6. Hoshino M, Takahashi M, Aoike N. Expression of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin immunoreactivity in asthmatic airways and its relationship to angiogenesis. J Allergy Clin Immunol 2001;107:295-301.
7. American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Dis 1987;136:225-44.
8. Eggleston PA, Guerrant JL. A standard method of evaluating exercise-induced asthma. J Allergy Clin Immunol 1976;58:414-25.
9. Hoshino M, Takahashi M, Takai Y, et al. Inhaled corticosteroids decrease vascularity of the bronchial mucosa in patients with asthma. Clin Exp Allergy 2001;31:722-30.
10. Li X, Wilson JW. Increased vascularity of the bronchial mucosa in mild asthma. Am J Respir Crit Care Med 1997;156:229-33.
11. Esser S, Wolburg K, Wolburg H, et al. Vascular endothelial growth factor induces endothelial fenestrations in vitro. J Cell Biol 1998;140:947-59.
12. Roberts WG, Palade GE. Neovasculature induced by vascular endothelial growth factor is fenestrated. Cancer Res 1997;57:765-72.
13. Nauck M, Roth M, Tamm M, et al. Induction of vascular endothelial growth factor by platelet-activating factor and platelet-derived growth factor is down-regulated by corticosteroids. Am J Respir Cell Mol Biol 1997;16:398-406.
14. McFadden Jr ER. Hypothesis: exercise-induced asthma as a vascular phenomenon. Lancet 1990;335:880-3.
15. Laitinen LA, Laitinen A, Widdicombe J. Effects of inflammatory and other mediators on airway vascular beds. Am Rev Respir Dis 1987;135:567-70.
16. Demoly P, Maly FE, Mautino G, et al. VEGF levels in asthmatic airways do not correlate with plasma extravasation. Clin Exp Allergy 1999;29:1390-4.
17. Yong CL, Hern KL. Vascular endothelial growth factor in patients with acute asthma. J Allergy Clin Immunol 2001;107:1106-7.
18. Barnes PJ. Nitric oxide and airway disease. Ann Med 1995;27:91-7.
19. Scollo M, Zanconato S, Ongaro R, et al. Exhaled nitric oxide and exercise-induced bronchoconstriction in asthmatic children. Am J Respir Crit Care Med 2000;161:1047-50.
20. Kanazawa H, Hirata K, Yoshikawa J. Role of endogenous nitric oxide in exercise-induced airway narrowing in patients with bronchial asthma. J Allergy Clin Immunol 2000;106:1081-7.