MnTMPyP, a metalloporphyrin-based superoxide dismutase/catalase mimetic, protects INS-1 cells and human pancreatic islets from an in vitro oxidative challenge

Diabetes and Metabolism

Volumn 33, Issue 1, 2007, Pages 44-53

  Moriscot, C ^a,b   Candel, S ^a,b   Sauret, V ^b   Kerr Conte, J ^a   Richard, M J ^b   Favrot, M C ^a,b   Benhamou, P Y ^a,b  

^a INSERM   (France)

^b GRENOBLE UNIVERSITY HOSPITAL   (France)

Author keywords

Cytoprotection; INS 1 cells; Islet of Langerhans; Oxidative stress; SOD mimics

Indexed keywords

HYPOXANTHINE; MANGANESE TETRAKIS (1 METHYL 4 PYRIDYL) PORPHYRIN; MENADIONE; METALLOPORPHYRIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; XANTHINE OXIDASE; MANGANESE; MN(III) 5,10,15,20 TETRAKIS(N METHYLPYRIDINIUM 2 YL)PORPHYRIN; MN(III) 5,10,15,20-TETRAKIS(N-METHYLPYRIDINIUM-2-YL)PORPHYRIN; REACTIVE OXYGEN METABOLITE; VASODILATOR AGENT;

ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HUMAN; HUMAN CELL; IN VITRO STUDY; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; ANIMAL; CELL LINE; CELL SURVIVAL; CYTOLOGY; METABOLISM; OXIDATIVE STRESS; PANCREAS ISLET; PHYSIOLOGY; RAT;

ANIMALS; CELL LINE; CELL SURVIVAL; HUMANS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MANGANESE; METALLOPORPHYRINS; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; VASODILATOR AGENTS;

EID: 34247213906     PISSN: 12623636     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabet.2006.09.004     Document Type: Article

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