Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and Gαi activation

Journal of Biological Chemistry

Volumn 282, Issue 8, 2007, Pages 5111-5115

  Berchiche, Yamina A ^a,b   Chow, Ken Y ^c   Lagane, Bernard ^c   Leduc, Martin ^a,b   Percherancier, Yann ^a   Fujii, Nobutaka ^d   Tamamura, Hirokazu ^e   Bachelerie, Françoise ^c   Heveker, Nikolaus ^a,b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

^c INSTITUT PASTEUR   (France)

^d KYOTO UNIVERSITY   (Japan)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CHEMOKINE RECEPTORS; G PROTEIN COUPLED RECEPTORS (GPCR);

AMINO ACIDS; BIOLUMINESCENCE; COMPLEXATION; CONFORMATIONS; MOLECULAR STRUCTURE; MUTAGENESIS;

PROTEINS;

ARGININE; ASPARAGINE; CHEMOKINE RECEPTOR CXCR4; G PROTEIN COUPLED RECEPTOR; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MUTANT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT;

ARTICLE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CONFORMATIONAL TRANSITION; CORRELATION ANALYSIS; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; AMINO ACID SUBSTITUTION; ANIMAL; BIOLOGICAL MODEL; CELL LINE; GENETICS; METABOLISM; SIGNAL TRANSDUCTION;

AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; GTP-BINDING PROTEIN ALPHA SUBUNITS; HUMANS; MODELS, BIOLOGICAL; PROTEIN CONFORMATION; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION;

EID: 34247158219     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C600270200     Document Type: Article

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