Early responses associated with chronic pathology in murine schistosomiasis

Parasite Immunology

Volumn 29, Issue 5, 2007, Pages 241-249

  Cetre Sossah C B ^a,b   Montesano, M A ^a,c   Freeman Jr , G L ^a   Willard, M T ^a,d   Colley, D G ^a,e   Secor, W E ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b CIRAD   (France)

^c NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF GEORGIA   (United States)

Author keywords

Cytokines; Idiotypes; Mice; Schistosomiasis; Splenomegaly

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYDROXYPROLINE; IMMUNOGLOBULIN IDIOTYPE; INTERLEUKIN 4; INTERLEUKIN 5; IONOMYCIN; NITRIC OXIDE; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS REACTION; CYTOKINE PRODUCTION; DISEASE SEVERITY; HYPERSPLENISM; IMMUNOGLOBULIN BLOOD LEVEL; MALE; MORBIDITY; MOUSE; NONHUMAN; PARASITE IDENTIFICATION; PERITONEUM CELL; PRIORITY JOURNAL; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; SPLEEN CELL; SPLEEN SIZE; SPLENOMEGALY; T LYMPHOCYTE ACTIVATION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; CROSS REACTIONS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HYDROXYPROLINE; IMMUNOGLOBULIN IDIOTYPES; MALE; MICE; MICE, INBRED CBA; NITRIC OXIDE; PARASITE EGG COUNT; SCHISTOSOMIASIS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; MURINAE; MUS; SCHISTOSOMA MANSONI;

EID: 34247154422     PISSN: 01419838     EISSN: 13653024     Source Type: Journal    
DOI: 10.1111/j.1365-3024.2007.00939.x     Document Type: Article

References (40)

1. King CL, Dickman K & Tisch DJ. Reassessment of the cost of chronic helminthic infection: a meta-analysis of disability-related outcomes in endemic schistosomiasis. Lancet 2005; 365: 1561-1569.
2. van der Werf MJ, de Vlas SJ, Brooker S et al. Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa. Acta Tropica 2003; 86: 125-139.
3. Colley DG, Garcia AA, Lambertucci JR et al. Immune responses during human schistosomiasis. XII. Differential responsiveness in patients with hepatosplenic disease. Am J Trop Med Hyg 1986; 35: 793-802.
4. Pearce EJ & MacDonald AS. The immunobiology of schistosomiasis. Nat Rev Immunol 2002; 2: 499-511.
5. Vennervald BJ & Dunne DW. Morbidity in schistosomiasis: an update. Curr Opin Infect Dis 2004; 17: 439-447.
6. Abath FGC, Morais CNL, Montenegro CEL, Wynn TA & Montenegro SML. Immunopathogenic mechanisms in schistosomiasis: what can be learnt from human studies? Trends Parasitol 2006; 22: 85-91.
7. Henderson GS, Nix NA, Montesano MA et al. Two distinct pathological syndromes in male CBA/J inbred mice with chronic S. mansoni infection. Am J Pathol 1993; 142: 703-714.
8. Freeman GL Jr, Montesano MA, Secor WE, Colley DG, Howard MJ & Bosshardt SC. Immunopathogenesis and immunoregulation in schistosomiasis. Distinct chronic pathologic syndromes in CBA/J mice. Ann N Y Acad Sci 1996; 797: 151-165.
9. Montesano MA, Colley DG, Willard MT, Freeman GL Jr & Secor WE. Idiotypes expressed early in experimental Schistosoma mansoni infections predict clinical outcomes of chronic disease. J Exp Med 2002; 195: 1223-1228.
10. Montesano MA, Freeman GL Jr, Gazzinelli G & Colley DG. Expression of cross-reactive, shared idiotypes on anti-SEA antibodies from humans and mice with schistosomiasis. J Immunol 1990; 145: 1002-1008.
11. Montesano MA, Lima MS, Correa-Oliveira R, Gazzinelli G & Colley DG. Immune response during human schistosomiasis mansoni. XVI. Idiotypic differences in antibody preparations from patients with different clinical forms of infection. J Immunol 1989; 142: 2501-2506.
12. Montesano MA, Colley DG, Eloi-Santos S, Freeman GL Jr & Secor WE. Neonatal idiotypic exposure alters subsequent cytokine, pathology and survival patterns in experimental Schistosoma mansoni infections. J Exp Med 1999; 189: 637-645.
13. Colley DG, Montesano MA, Freeman GL Jr & Secor WE. Infection-stimulated or perinatal-initiated idiotypic interactions can direct differential morbidity and mortality in schistosomiasis. Microbes Infect 1999; 1: 517-524.
14. Montesano MA, Colley DG, Freeman GL Jr & Secor WE. Neonatal exposure to idiotype induces Schistosoma mansoni egg antigen-specific cellular and humoral immune responses. J Immunol 1999; 163: 898-905.
15. Cheever AW & Warren KS. Hepatic blood flow in mice with acute hepato-splenic schistosomiasis mansoni. Trans R Soc Trop Med Hyg 1964; 5: 406-412.
16. Bergman I & Loxley R. Two improved and simplified methods for the spectrophotometric determination of hydroxyproline. Anal Chem 1963; 35: 1-5.
17. Cheever AW, Finkelman FD, Caspar P, Heiny S, Macedonia JG & Sher A. Treatment with anti-IL-2 antibodies reduces hepatic pathology and eosinophilia in Schistosoma mansoni-infected mice while selectively inhibiting T cell IL-5 production. J Immunol 1992; 148: 3244-3248.
18. Colley DG, Cook JA, Freeman GL Jr, Bartholomew RK & Jordon P. Immune responses during human schistosomiasis mansoni. I. In vitro lymphocyte blastogenic responses to heterologous antigenic preparations from schistosome eggs, worms, and cercariae. Int Arch Allergy Appl Immunol 1977; 53: 420-433.
19. Carter CE & Colley DG. An electrophoretic analysis of Schistosoma mansoni soluble egg antigenic preparation. J Parasitol 1978; 64: 285-290.
20. Hesse M, Modolell M, La Flamme AC et al. Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of 1-arginine metabolism. J Immunol 2001; 167: 6533-6544.
21. Pearce EJ, Caspar EJ, Grzych JM, Lewis FA & Sher A. Down-regulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J Exp Med 1991; 173: 159-166.
22. Grzych JM, Pearce E, Cheever A et al. Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni. J Immunol 1991; 146: 1322-1327.
23. Kaplan MH, Whitfield JR, Boros DL & Grusby MJ. Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response. J Immunol 1998; 160: 1850-1856.
24. Jankovic D, Kullberg MC, Noben-Trauth N et al. Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile. J Immunol 1999; 163: 337-342.
25. + T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection. J Immunol 1991; 147: 2713-2716.
26. Lukacs NW & Boros DL. Lymphokine regulation of granuloma formation in murine schistosomiasis mansoni. Clin Immunol Immunopathol 1993; 68: 57-63.
27. Wynn TA, Jankovic D, Hieny S et al. IL-12 exacerbates rather than suppresses T helper 2-dependent pathology in the absences of exogenous IFN-γ. J Immunol 1995; 154: 3999-4009.
28. Falcao PL, Malaquias LC, Martins-Filho OA et al. Human schistosomiasis mansoni: IL-10 modulates the in vitro granuloma formation. Parasite Immunol 1998; 20: 447-454.
29. Hoffman KF, Caspar P, Cheever AW & Wynn TA. IFN-γ, IL-12, and TNF-α are required to maintain reduced liver pathology in mice vaccinated with Schistosoma mansoni eggs and IL-12. J Immunol 1998; 161: 4201-4210.
30. Mountford AP, Coulson PS, Cheever AW, Sher A, Wilson RA & Wynn TA. Interleukin-12 can directly induce T-helper 1 responses in interferon-γ (IFN-γ) receptor-deficient mice, but requires IFN-γ signaling to downregulate T-helper 2 responses. Immunology 1999; 97: 588-594.
31. Henri S, Chevillard C, Mergani A et al. Cytokine regulation of periportal fibrosis in humans infected with Schistosoma mansoni: IFN-γ is associated with protection against fibrosis and TNF-α with aggravation of disease. J Immunol 2002; 169: 929-936.
32. Hesse M, Piccirillo CA, Belkaid Y et al. The pathogenesis of schistosomiasis is controlled by cooperation IL-10-producing innate effector and regulatory T cells. J Immunol 2004; 172: 3157-3166.
33. Bosshardt SC, Freeman GL Jr, Secor WE & Colley DG. IL-10 deficit correlates with chronic, hypersplenomegaly syndrome in male CBA/J mice infected with Schistosoma mansoni. Parasite Immunol 1997; 19: 347-353.
34. +) outgrowth in murine schistosomiasis is genetically restricted and largely due to activation by polylactosamine sugars. J Immunol 1997; 158: 338-344.
35. Adewusi OI, Nix NA, Lu X, Colley DG & Secor WE. Schistosoma mansoni: relationship of tumor necrosis factor-alpha to morbidity and collagen deposition in chronic experimental infection. Exp Parasitol 1996; 84: 115-123.
36. Joseph AL & Boros DL. Tumor necrosis factor plays a role in Schistosoma mansoni egg-induced granulomatous inflammation. J Immunol 1993; 151: 5461-5471.
37. Oliveira DM, Silva-Teixeira DN & Goes AM. Evidence for nitric oxide action on in vitro granuloma formation through pivotal changes in MIP-1α and IL-10 release in human schistosomiasis. Nitric Oxide 1999; 3: 162-171.
38. Modolell M, Corraliza I, Link F, Soler G & Eichmann K. Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow-derived macrophages by TH1 and TH2 cytokines. Eur J Immunol 1995; 25: 1101-1104.
39. Ferru I, Roye O, Delacre M, Auriault C & Wolwczuk I. Infection of B-cell-deficient mice by the parasite Schistosoma mansoni: demonstration of the participation of B cell in granuloma modulation. Scand J Immunol 1998; 48: 233-240.
40. + T cell-mediated granulomatous pathology in schistosomiasis is downregulated by a B cell-dependent mechanism requiring Fc receptor signaling. J Exp Med 1998; 187: 619-629.