Interleukin-12 can directly induce T-helper 1 responses in interferon- γ (IFN-γ) receptor-deficient mice, but requires IFN-γ signalling to downregulate T-helper 2 responses

Immunology

Volumn 97, Issue 4, 1999, Pages 588-594

  Mountford, A P ^a   Coulson, P S ^a   Cheever, A W ^b   Sher, A ^b   Wilson, R A ^a   Wynn, T A ^b  

^a UNIVERSITY OF YORK   (United Kingdom)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INTERLEUKIN 12;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HELPER CELL; IMMUNOREGULATION; LUNG GRANULOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; T LYMPHOCYTE ACTIVATION;

ANIMALS; CELL CULTURE TECHNIQUES; DOWN-REGULATION; GRANULOMA; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-4; INTERLEUKIN-5; MICE; MICE, INBRED STRAINS; RECEPTORS, INTERFERON; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SCHISTOSOMIASIS MANSONI; TH1 CELLS; TH2 CELLS;

EID: 0032782399     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1999.00832.x     Document Type: Article

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