-
1
-
-
0035829827
-
Decoupling cell growth and product formation in Chinese hamster ovary cells through metabolic control
-
Altamirano C., Cairo J.J., and Godia F. Decoupling cell growth and product formation in Chinese hamster ovary cells through metabolic control. Biotechnol. Bioeng. 76 4 (2001) 351-360
-
(2001)
Biotechnol. Bioeng.
, vol.76
, Issue.4
, pp. 351-360
-
-
Altamirano, C.1
Cairo, J.J.2
Godia, F.3
-
2
-
-
0033952514
-
Improvement of CHO cell culture medium formulation: simultaneous substitution of glucose and glutamine
-
Altamirano C., Paredes C., Cairo J.J., and Godia F. Improvement of CHO cell culture medium formulation: simultaneous substitution of glucose and glutamine. Biotechnol. Prog. 16 1 (2000) 69-75
-
(2000)
Biotechnol. Prog.
, vol.16
, Issue.1
, pp. 69-75
-
-
Altamirano, C.1
Paredes, C.2
Cairo, J.J.3
Godia, F.4
-
3
-
-
14744283551
-
High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker
-
Bebbington C.R., Renner G., Thomson S., King D., Abrams D., and Yarranton G.T. High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker. Biotechnology (NY) 10 2 (1992) 169-175
-
(1992)
Biotechnology (NY)
, vol.10
, Issue.2
, pp. 169-175
-
-
Bebbington, C.R.1
Renner, G.2
Thomson, S.3
King, D.4
Abrams, D.5
Yarranton, G.T.6
-
4
-
-
0029104088
-
In pursuit of the optimal fed-batch process for monoclonal antibody production
-
Bibila T.A., and Robinson D.K. In pursuit of the optimal fed-batch process for monoclonal antibody production. Biotechnol. Prog. 11 1 (1995) 1-13
-
(1995)
Biotechnol. Prog.
, vol.11
, Issue.1
, pp. 1-13
-
-
Bibila, T.A.1
Robinson, D.K.2
-
5
-
-
33845616177
-
Phenotypic consequences of promoter-mediated transcriptional noise
-
Blake W.J., Balázsi G., Kohanski M.A., Isaacs F.J., Murphy K.F., Kuang Y., Cantor C.R., Walt D., and Collins J.J. Phenotypic consequences of promoter-mediated transcriptional noise. Mol. Cell 24 6 (2006) 853-865
-
(2006)
Mol. Cell
, vol.24
, Issue.6
, pp. 853-865
-
-
Blake, W.J.1
Balázsi, G.2
Kohanski, M.A.3
Isaacs, F.J.4
Murphy, K.F.5
Kuang, Y.6
Cantor, C.R.7
Walt, D.8
Collins, J.J.9
-
6
-
-
0027439605
-
Rhodamine 123 fluorescence of immortal hybridoma cell lines as a function of glucose concentration
-
Borth N., Kral G., and Katinger H. Rhodamine 123 fluorescence of immortal hybridoma cell lines as a function of glucose concentration. Cytometry 14 1 (1993) 70-73
-
(1993)
Cytometry
, vol.14
, Issue.1
, pp. 70-73
-
-
Borth, N.1
Kral, G.2
Katinger, H.3
-
7
-
-
23844433927
-
Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals
-
Butler M. Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals. Appl. Microbiol. Biotechnol. 68 3 (2005) 283-291
-
(2005)
Appl. Microbiol. Biotechnol.
, vol.68
, Issue.3
, pp. 283-291
-
-
Butler, M.1
-
8
-
-
8744248873
-
The selection of high producing cell lines using flow cytometry and cell sorting
-
Carroll S., and Al-Rubeai M. The selection of high producing cell lines using flow cytometry and cell sorting. Exp. Op. Biolog. Ther. 4 11 (2004) 1821-1829
-
(2004)
Exp. Op. Biolog. Ther.
, vol.4
, Issue.11
, pp. 1821-1829
-
-
Carroll, S.1
Al-Rubeai, M.2
-
9
-
-
0024148694
-
Mitochondrial membrane potential in living cells
-
Chen L.B. Mitochondrial membrane potential in living cells. Ann. Rev. Cell Biol. 4 (1988) 155-181
-
(1988)
Ann. Rev. Cell Biol.
, vol.4
, pp. 155-181
-
-
Chen, L.B.1
-
10
-
-
0031576736
-
Physiology of cultured animal cells
-
Doverskog M., Ljunggren J., Ohman L., and Haggstrom L. Physiology of cultured animal cells. J. Biotechnol. 59 1/2 (1997) 103-115
-
(1997)
J. Biotechnol.
, vol.59
, Issue.1-2
, pp. 103-115
-
-
Doverskog, M.1
Ljunggren, J.2
Ohman, L.3
Haggstrom, L.4
-
11
-
-
0031911389
-
Descriptive parameter evaluation in mammalian cell culture
-
Dutton R., Scharer J., and Moo-Young M. Descriptive parameter evaluation in mammalian cell culture. Cytotechnology 26 2 (1998) 139-152
-
(1998)
Cytotechnology
, vol.26
, Issue.2
, pp. 139-152
-
-
Dutton, R.1
Scharer, J.2
Moo-Young, M.3
-
12
-
-
0034606665
-
Multiple steady states with distinct cellular metabolism in continuous culture of mammalian cells
-
Europa A.F., Gambhir A., Fu P.C., and Hu W.S. Multiple steady states with distinct cellular metabolism in continuous culture of mammalian cells. Biotechnol. Bioeng. 67 1 (2000) 25-34
-
(2000)
Biotechnol. Bioeng.
, vol.67
, Issue.1
, pp. 25-34
-
-
Europa, A.F.1
Gambhir, A.2
Fu, P.C.3
Hu, W.S.4
-
13
-
-
1842425836
-
Impact of temperature reduction and expression of yeast pyruvate carboxylase on hGM-CSF-producing CHO cells
-
Fogolin M.B., Wagner R., Etcheverrigaray M., and Kratje R. Impact of temperature reduction and expression of yeast pyruvate carboxylase on hGM-CSF-producing CHO cells. J. Biotechnol. 109 1/2 (2004) 179-191
-
(2004)
J. Biotechnol.
, vol.109
, Issue.1-2
, pp. 179-191
-
-
Fogolin, M.B.1
Wagner, R.2
Etcheverrigaray, M.3
Kratje, R.4
-
14
-
-
0942265268
-
Maximizing interferon-gamma production by Chinese hamster ovary cells through temperature shift optimization: experimental and modeling
-
Fox S.R., Patel U.A., Yap M.G., and Wang D.I. Maximizing interferon-gamma production by Chinese hamster ovary cells through temperature shift optimization: experimental and modeling. Biotechnol. Bioeng. 85 2 (2004) 177-184
-
(2004)
Biotechnol. Bioeng.
, vol.85
, Issue.2
, pp. 177-184
-
-
Fox, S.R.1
Patel, U.A.2
Yap, M.G.3
Wang, D.I.4
-
15
-
-
0032808184
-
Alteration of cellular metabolism by consecutive fed-batch cultures of mammalian cells
-
Gambhir A., Europa A.F., and Hu W.S. Alteration of cellular metabolism by consecutive fed-batch cultures of mammalian cells. J. Biosci. Bioeng. 87 6 (1999) 805-810
-
(1999)
J. Biosci. Bioeng.
, vol.87
, Issue.6
, pp. 805-810
-
-
Gambhir, A.1
Europa, A.F.2
Hu, W.S.3
-
16
-
-
0038367650
-
Analysis of cellular metabolism of hybridoma cells at distinct physiological states
-
Gambhir A., Korke R., Lee J., Fu P.C., Europa A., and Hu W.S. Analysis of cellular metabolism of hybridoma cells at distinct physiological states. J. Biosci. Bioeng. 95 4 (2003) 317-327
-
(2003)
J. Biosci. Bioeng.
, vol.95
, Issue.4
, pp. 317-327
-
-
Gambhir, A.1
Korke, R.2
Lee, J.3
Fu, P.C.4
Europa, A.5
Hu, W.S.6
-
17
-
-
0032078486
-
Intracellular UDP-N-acetylhexosamine pool affects N-Glycan complexity: A mechanism of ammonium action on protein glycosylation
-
Grammatikos S.I., Valley U., Numtz M., Conradr H.S., and Wagner R. Intracellular UDP-N-acetylhexosamine pool affects N-Glycan complexity: A mechanism of ammonium action on protein glycosylation. Biotechn. Progr. 14 3 (1998) 410-419
-
(1998)
Biotechn. Progr.
, vol.14
, Issue.3
, pp. 410-419
-
-
Grammatikos, S.I.1
Valley, U.2
Numtz, M.3
Conradr, H.S.4
Wagner, R.5
-
18
-
-
0037186256
-
Expression of recombinant cytoplasmic yeast pyruvate carboxylase for the improvement of the production of human erythropoietin by recombinant BHK-21 cells
-
Irani N., Beccaria A.J., and Wagner R. Expression of recombinant cytoplasmic yeast pyruvate carboxylase for the improvement of the production of human erythropoietin by recombinant BHK-21 cells. J. Biotechnol. 93 3 (2002) 269-282
-
(2002)
J. Biotechnol.
, vol.93
, Issue.3
, pp. 269-282
-
-
Irani, N.1
Beccaria, A.J.2
Wagner, R.3
-
19
-
-
0033385223
-
Improvement of the primary metabolism of cell cultures by introducing a new cytoplasmic pyruvate carboxylase reaction
-
Irani N., Wirth M., van Den Heuvel J., and Wagner R. Improvement of the primary metabolism of cell cultures by introducing a new cytoplasmic pyruvate carboxylase reaction. Biotechnol. Bioeng. 66 4 (1999) 238-246
-
(1999)
Biotechnol. Bioeng.
, vol.66
, Issue.4
, pp. 238-246
-
-
Irani, N.1
Wirth, M.2
van Den Heuvel, J.3
Wagner, R.4
-
20
-
-
0346363685
-
Large scale gene expression profiling of metabolic shift of mammalian cells in culture
-
Korke R., Gatti Mde L., Lau A.L., Lim J.W., Seow T.K., Chung M.C., and Hu W.S. Large scale gene expression profiling of metabolic shift of mammalian cells in culture. J. Biotechnol. 107 1 (2004) 1-17
-
(2004)
J. Biotechnol.
, vol.107
, Issue.1
, pp. 1-17
-
-
Korke, R.1
Gatti Mde, L.2
Lau, A.L.3
Lim, J.W.4
Seow, T.K.5
Chung, M.C.6
Hu, W.S.7
-
21
-
-
0034606680
-
Stable recombinant expression of the anti HIV-1 monoclonal antibody 2F5 after IgG3/IgG1 subclass switch in CHO cells
-
Kunert R., Steinfellner W., Purtscher M., Assadian A., and Katinger H. Stable recombinant expression of the anti HIV-1 monoclonal antibody 2F5 after IgG3/IgG1 subclass switch in CHO cells. Biotechnol. Bioeng. 67 1 (2000) 97-103
-
(2000)
Biotechnol. Bioeng.
, vol.67
, Issue.1
, pp. 97-103
-
-
Kunert, R.1
Steinfellner, W.2
Purtscher, M.3
Assadian, A.4
Katinger, H.5
-
22
-
-
33645774926
-
Applications of cell sorting in biotechnology
-
Mattanovich D., and Borth N. Applications of cell sorting in biotechnology. Microb. Cell Fact. 5 (2006) 12
-
(2006)
Microb. Cell Fact.
, vol.5
, pp. 12
-
-
Mattanovich, D.1
Borth, N.2
-
23
-
-
0030049769
-
Comparative analysis of glucose and glutamine metabolism in transformed mammalian cell lines, insect and primary liver cells
-
Neermann J., and Wagner R. Comparative analysis of glucose and glutamine metabolism in transformed mammalian cell lines, insect and primary liver cells. J. Cell Physiol. 166 1 (1996) 152-169
-
(1996)
J. Cell Physiol.
, vol.166
, Issue.1
, pp. 152-169
-
-
Neermann, J.1
Wagner, R.2
-
24
-
-
0030088497
-
Analysis of nutritional factors and physical conditions affecting growth and monoclonal antibody production of the hybridoma KB-26.5 cell line
-
Sanfeliu A., Cairo J.J., Casas C., Sola C., and Godia F. Analysis of nutritional factors and physical conditions affecting growth and monoclonal antibody production of the hybridoma KB-26.5 cell line. Biotechnol. Prog. 12 2 (1996) 209-216
-
(1996)
Biotechnol. Prog.
, vol.12
, Issue.2
, pp. 209-216
-
-
Sanfeliu, A.1
Cairo, J.J.2
Casas, C.3
Sola, C.4
Godia, F.5
-
25
-
-
0035515020
-
Proteomic investigation of metabolic shift in mammalian cell culture
-
Seow T.K., Korke R., Liang R.C., Ong S.E., Ou K., Wong K., Hu W.S., and Chung M.C. Proteomic investigation of metabolic shift in mammalian cell culture. Biotechnol. Prog. 17 6 (2001) 1137-1144
-
(2001)
Biotechnol. Prog.
, vol.17
, Issue.6
, pp. 1137-1144
-
-
Seow, T.K.1
Korke, R.2
Liang, R.C.3
Ong, S.E.4
Ou, K.5
Wong, K.6
Hu, W.S.7
Chung, M.C.8
-
26
-
-
0344563583
-
Adaptive control at low glucose concentration of HEK-293 cell serum-free cultures
-
Siegwart P., Cote J., Male K., Luong J.H., Perrier M., and Kamen A. Adaptive control at low glucose concentration of HEK-293 cell serum-free cultures. Biotechnol. Prog. 15 4 (1999) 608-616
-
(1999)
Biotechnol. Prog.
, vol.15
, Issue.4
, pp. 608-616
-
-
Siegwart, P.1
Cote, J.2
Male, K.3
Luong, J.H.4
Perrier, M.5
Kamen, A.6
-
27
-
-
33747126481
-
Process parameter shifting. Part I. Effect of DOT, pH and temperature on the performance of Epo-Fc expressing CHO cells cultivated in controlled bioreactors
-
Trummer E., Fauland K., Seidinger S., Schreibl K., Lattenmayer C., Kunert R., Vorauer-Uhl K., Weik R., Borth N., Katinger K., and Müller D. Process parameter shifting. Part I. Effect of DOT, pH and temperature on the performance of Epo-Fc expressing CHO cells cultivated in controlled bioreactors. Biotechnol. Bioeng. 94 6 (2006) 1033-1044
-
(2006)
Biotechnol. Bioeng.
, vol.94
, Issue.6
, pp. 1033-1044
-
-
Trummer, E.1
Fauland, K.2
Seidinger, S.3
Schreibl, K.4
Lattenmayer, C.5
Kunert, R.6
Vorauer-Uhl, K.7
Weik, R.8
Borth, N.9
Katinger, K.10
Müller, D.11
-
28
-
-
0033588177
-
Incorporation of ammonium into intracellular UDP-activated N-acetylhexosamines and into carbohydrate structures in glycoproteins
-
Valley U., Nimtz M., Conradt H.S., and Wagner R. Incorporation of ammonium into intracellular UDP-activated N-acetylhexosamines and into carbohydrate structures in glycoproteins. Biotechnol. Bioeng. 64 4 (1999) 401-417
-
(1999)
Biotechnol. Bioeng.
, vol.64
, Issue.4
, pp. 401-417
-
-
Valley, U.1
Nimtz, M.2
Conradt, H.S.3
Wagner, R.4
-
29
-
-
0037379220
-
Characterization of human class-switched polymeric (immunoglobulin M [IgM] and IgA) anti-human immunodeficiency virus type 1 antibodies 2F5 and 2G12
-
Wolbank S., Kunert R., Stiegler G., and Katinger H. Characterization of human class-switched polymeric (immunoglobulin M [IgM] and IgA) anti-human immunodeficiency virus type 1 antibodies 2F5 and 2G12. J. Virol. 77 7 (2003) 4095-4103
-
(2003)
J. Virol.
, vol.77
, Issue.7
, pp. 4095-4103
-
-
Wolbank, S.1
Kunert, R.2
Stiegler, G.3
Katinger, H.4
-
30
-
-
0032549607
-
Determinants and rate laws of growth and death of hybridoma cells in continuous culture
-
Zeng A.P., Deckwer W.D., and Hu W.S. Determinants and rate laws of growth and death of hybridoma cells in continuous culture. Biotechnol. Bioeng. 57 6 (1998) 642-654
-
(1998)
Biotechnol. Bioeng.
, vol.57
, Issue.6
, pp. 642-654
-
-
Zeng, A.P.1
Deckwer, W.D.2
Hu, W.S.3
-
31
-
-
0032077416
-
Variation of stoichiometric ratios and their correlation for monitoring and control of animal cell cultures
-
Zeng A.P., Hu W.S., and Deckwer W.D. Variation of stoichiometric ratios and their correlation for monitoring and control of animal cell cultures. Biotechnol. Prog. 14 3 (1998) 434-441
-
(1998)
Biotechnol. Prog.
, vol.14
, Issue.3
, pp. 434-441
-
-
Zeng, A.P.1
Hu, W.S.2
Deckwer, W.D.3
-
32
-
-
0030916886
-
Alteration of mammalian cell metabolism by dynamic nutrient feeding
-
Zhou W.R.J., Europa A., and Hu W.-S. Alteration of mammalian cell metabolism by dynamic nutrient feeding. Cytotechnology 24 (1997) 99-108
-
(1997)
Cytotechnology
, vol.24
, pp. 99-108
-
-
Zhou, W.R.J.1
Europa, A.2
Hu, W.-S.3
|