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Volumn 178, Issue 8, 2007, Pages 5048-5057

A critical role for p53 in the control of NF-κB-dependent gene expression in TLR4-stimulated dendritic cells exposed to genistein

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GENISTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; ISOFLAVONE DERIVATIVE; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE 1; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

EID: 34247137556     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.8.5048     Document Type: Article
Times cited : (79)

References (68)
  • 1
    • 0032984234 scopus 로고    scopus 로고
    • Characteristics and occurrence of phenolic phytochemicals
    • King, A., and G. Young. 1999. Characteristics and occurrence of phenolic phytochemicals. J. Am. Diet. Assoc. 99: 213-218.
    • (1999) J. Am. Diet. Assoc , vol.99 , pp. 213-218
    • King, A.1    Young, G.2
  • 3
    • 4143148752 scopus 로고    scopus 로고
    • Soy isoflavone phyto-pharmaceuticals in interleukin-6 affections: Multi-purpose nutraceuticals at the crossroad of hormone replacement, anti-cancer and antiinflammatory therapy
    • Dijsselbloem, N., W. Vanden Beighe, A. De Naeyer, and G. Haegeman. 2004. Soy isoflavone phyto-pharmaceuticals in interleukin-6 affections: multi-purpose nutraceuticals at the crossroad of hormone replacement, anti-cancer and antiinflammatory therapy. Biochem. Pharmacol. 68: 1171-1185.
    • (2004) Biochem. Pharmacol , vol.68 , pp. 1171-1185
    • Dijsselbloem, N.1    Vanden Beighe, W.2    De Naeyer, A.3    Haegeman, G.4
  • 4
    • 33646424342 scopus 로고    scopus 로고
    • Attenuation of mitogen- and stress-activated protein kinase-1-driven nuclear factor-κB gene expression by soy isoflavones does not require estrogenic activity
    • Vanden Berghe, W., N. Dijsselbloem, L. Vermeulen, N. Ndlovu, E. Boone, and G. Haegeman. 2006. Attenuation of mitogen- and stress-activated protein kinase-1-driven nuclear factor-κB gene expression by soy isoflavones does not require estrogenic activity. Cancer Res. 66: 4852-4862.
    • (2006) Cancer Res , vol.66 , pp. 4852-4862
    • Vanden Berghe, W.1    Dijsselbloem, N.2    Vermeulen, L.3    Ndlovu, N.4    Boone, E.5    Haegeman, G.6
  • 5
    • 28244468088 scopus 로고    scopus 로고
    • Estrogen receptor-independent inhibition of tumor necrosis factor-α gene expression by phytoestrogen equol is mediated by blocking nuclear factor-κB activation in mouse macrophages
    • Kang, J. S., Y. D. Yoon, M. H. Han, S. B. Han, K. Lee, M. R. Kang, E. Y. Moon, Y. J. Jeon, S. K. Park, and H. M. Kim. 2005. Estrogen receptor-independent inhibition of tumor necrosis factor-α gene expression by phytoestrogen equol is mediated by blocking nuclear factor-κB activation in mouse macrophages. Biochem. Pharmacol. 71: 136-143.
    • (2005) Biochem. Pharmacol , vol.71 , pp. 136-143
    • Kang, J.S.1    Yoon, Y.D.2    Han, M.H.3    Han, S.B.4    Lee, K.5    Kang, M.R.6    Moon, E.Y.7    Jeon, Y.J.8    Park, S.K.9    Kim, H.M.10
  • 6
    • 0041589149 scopus 로고    scopus 로고
    • Inactivation of NF-κB by genistein is mediated via Akt signaling pathway in breast cancer cells
    • Gong, L., Y. Li, A. Nedeljkovic-Kurepa, and F. H. Sarkar. 2003. Inactivation of NF-κB by genistein is mediated via Akt signaling pathway in breast cancer cells. Oncogene 22: 4702-4709.
    • (2003) Oncogene , vol.22 , pp. 4702-4709
    • Gong, L.1    Li, Y.2    Nedeljkovic-Kurepa, A.3    Sarkar, F.H.4
  • 7
    • 33644833880 scopus 로고    scopus 로고
    • Genistein, estrogen receptors, and the acquired immune response
    • Cooke, P. S., V. Selvaraj, and S. Yellayi. 2006. Genistein, estrogen receptors, and the acquired immune response. J. Nutr. 136: 704-708.
    • (2006) J. Nutr , vol.136 , pp. 704-708
    • Cooke, P.S.1    Selvaraj, V.2    Yellayi, S.3
  • 8
    • 2342561171 scopus 로고    scopus 로고
    • Controlling the Toll road to dendritic cell polarization
    • Mazzoni, A., and D. M. Segal. 2004. Controlling the Toll road to dendritic cell polarization. J. Leukocyte Biol. 75: 721-730.
    • (2004) J. Leukocyte Biol , vol.75 , pp. 721-730
    • Mazzoni, A.1    Segal, D.M.2
  • 9
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13: 251-276.
    • (1995) Annu. Rev. Immunol , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 10
    • 0025222698 scopus 로고
    • IL-4 directs the development of Th2-like helper effectors
    • Swain, S. L., A. D. Weinberg, M. English, and G. Huston. 1990. IL-4 directs the development of Th2-like helper effectors. J. Immunol. 145: 3796-3806.
    • (1990) J. Immunol , vol.145 , pp. 3796-3806
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3    Huston, G.4
  • 11
    • 0036889996 scopus 로고    scopus 로고
    • The two faces of IL-6 on Th1/Th2 differentiation
    • Diehl, S., and M. Rincon. 2002. The two faces of IL-6 on Th1/Th2 differentiation. MoI. Immunol. 39: 531-536.
    • (2002) MoI. Immunol , vol.39 , pp. 531-536
    • Diehl, S.1    Rincon, M.2
  • 13
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E., Y. Carrier, W. Gao, T. Korn, T. B. Strom, M. Oukka, H. L. Weiner, and V. K. Kuchroo. 2006. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441: 235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 14
    • 0031913593 scopus 로고    scopus 로고
    • Interleukin 6 and its receptor: Ten years later
    • Hirano, T. 1998. Interleukin 6 and its receptor: ten years later. Int. Rev. Immunol. 16: 249-284.
    • (1998) Int. Rev. Immunol , vol.16 , pp. 249-284
    • Hirano, T.1
  • 15
    • 24744435772 scopus 로고    scopus 로고
    • Directing transition from innate to acquired immunity: Defining a role for IL-6
    • Jones, S. A. 2005. Directing transition from innate to acquired immunity: defining a role for IL-6. J. Immunol. 175: 3463-3468.
    • (2005) J. Immunol , vol.175 , pp. 3463-3468
    • Jones, S.A.1
  • 16
    • 25444466478 scopus 로고    scopus 로고
    • Cytokine signal regulation and autoimmune disorders
    • Nishimoto, N. 2005. Cytokine signal regulation and autoimmune disorders. Autoimmunity 38: 359-367.
    • (2005) Autoimmunity , vol.38 , pp. 359-367
    • Nishimoto, N.1
  • 17
    • 0036694589 scopus 로고    scopus 로고
    • IL-6 in autoimmune disease and chronic inflammatory proliferative disease
    • Ishihara, K., and T. Hirano. 2002. IL-6 in autoimmune disease and chronic inflammatory proliferative disease. Cytokine Growth Factor Rev. 13: 357-368.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 357-368
    • Ishihara, K.1    Hirano, T.2
  • 18
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira, S., K. Takeda, and T. Kaisho. 2001. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2: 675-680.
    • (2001) Nat. Immunol , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 20
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-κB activity
    • Karin, M., and Y. Ben-Neriah. 2000. Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu. Rev. Immunol. 18: 621-663.
    • (2000) Annu. Rev. Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 22
    • 0033012030 scopus 로고    scopus 로고
    • An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
    • Lutz, M. B., N. Kukutsch, A. L. Ogilvie, S. Rossner, F. Koch, N. Romani, and G. Schuler. 1999. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J. Immunol. Methods 223: 77-92.
    • (1999) J. Immunol. Methods , vol.223 , pp. 77-92
    • Lutz, M.B.1    Kukutsch, N.2    Ogilvie, A.L.3    Rossner, S.4    Koch, F.5    Romani, N.6    Schuler, G.7
  • 23
    • 0037033073 scopus 로고    scopus 로고
    • Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction
    • Latz, E., A. Visintin, E. Lien, K. A. Fitzgerald, B. G. Monks, E. A. Kurt-Jones, D. T. Golenbock, and T. Espevik. 2002. Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. J. Biol. Chem. 277: 47834-47843.
    • (2002) J. Biol. Chem , vol.277 , pp. 47834-47843
    • Latz, E.1    Visintin, A.2    Lien, E.3    Fitzgerald, K.A.4    Monks, B.G.5    Kurt-Jones, E.A.6    Golenbock, D.T.7    Espevik, T.8
  • 24
    • 0032488837 scopus 로고    scopus 로고
    • p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor
    • Vanden Berghe, W., S. Plaisance, E. Boone, K. De Bosscher, M. L. Schmitz, W. Fiers, and G. Haegeman. 1998. p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor. J. Biol. Chem. 273: 3285-3290.
    • (1998) J. Biol. Chem , vol.273 , pp. 3285-3290
    • Vanden Berghe, W.1    Plaisance, S.2    Boone, E.3    De Bosscher, K.4    Schmitz, M.L.5    Fiers, W.6    Haegeman, G.7
  • 25
    • 0030990093 scopus 로고    scopus 로고
    • Recombination signal sequence binding protein Jκ is constitutively bound to the NF-κB site of the interleukin-6 promoter and acts as a negative regulatory factor
    • Plaisance, S., W. Vanden Berghe, E. Boone, W. Fiers, and G. Haegeman. 1997. Recombination signal sequence binding protein Jκ is constitutively bound to the NF-κB site of the interleukin-6 promoter and acts as a negative regulatory factor. Mol. Cell. Biol. 17: 3733-3743.
    • (1997) Mol. Cell. Biol , vol.17 , pp. 3733-3743
    • Plaisance, S.1    Vanden Berghe, W.2    Boone, E.3    Fiers, W.4    Haegeman, G.5
  • 26
    • 0026535237 scopus 로고    scopus 로고
    • Unger, T., M. M. Nau, S. Segal, and J. D. Minna. 1992. p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer. EMBO J. 11: 1383-1390.
    • Unger, T., M. M. Nau, S. Segal, and J. D. Minna. 1992. p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer. EMBO J. 11: 1383-1390.
  • 27
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp, T. R., R. Bernards, and R. Agami. 2002. A system for stable expression of short interfering RNAs in mammalian cells. Science 296: 550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 28
    • 0037451357 scopus 로고    scopus 로고
    • Transcriptional activation of the NF-κB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)
    • Vermeulen, L., G. De Wilde, P. Van Damme, W. Vanden Berghe, and G. Haegeman. 2003. Transcriptional activation of the NF-κB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1). EMBO J. 22: 1313-1324.
    • (2003) EMBO J , vol.22 , pp. 1313-1324
    • Vermeulen, L.1    De Wilde, G.2    Van Damme, P.3    Vanden Berghe, W.4    Haegeman, G.5
  • 29
    • 0031459881 scopus 로고    scopus 로고
    • Glucocorticoid-mediated repression of nuclear factor-κB-dependent transcription involves direct interference with transactivation
    • De Bosscher, K., M. L. Schmitz, W. Vanden Berghe, S. Plaisance, W. Fiers, and G. Haegeman. 1997. Glucocorticoid-mediated repression of nuclear factor-κB-dependent transcription involves direct interference with transactivation. Proc. Natl. Acad. Sci. USA 94: 13504-13509.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13504-13509
    • De Bosscher, K.1    Schmitz, M.L.2    Vanden Berghe, W.3    Plaisance, S.4    Fiers, W.5    Haegeman, G.6
  • 30
    • 0027258123 scopus 로고
    • Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation
    • Verdin, E., P. Paras, Jr., and C. Van Lint. 1993. Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation. EMBO J. 12: 3249-3259.
    • (1993) EMBO J , vol.12 , pp. 3249-3259
    • Verdin, E.1    Paras Jr., P.2    Van Lint, C.3
  • 31
    • 0033570922 scopus 로고    scopus 로고
    • Interleukin-6 repression is associated with a distinctive chromatin structure of the gene
    • Amenante, F., M. Merola, A. Furia, M. Tovey, and M. Palmieri. 1999. Interleukin-6 repression is associated with a distinctive chromatin structure of the gene. Nucleic Acids Res. 27: 4483-4490.
    • (1999) Nucleic Acids Res , vol.27 , pp. 4483-4490
    • Amenante, F.1    Merola, M.2    Furia, A.3    Tovey, M.4    Palmieri, M.5
  • 32
    • 0037178777 scopus 로고    scopus 로고
    • Modifying gene expression programs by altering core promoter chromatin architecture
    • Lomvardas, S., and D. Thanos. 2002. Modifying gene expression programs by altering core promoter chromatin architecture. Cell 110: 261-271.
    • (2002) Cell , vol.110 , pp. 261-271
    • Lomvardas, S.1    Thanos, D.2
  • 33
    • 0036216109 scopus 로고    scopus 로고
    • Chromatin structure and gene regulation in the immune system
    • Smale, S. T., and A. G. Fisher. 2002. Chromatin structure and gene regulation in the immune system. Annu. Rev. Immunol. 20: 427-462.
    • (2002) Annu. Rev. Immunol , vol.20 , pp. 427-462
    • Smale, S.T.1    Fisher, A.G.2
  • 34
    • 32044439558 scopus 로고    scopus 로고
    • Selective and antagonistic functions of SWI/SNF and Mi-2β nucleosome remodeling complexes during an inflammatory response
    • Ramirez-Carrozzi, V. R., A. A. Nazarian, C. C. Li, S. L. Gore, R. Sridharan, A. N. Imbalzano, and S. T. Smale. 2006. Selective and antagonistic functions of SWI/SNF and Mi-2β nucleosome remodeling complexes during an inflammatory response. Genes Dev. 20: 282-296.
    • (2006) Genes Dev , vol.20 , pp. 282-296
    • Ramirez-Carrozzi, V.R.1    Nazarian, A.A.2    Li, C.C.3    Gore, S.L.4    Sridharan, R.5    Imbalzano, A.N.6    Smale, S.T.7
  • 36
    • 0033527448 scopus 로고    scopus 로고
    • The nuclear factor-κB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter
    • Vanden Berghe, W., K. De Bosscher, E. Boone, S. Plaisance, and G. Haegeman. 1999. The nuclear factor-κB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter. J. Biol. Chem. 274: 32091-32098.
    • (1999) J. Biol. Chem , vol.274 , pp. 32091-32098
    • Vanden Berghe, W.1    De Bosscher, K.2    Boone, E.3    Plaisance, S.4    Haegeman, G.5
  • 37
    • 23044498269 scopus 로고    scopus 로고
    • Inactivation of nuclear factor κB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells
    • Li, Y., F. Ahmed, S. Ali, P. A. Philip, O. Kucuk, and F. H. Sarkar. 2005. Inactivation of nuclear factor κB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells. Cancer Res. 65: 6934-6942.
    • (2005) Cancer Res , vol.65 , pp. 6934-6942
    • Li, Y.1    Ahmed, F.2    Ali, S.3    Philip, P.A.4    Kucuk, O.5    Sarkar, F.H.6
  • 39
    • 33645064160 scopus 로고    scopus 로고
    • Inhibition of nuclear factor κB activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells
    • Wang, Z., Y. Zhang, S. Banerjee, Y. Li, and F. H. Sarkar. 2006. Inhibition of nuclear factor κB activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells. Int. J. Cancer 118: 1930-1936.
    • (2006) Int. J. Cancer , vol.118 , pp. 1930-1936
    • Wang, Z.1    Zhang, Y.2    Banerjee, S.3    Li, Y.4    Sarkar, F.H.5
  • 40
    • 33748580218 scopus 로고    scopus 로고
    • Inhibition of proinflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: Analysis of the structure-activity relationship
    • Comalada, M., I. Ballester, E. Bailon, S. Sierra, J. Xaus, J. Galvez, F. S. Medina, and A. Zarzuelo. 2006. Inhibition of proinflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship. Biochem. Pharmacol. 72: 1010-1021.
    • (2006) Biochem. Pharmacol , vol.72 , pp. 1010-1021
    • Comalada, M.1    Ballester, I.2    Bailon, E.3    Sierra, S.4    Xaus, J.5    Galvez, J.6    Medina, F.S.7    Zarzuelo, A.8
  • 41
    • 0035022325 scopus 로고    scopus 로고
    • Effective antigen presentation by dendritic cells is NF-κB dependent: Coordinate regulation of MHC, co-stimulatory molecules and cytokines
    • Yoshimura, S., J. Bondeson, B. M. Foxwell, F. M. Brennan, and M. Feldmann. 2001. Effective antigen presentation by dendritic cells is NF-κB dependent: coordinate regulation of MHC, co-stimulatory molecules and cytokines. Int. Immunol. 13: 675-683.
    • (2001) Int. Immunol , vol.13 , pp. 675-683
    • Yoshimura, S.1    Bondeson, J.2    Foxwell, B.M.3    Brennan, F.M.4    Feldmann, M.5
  • 42
    • 0024238244 scopus 로고
    • Effect of genistein on topoisomerase activity and on the growth of [Val 12]Ha-ras-transformed NIH 3T3 cells
    • Okura, A., H. Arakawa, H. Oka, T. Yoshinari, and Y. Monden. 1988. Effect of genistein on topoisomerase activity and on the growth of [Val 12]Ha-ras-transformed NIH 3T3 cells. Biochem. Biophys. Res. Commun. 157: 183-189.
    • (1988) Biochem. Biophys. Res. Commun , vol.157 , pp. 183-189
    • Okura, A.1    Arakawa, H.2    Oka, H.3    Yoshinari, T.4    Monden, Y.5
  • 44
    • 0028948804 scopus 로고
    • Flavonoids as DNA topoisomerase antagonists and poisons: Structure-activity relationships
    • Constantinou, A., R. Mehta, C. Runyan, K. Rao, A. Vaughan, and R. Moon. 1995. Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships. J. Nat. Prod. 58: 217-225.
    • (1995) J. Nat. Prod , vol.58 , pp. 217-225
    • Constantinou, A.1    Mehta, R.2    Runyan, C.3    Rao, K.4    Vaughan, A.5    Moon, R.6
  • 45
    • 0842303315 scopus 로고    scopus 로고
    • The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX
    • Ye, R., A. A. Goodarzi, E. U. Kurz, S. Saito, Y. Higashimoto, M. F. Lavin, E. Appella, C. W. Anderson, and S. P. Lees-Miller. 2004. The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX. DNA Repair (Amst.). 3: 235-244.
    • (2004) DNA Repair (Amst.) , vol.3 , pp. 235-244
    • Ye, R.1    Goodarzi, A.A.2    Kurz, E.U.3    Saito, S.4    Higashimoto, Y.5    Lavin, M.F.6    Appella, E.7    Anderson, C.W.8    Lees-Miller, S.P.9
  • 47
    • 0028865771 scopus 로고
    • Triggering of the human interleukin-6 gene by interferon-γ and tumor necrosis factor-α in monocytic cells involves cooperation between interferon regulatory factor-1, NF κB, and Sp1 transcription factors
    • Sanceau, J., T. Kaisho, T. Hirano, and J. Wietzerbin. 1995. Triggering of the human interleukin-6 gene by interferon-γ and tumor necrosis factor-α in monocytic cells involves cooperation between interferon regulatory factor-1, NF κB, and Sp1 transcription factors. J. Biol. Chem. 270: 27920-27931.
    • (1995) J. Biol. Chem , vol.270 , pp. 27920-27931
    • Sanceau, J.1    Kaisho, T.2    Hirano, T.3    Wietzerbin, J.4
  • 48
    • 0029979531 scopus 로고    scopus 로고
    • Binding and functional effects of transcriptional factor Sp1 on the murine interleukin-6 promoter
    • Kang, S. H., D. A. Brown, I. Kitajima, X. Xu, O. Heidenreich, S. Gryaznov, and M. Nerenberg. 1996. Binding and functional effects of transcriptional factor Sp1 on the murine interleukin-6 promoter. J. Biol. Chem. 271: 7330-7335.
    • (1996) J. Biol. Chem , vol.271 , pp. 7330-7335
    • Kang, S.H.1    Brown, D.A.2    Kitajima, I.3    Xu, X.4    Heidenreich, O.5    Gryaznov, S.6    Nerenberg, M.7
  • 49
    • 0032954928 scopus 로고    scopus 로고
    • Transcriptional cross talk between NF-κB and p53
    • Webster, G. A., and N. D. Perkins. 1999. Transcriptional cross talk between NF-κB and p53. Mol. Cell. Biol. 19: 3485-3495.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 3485-3495
    • Webster, G.A.1    Perkins, N.D.2
  • 51
    • 0036247821 scopus 로고    scopus 로고
    • p53-Mdm2: The affair that never ends
    • Alarcon-Vargas, D., and Z. Ronai. 2002. p53-Mdm2: the affair that never ends. Carcinogenesis 23: 541-547.
    • (2002) Carcinogenesis , vol.23 , pp. 541-547
    • Alarcon-Vargas, D.1    Ronai, Z.2
  • 52
    • 24944458421 scopus 로고    scopus 로고
    • Genistein, a dietary isoflavone, down-regulates the MDM2 oncogene at both transcriptional and posttranslational levels
    • Li, M., Z. Zhang, D. L. Hill, X. Chen, H. Wang, and R. Zhang. 2005. Genistein, a dietary isoflavone, down-regulates the MDM2 oncogene at both transcriptional and posttranslational levels. Cancer Res. 65: 8200-8208.
    • (2005) Cancer Res , vol.65 , pp. 8200-8208
    • Li, M.1    Zhang, Z.2    Hill, D.L.3    Chen, X.4    Wang, H.5    Zhang, R.6
  • 53
    • 17844392396 scopus 로고    scopus 로고
    • Tumor suppressor p53 inhibits autoimmune inflammation and macrophage function
    • Zheng, S. J., S. E. Lamhamedi-Cherradi, P. Wang, L. Xu, and Y. H. Chen. 2005. Tumor suppressor p53 inhibits autoimmune inflammation and macrophage function. Diabetes 54: 1423-1428.
    • (2005) Diabetes , vol.54 , pp. 1423-1428
    • Zheng, S.J.1    Lamhamedi-Cherradi, S.E.2    Wang, P.3    Xu, L.4    Chen, Y.H.5
  • 55
    • 0036469114 scopus 로고    scopus 로고
    • Autocrine interleukin-6 production in renal cell carcinoma: Evidence for the involvement of p53
    • Angelo, L. S., M. Talpaz, and R. Kurzrock. 2002. Autocrine interleukin-6 production in renal cell carcinoma: evidence for the involvement of p53. Cancer Res. 62: 932-940.
    • (2002) Cancer Res , vol.62 , pp. 932-940
    • Angelo, L.S.1    Talpaz, M.2    Kurzrock, R.3
  • 58
    • 0034628544 scopus 로고    scopus 로고
    • Overexpression of the wild-type p53 gene inhibits NF-κB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells
    • Shao, J., T. Fujiwara, Y. Kadowaki, T. Fukazawa, T. Waku, T. Itoshima, T. Yamatsuji, M. Nishizaki, J. A. Roth, and N. Tanaka. 2000. Overexpression of the wild-type p53 gene inhibits NF-κB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells. Oncogene 19: 726-736.
    • (2000) Oncogene , vol.19 , pp. 726-736
    • Shao, J.1    Fujiwara, T.2    Kadowaki, Y.3    Fukazawa, T.4    Waku, T.5    Itoshima, T.6    Yamatsuji, T.7    Nishizaki, M.8    Roth, J.A.9    Tanaka, N.10
  • 59
    • 4444226454 scopus 로고    scopus 로고
    • HTLV-1 Tax induces a novel interaction between p65/RelA and p53 that results in inhibition of p53 transcriptional activity
    • Jeong, S. J., M. Radonovich, J. N. Brady, and C. A. Pise-Masison. 2004. HTLV-1 Tax induces a novel interaction between p65/RelA and p53 that results in inhibition of p53 transcriptional activity. Blood 104: 1490-1497.
    • (2004) Blood , vol.104 , pp. 1490-1497
    • Jeong, S.J.1    Radonovich, M.2    Brady, J.N.3    Pise-Masison, C.A.4
  • 61
    • 3142545770 scopus 로고    scopus 로고
    • DNA damage induces p53-dependent BRCA1 nuclear export
    • Feng, Z., L. Kachnic, J. Zhang, S. N. Powell, and F. Xia. 2004. DNA damage induces p53-dependent BRCA1 nuclear export. J. Biol. Chem. 279: 28574-28584.
    • (2004) J. Biol. Chem , vol.279 , pp. 28574-28584
    • Feng, Z.1    Kachnic, L.2    Zhang, J.3    Powell, S.N.4    Xia, F.5
  • 62
    • 0035691870 scopus 로고    scopus 로고
    • Regulation of functional nuclear pore size in fibroblasts
    • Feldherr, C. M., D. Akin, and R. J. Cohen. 2001. Regulation of functional nuclear pore size in fibroblasts. J. Cell Sci. 114: 4621-4627.
    • (2001) J. Cell Sci , vol.114 , pp. 4621-4627
    • Feldherr, C.M.1    Akin, D.2    Cohen, R.J.3
  • 63
    • 0027244682 scopus 로고
    • Modulation of the human interleukin-6 promoter (IL-6) and transcription factor C/EBPβ (NF-IL6) activity by p53 species
    • Margulies, L., and P. B. Sehgal. 1993. Modulation of the human interleukin-6 promoter (IL-6) and transcription factor C/EBPβ (NF-IL6) activity by p53 species. J. Biol. Chem. 268: 15096-15100.
    • (1993) J. Biol. Chem , vol.268 , pp. 15096-15100
    • Margulies, L.1    Sehgal, P.B.2
  • 64
    • 0032965204 scopus 로고    scopus 로고
    • Differential regulation of IL-6 promoter activity in a human ovarian-tumor cell line transfected with various p53 mutants: Involvement of AP-1
    • Asschert, J. G., E. G. De Vries, S. De Jong, S. Withoff, and E. Vellenga. 1999. Differential regulation of IL-6 promoter activity in a human ovarian-tumor cell line transfected with various p53 mutants: involvement of AP-1. Int. J. Cancer 81: 236-242.
    • (1999) Int. J. Cancer , vol.81 , pp. 236-242
    • Asschert, J.G.1    De Vries, E.G.2    De Jong, S.3    Withoff, S.4    Vellenga, E.5
  • 67
    • 1842732225 scopus 로고    scopus 로고
    • A defect in nucleosome remodeling prevents IL-12(p35) gene transcription in neonatal dendritic cells
    • Goriely, S., C. Van Lint, R. Dadkhah, M. Libin, D. De Wit, D. Demonte, F. Willems, and M. Goldman. 2004. A defect in nucleosome remodeling prevents IL-12(p35) gene transcription in neonatal dendritic cells. J. Exp. Med. 199: 1011-1016.
    • (2004) J. Exp. Med , vol.199 , pp. 1011-1016
    • Goriely, S.1    Van Lint, C.2    Dadkhah, R.3    Libin, M.4    De Wit, D.5    Demonte, D.6    Willems, F.7    Goldman, M.8
  • 68
    • 4344610526 scopus 로고    scopus 로고
    • Small-molecule antagonists of p53-MDM2 binding: Research tools and potential therapeutics
    • Vassilev, L. T. 2004. Small-molecule antagonists of p53-MDM2 binding: research tools and potential therapeutics. Cell Cycle 3: 419-421.
    • (2004) Cell Cycle , vol.3 , pp. 419-421
    • Vassilev, L.T.1


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