Fis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesis

Experimental Cell Research

Volumn 313, Issue 8, 2007, Pages 1675-1686

  Kobayashi, Shinta ^a   Tanaka, Atsushi ^a   Fujiki, Yukio ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

CHO cell mutant; Dynamin like protein 1 (DLP1); Fis1; Peroxisome abundance; Peroxisome morphogenesis; Pex11p

Indexed keywords

COMPLEMENTARY DNA; DYNAMIN LIKE PROTEIN 1; FIS1 PROTEIN; MEMBRANE PROTEIN; PEX11PBETA PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CELL PROLIFERATION; CHO CELL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CROSS LINKING; DNA TRANSFECTION; FLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; MITOCHONDRION; MORPHOGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PEROXISOME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

MAMMALIA;

EID: 34247107180     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2007.02.028     Document Type: Article

References (40)

1. van den Bosch H., Schutgens R.B.H., Wanders R.J.A., and Tager J.M. Biochemistry of peroxisomes. Annu. Rev. Biochem. 61 (1992) 157-197
2. Gould S.J., and Valle D. Peroxisome biogenesis disorders: genetics and cell biology. Trends Genet. 16 (2000) 340-345
3. Matsumoto N., Tamura S., and Fujiki Y. The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes. Nat. Cell Biol. 5 (2003) 454-460
4. Shimozawa N., Tsukamoto T., Nagase T., Takemoto Y., Koyama N., Suzuki Y., Komori M., Osumi T., Jeannette G., Wanders R.J.A., and Kondo N. Identification of a new complementation group of the peroxisome biogenesis disorders and PEX14 as the mutated gene. Human Mutat. 23 (2004) 552-558
5. Fujiki Y. Peroxisome biogenesis and peroxisome biogenesis disorders. FEBS Lett. 476 (2000) 42-46
6. Sacksteder K.A., and Gould S.J. The genetics of peroxisome biogenesis. Annu. Rev. Genet. 34 (2000) 623-652
7. Fujiki Y. Peroxisome biogenesis disorders. In: Cooper D.N. (Ed). Nature Encyclopedia of the Human Genome (2003), Nature Publishing Group, London
8. Purdue P.E., and Lazarow P.B. Peroxisome biogenesis. Annu. Rev. Cell Dev. Biol. 17 (2001) 701-752
9. Titorenko V.I., and Rachubinski R.A. The life cycle of the peroxisome. Nat. Rev., Mol. Cell Biol. 2 (2001) 357-368
10. Heiland I., and Erdmann R. Biogenesis of peroxisomes: topogenesis of the peroxisomal membrane and matrix proteins. FEBS J. 272 (2005) 2362-2372
11. Yan M., Rayapuram N., and Subramani S. The control of peroxisome number and size during division and proliferation. Curr. Opin. Cell Biol. 17 (2005) 376-383
12. Abe I., and Fujiki Y. cDNA cloning and characterization of a constitutively expressed isoform of the human peroxin Pex11p. Biochem. Biophys. Res. Commun. 252 (1998) 529-533
13. Schrader M., Reuber B.E., Morrell J.C., Jimenez-Sanchez G., Obie C., Stroh T.A., Valle D., Schroer T.A., and Gould S.J. Expression of PEX11β mediates peroxisome proliferation in the absence of extracellular stimuli. J. Biol. Chem. 273 (1998) 29607-29614
14. Li X., and Gould S.J. PEX11 promotes peroxisome division independently of peroxisome metabolism. J. Cell Biol. 156 (2002) 643-651
15. Li X., Baumgart E., Morrell J.C., Jimenez-Sanchez G., Valle D., and Gould S.J. PEX11b deficiency is lethal and impairs neuronal migration but does not abrogate peroxisome function. Mol. Cell. Biol. 22 (2002) 4358-4365
16. Koch A., Thiemann M., Grabenbauer M., Yoon Y., McNiven M.A., and Schrader M. Dynamin-like protein 1 is involved in peroxisomal fission. J. Biol. Chem. 278 (2003) 8597-8605
17. Li X., and Gould S.J. The dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11. J. Biol. Chem. 278 (2003) 17012-17020
18. Tanaka A., Kobayashi S., and Fujiki Y. Peroxisome division is impaired in a CHO cell mutant with an inactivating point-mutation in dynamin-like protein 1 gene. Exp. Cell Res. 312 (2006) 1671-1684
19. Yoon Y., Krueger E.W., Oswald B.J., and McNiven M.A. The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1. Mol. Cell. Biol. 23 (2003) 5409-5420
20. James D.I., Parone P.A., Mattenberger Y., and Martinou J.-C. hFis1, a novel component of the mammalian mitochondrial fission machinery. J. Biol. Chem. 278 (2003) 36373-36379
21. Stojanovski D., Koutsopoulos O.S., Okamoto K., and Ryan M.T. Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology. J. Cell Sci. 117 (2004) 1201-1210
22. Koch A., Yoon Y., Bonekamp N.A., McNiven M.A., and Schrader M. A role for Fis1 in both mitochondrial and peroxisomal fission in mammalian cells. Mol. Biol. Cell 16 (2005) 5077-5086
23. Otera H., Okumoto K., Tateishi K., Ikoma Y., Matsuda E., Nishimura M., Tsukamoto T., Osumi T., Ohashi K., Higuchi O., and Fujiki Y. Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: studies with PEX5-defective CHO cell mutants. Mol. Cell. Biol. 18 (1998) 388-399
24. Shimizu N., Itoh R., Hirono Y., Otera H., Ghaedi K., Tateishi K., Tamura S., Okumoto K., Harano T., Mukai S., and Fujiki Y. The peroxin Pex14p: cDNA cloning by functional complementation on a Chinese hamster ovary cell mutant, characterization, and functional analysis. J. Biol. Chem. 274 (1999) 12593-12604
25. Tsukamoto T., Yokota S., and Fujiki Y. Isolation and characterization of Chinese hamster ovary cell mutants defective in assembly of peroxisomes. J. Cell Biol. 110 (1990) 651-660
26. Kawajiri K., Harano T., and Omura T. Biogenesis of the mitochondrial matrix enzyme, glutamate dehydrogenase, in rat liver cells. I. Subcellular localization, biosynthesis, and intracellular translocation of glutamate dehydrogenase. J. Biochem. 82 (1977) 1403-1416
27. Otera H., Harano T., Honsho M., Ghaedi K., Mukai S., Tanaka A., Kawai A., Shimizu N., and Fujiki Y. The mammalian peroxin Pex5pL, the longer isoform of the mobile PTS1-transporter, translocates Pex7p-PTS2 protein complex into peroxisomes via its initial docking site Pex14p. J. Biol. Chem. 275 (2000) 21703-21714
28. Mukai S., Ghaedi K., and Fujiki Y. Intracellular localization, function, and dysfunction of the peroxisome-targeting signal type 2 receptor, Pex7p, in mammalian cells. J. Biol. Chem. 277 (2002) 9548-9561
29. Ghaedi K., Itagaki A., Toyama R., Tamura S., Matsumura T., Kawai A., Shimozawa N., Suzuki Y., Kondo N., and Fujiki Y. Newly identified Chinese hamster ovary cell mutants defective in peroxisome assembly represent complementation group A of human peroxisome biogenesis disorders and one novel group in mammals. Exp. Cell Res. 248 (1999) 482-488
30. Otera H., Setoguchi K., Hamasaki M., Kumashiro T., Shimizu N., and Fujiki Y. Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import. Mol. Cell. Biol. 22 (2002) 1639-1655
31. Donze O., and Picard D. RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res. 30 (2002) e46
32. Tamura S., Yasutake S., Matsumoto N., and Fujiki Y. Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p. J. Biol. Chem. 281 (2006) 27693-27704
33. Tsuchida K., Vaughan J.M., Wiater E., Gaddy-Kurten D., and Vale W.W. Inactivation of activin-dependent transcription by kinase-deficient activin receptors. Endocrinology 136 (1995) 5493-5503
34. Fujiki Y., Hubbard A.L., Fowler S., and Lazarow P.B. Isolation of intracellular membranes by means of sodium carbonate treatment: application to endoplasmic reticulum. J. Cell Biol. 93 (1982) 97-102
35. Okumoto K., Shimozawa N., Kawai A., Tamura S., Tsukamoto T., Osumi T., Moser H., Wanders R.J.A., Suzuki Y., Kondo N., and Fujiki Y. PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of Pex12p. Mol. Cell. Biol. 18 (1998) 4324-4336
36. Fekkesa P., Sheparda K.A., and Yaffe M.P. Gag3p, an outer membrane protein required for fission of mitochondrial tubules. J. Cell Biol. 151 (2000) 333-340
37. Yoon Y., Pitts K.R., and McNiven M.A. Mammalian dynamin-like protein DLP1 tubulates membranes. Mol. Biol. Cell 12 (2001) 2894-2905
38. Smirnova E., Griparic L., Shurland D.L., and van der Bliek A.M. Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol. Biol. Cell 12 (2001) 2245-2256
39. Tieu Q., and Nunnari J. Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division. J. Cell Biol. 151 (2000) 353-366
40. Schrader M. Shared components of mitochondrial and peroxisomal division. Biochim. Biophys. Acta 1763 (2006) 531-541