Histone deacetylase inhibitor trichostatin a potentiates doxorubicin-induced apoptosis by up-regulating PTEN expression

Cancer

Volumn 109, Issue 8, 2007, Pages 1676-1688

  Pan, Lina ^a   Lu, Jun ^a   Wang, Xiuli ^a   Han, Liping ^a   Zhang, Yu ^a   Han, Songyan ^a   Huang, Baiqu ^a  

^a NORTHEAST NORMAL UNIVERSITY   (China)

Author keywords

Apoptosis; Doxorubicin; Egr 1; Histone acetylation; PTEN; siRNA

Indexed keywords

ADENOVIRUS VECTOR; DOXORUBICIN; EARLY GROWTH RESPONSE FACTOR 1; HISTONE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE INHIBITOR; HOE 33342; LUCIFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN P300; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRICHOSTATIN A;

ACETYLATION; APOPTOSIS; ARTICLE; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; TUMOR SUPPRESSOR GENE; UPREGULATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; DOXORUBICIN; EARLY GROWTH RESPONSE PROTEIN 1; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; IMMUNOPRECIPITATION; PROMOTER REGIONS (GENETICS); PTEN PHOSPHOHYDROLASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION; UP-REGULATION;

EID: 34247107123     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.22585     Document Type: Article

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