Severely impaired neuromuscular synaptic transmission causes muscle weakness in the Cacna1a-mutant mouse rolling Nagoya

European Journal of Neuroscience

Volumn 25, Issue 7, 2007, Pages 2009-2020

  Kaja, Simon ^a,c   Van De Ven, Rob C G ^a   Van Dijk, J Gert ^a   Verschuuren, Jan J G M ^a   Arahata, Kiichi ^b   Frants, Rune R ^a   Ferrari, Michel D ^a   Van Den Maagdenberg, Arn M J M ^a   Plomp, Jaap J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Acetylcholine release; Cav2.1 channel; CACNA1A mutation; Electromyography; Electrophysiology; Neuromuscular junction

Indexed keywords

ACETYLCHOLINE; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; GENE PRODUCT; NEUROTRANSMITTER; PROTEIN CACNA1A; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATAXIA; COMPARATIVE STUDY; CONTROLLED STUDY; DIAPHRAGM; DISEASE SEVERITY; EATON LAMBERT SYNDROME; ELECTROMYOGRAPHY; EVOKED RESPONSE; FEMALE; GAIT DISORDER; GRIP STRENGTH; MALE; MOUSE; MOUSE MUTANT; MUSCLE; MUSCLE CONTRACTILITY; MUSCLE FATIGUE; MUSCLE WEAKNESS; NERVE STIMULATION; NEUROMUSCULAR DISEASE; NEUROMUSCULAR FUNCTION; NEUROMUSCULAR SYNAPSE; NEUROTRANSMITTER RELEASE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SOLEUS MUSCLE; WILD TYPE;

ACETYLCHOLINE; ANIMALS; ATAXIA; CALCIUM CHANNELS, P-TYPE; CALCIUM CHANNELS, Q-TYPE; ELECTROMYOGRAPHY; HUMANS; MICE; MICE, MUTANT STRAINS; MUSCLE CONTRACTION; MUSCLE FATIGUE; MUSCLE FIBERS; MUSCLE WEAKNESS; MUSCLE, SKELETAL; NEUROMUSCULAR JUNCTION; POINT MUTATION; SYNAPTIC TRANSMISSION;

EID: 34147214747     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.05438.x     Document Type: Article

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