Gene dosage-dependent transmitter release changes at neuromuscular synapses of Cacna1a R192Q knockin mice are non-progressive and do not lead to morphological changes or muscle weakness

Neuroscience

Volumn 135, Issue 1, 2005, Pages 81-95

  Kaja, S ^a   Van De Ven, R C G ^b   Broos, L A M ^b   Veldman, H ^c   Van Dijk, J G ^a   Verschuuren, J J G M ^a   Frants, R R ^b   Ferrari, M D ^a   Van Den Maagdenberg, A M J M ^a,b   Plomp, J J ^a,b  

^a Department of Neurology and Clinical Neurophysiology ^*  (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Cav2.1 mutation; CACNA1A; Migraine; Neuromuscular junction; Neurotransmitter release

Indexed keywords

ACETYLCHOLINE; CALCIUM CHANNEL; CALCIUM ION; NEUROTRANSMITTER;

ACETYLCHOLINE RELEASE; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CACNA1A GENE; CALCIUM TRANSPORT; CONCENTRATION (PARAMETERS); ELECTROMYOGRAPHY; EVOKED RESPONSE; FEMALE; GENE; GENE DOSAGE; GRIP STRENGTH; HYPOTHESIS; KNOCKOUT MOUSE; MALE; MORPHOLOGY; MOUSE; MUSCLE CONTRACTION; MUSCLE WEAKNESS; NERVE STIMULATION; NEUROMUSCULAR SYNAPSE; NEUROTRANSMITTER RELEASE; NONHUMAN; PARAMETER; PRESYNAPTIC NERVE; PRIORITY JOURNAL; ULTRASTRUCTURE;

ACETYLCHOLINE; AGING; ANIMALS; APOPTOSIS; BUNGAROTOXINS; CALCIUM CHANNELS, P-TYPE; CALCIUM CHANNELS, Q-TYPE; COLORING AGENTS; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; ELECTROPHYSIOLOGY; GENE DOSAGE; HAND STRENGTH; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; MUSCLE CONTRACTION; MUSCLE WEAKNESS; NEUROMUSCULAR JUNCTION; NEUROTRANSMITTER AGENTS; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 24044458609     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2005.04.069     Document Type: Article

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