Studies of arginine metabolism and salt sensitivity in the Dahl/Rapp rat models of hypertension

Molecular Genetics and Metabolism

Volumn 64, Issue 1, 1998, Pages 80-83

  Wood, Philip A ^a   Hamm, Doug A ^a   Chen, Pei Yan ^b,c,d   Sanders, Paul W ^b,c,d  

^a UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d BIRMINGHAM VA MEDICAL CENTER   (United States)

Author keywords

Arginine metabolism; Argininosuccinate synthetase; Dahl Rapp rat models; Hypertension

Indexed keywords

ARGININE;

AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; ANIMAL MODEL; ARTICLE; HYPERTENSION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SALT INTAKE; UREA CYCLE;

ANIMALIA;

EID: 0032073596     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1006/mgme.1998.2696     Document Type: Article

References (8)

1. Chen P Y, Sanders P W. L. J Clin Invest. 88:1991;1559-1567.
2. Chen P Y, St. John PL, Kirk KA, Abrahamson DR, Sanders PW. Hypertensive nephrosclerosis in the Dahl/Rapp rat. Lab Invest. 68:1993;174-184.
3. Chen P Y, Sanders P W. Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats. Hypertension. 22:1993;812-818.
4. Morris S M. Regulation of enzymes of urea and arginine synthesis. Ann Rev Nutr. 12:1992;81-101.
5. Nuzum C T, Snodgrass P J. Urea cycle enzyme adaption to dietary protein in primates. Science. 172:1971;1042-1043.
6. Brusilow S W, Horwich A L. Urea cycle enzymes. The Metabolic and Molecular Bases of Inherited Disease. 1995;McGraw-Hill, New York. p. 1187-1232.
7. Nuzum C T, Snodgrass P J. Multiple assays of the 5 urea cycle enzymes in human liver homogenates. Grisoli S, Baguena R, Mayor F. The Urea Cycle. 1976;325-349 Wiley, New York.
8. Chen P Y, Gladish R D, Sanders P W. Vascular smooth muscle nitric oxide synthase anomalies in Dahl/Rapp salt-sensitive rats. Hypertension. 31:1998;918-924.