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Volumn 75, Issue 4, 2007, Pages 1738-1744

Interleukin-12 drives the Th1 signaling pathway in Helicobacter pylori-infected human gastric mucosa

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4; STAT4 PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TBX5;

EID: 34147166091     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01446-06     Document Type: Article
Times cited : (47)

References (28)
  • 5
    • 0028012527 scopus 로고
    • Interleukin-12
    • Brunda, M. J. 1994. Interleukin-12. J. Leukoc. Biol. 55:280-288.
    • (1994) J. Leukoc. Biol , vol.55 , pp. 280-288
    • Brunda, M.J.1
  • 6
    • 0030469719 scopus 로고    scopus 로고
    • Activation of STAT4 by IL-12 and IFN-alpha: Evidence for the involvement of ligand-induced tyrosine and serine phosphorylation
    • Cho, S. S., C. M. Bacon, C. Sudarshan, R. C. Rees, D. Finbloom, R. Pine, and J. J. O'Shea. 1996. Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation. J. Immunol. 157:4781-4789.
    • (1996) J. Immunol , vol.157 , pp. 4781-4789
    • Cho, S.S.1    Bacon, C.M.2    Sudarshan, C.3    Rees, R.C.4    Finbloom, D.5    Pine, R.6    O'Shea, J.J.7
  • 7
    • 0031567981 scopus 로고    scopus 로고
    • T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease
    • D'Elios, M. M., M. Manghetti, M. De Carli, F. Costa, C. T. Baldari, D. Burroni, J. L. Telford, and S. Romagnani. 1997. T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease. J. Immunol. 158:962-967.
    • (1997) J. Immunol , vol.158 , pp. 962-967
    • D'Elios, M.M.1    Manghetti, M.2    De Carli, M.3    Costa, F.4    Baldari, C.T.5    Burroni, D.6    Telford, J.L.7    Romagnani, S.8
  • 8
    • 0013575179 scopus 로고    scopus 로고
    • Dixon, M. F., R. M. Genta, J. H. Yardley, and P. Correa. 1996. Classification and grading of gastritis. The updated Sydney System, International Workshop on the histopathology of gastritis, Houston. Am. J. Surg. Pathol. 20: 1161-1181.
    • Dixon, M. F., R. M. Genta, J. H. Yardley, and P. Correa. 1996. Classification and grading of gastritis. The updated Sydney System, International Workshop on the histopathology of gastritis, Houston. Am. J. Surg. Pathol. 20: 1161-1181.
  • 9
    • 0032555904 scopus 로고    scopus 로고
    • A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cells
    • Kaplan, M. H., A. L. Wurster, and M. J. Grusby. 1998. A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cells. J. Exp. Med. 188:1191-1196.
    • (1998) J. Exp. Med , vol.188 , pp. 1191-1196
    • Kaplan, M.H.1    Wurster, A.L.2    Grusby, M.J.3
  • 10
    • 0028913117 scopus 로고
    • Interferon gamma and interleukin 4 secreting cells in the gastric antrum in Helicobacter pylori positive and negative gastritis
    • Karttunen, R., T. Karttunen, H. P. Ekre, and T. T. MacDonald. 1995. Interferon gamma and interleukin 4 secreting cells in the gastric antrum in Helicobacter pylori positive and negative gastritis. Gut 36:341-345.
    • (1995) Gut , vol.36 , pp. 341-345
    • Karttunen, R.1    Karttunen, T.2    Ekre, H.P.3    MacDonald, T.T.4
  • 11
    • 2442711457 scopus 로고    scopus 로고
    • Early target genes of IL-12 and STAT4 signaling in Th cells
    • Lund, R. J., Z. Chen, J. Scheinin, and R. Lahesmaa. 2004. Early target genes of IL-12 and STAT4 signaling in Th cells. J. Immunol. 172:6775-6782.
    • (2004) J. Immunol , vol.172 , pp. 6775-6782
    • Lund, R.J.1    Chen, Z.2    Scheinin, J.3    Lahesmaa, R.4
  • 12
    • 0030938148 scopus 로고    scopus 로고
    • Regulation of transforming growth factor-beta production by interleukin-12
    • Marth, T., W. Strober, R. A. Seder, and B. L. Kelsall. 1997. Regulation of transforming growth factor-beta production by interleukin-12. Eur. J. Immunol. 27:1213-1220.
    • (1997) Eur. J. Immunol , vol.27 , pp. 1213-1220
    • Marth, T.1    Strober, W.2    Seder, R.A.3    Kelsall, B.L.4
  • 13
    • 0033564668 scopus 로고    scopus 로고
    • Extinction of IL-12 signaling promotes Fas-mediated apoptosis of antigen-specific T cells
    • Marth, T., M. Zeitz, B. R. Ludviksson, W. Strober, and B. L. Kelsall. 1999. Extinction of IL-12 signaling promotes Fas-mediated apoptosis of antigen-specific T cells. J. Immunol. 162:7233-7240.
    • (1999) J. Immunol , vol.162 , pp. 7233-7240
    • Marth, T.1    Zeitz, M.2    Ludviksson, B.R.3    Strober, W.4    Kelsall, B.L.5
  • 14
    • 0028329177 scopus 로고
    • Effects of IL-12 on helper T cell-dependent immune responses in vivo
    • McKnight, A. J., G. J. Zimmer, I. Fogelman, S. F. Wolf, and A. K. Abba. 1994. Effects of IL-12 on helper T cell-dependent immune responses in vivo. J. Immunol. 152:2172-2179.
    • (1994) J. Immunol , vol.152 , pp. 2172-2179
    • McKnight, A.J.1    Zimmer, G.J.2    Fogelman, I.3    Wolf, S.F.4    Abba, A.K.5
  • 16
    • 0036885067 scopus 로고    scopus 로고
    • The lineage decisions of helper T cells
    • Murphy, K. M., and S. L. Reiner. 2002. The lineage decisions of helper T cells. Nat. Rev. Immunol. 2:933-944.
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 933-944
    • Murphy, K.M.1    Reiner, S.L.2
  • 17
    • 0037108385 scopus 로고    scopus 로고
    • Activated STAT4 has an essential role in Th1 differentiation and proliferation that is independent of its role in the maintenance of IL-12R beta 2 chain expression and signaling
    • Nishikomori, R., T. Usui, C. Y. Wu, A. Morinobu, J. J. O'Shea, and W. Strober. 2002. Activated STAT4 has an essential role in Th1 differentiation and proliferation that is independent of its role in the maintenance of IL-12R beta 2 chain expression and signaling. J. Immunol. 169:4388-4398.
    • (2002) J. Immunol , vol.169 , pp. 4388-4398
    • Nishikomori, R.1    Usui, T.2    Wu, C.Y.3    Morinobu, A.4    O'Shea, J.J.5    Strober, W.6
  • 21
    • 8044250881 scopus 로고    scopus 로고
    • Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells
    • Szabo, S. J., A. S. Dighe, U. Gubler, and K. M. Murphy. 1997. Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J. Exp. Med. 185:817-824.
    • (1997) J. Exp. Med , vol.185 , pp. 817-824
    • Szabo, S.J.1    Dighe, A.S.2    Gubler, U.3    Murphy, K.M.4
  • 23
    • 0037059462 scopus 로고    scopus 로고
    • Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells
    • Szabo, S. J., B. M. Sullivan, C. Stemmann, A. R. Satoskar, B. P. Sleckman, and L. H. Glimcher. 2002. Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science 295: 338-342.
    • (2002) Science , vol.295 , pp. 338-342
    • Szabo, S.J.1    Sullivan, B.M.2    Stemmann, C.3    Satoskar, A.R.4    Sleckman, B.P.5    Glimcher, L.H.6
  • 24
    • 0030949167 scopus 로고    scopus 로고
    • STAT6: Its role in interleukin 4-mediated biological functions
    • Takeda, K., T. Kishimoto, and S. Akira. 1997. STAT6: its role in interleukin 4-mediated biological functions. J. Mol. Med. 75:317-326.
    • (1997) J. Mol. Med , vol.75 , pp. 317-326
    • Takeda, K.1    Kishimoto, T.2    Akira, S.3
  • 26
    • 0028043326 scopus 로고
    • Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
    • Trinchieri, G. 1994. Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes. Blood 84:4008-4027.
    • (1994) Blood , vol.84 , pp. 4008-4027
    • Trinchieri, G.1
  • 28
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
    • Zheng, W., and R. A. Flavell. 1997. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89:587-596.
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.1    Flavell, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.