Regulator of G-protein signalling 3 redirects prototypical Gi-coupled receptors from Rac1 to RhoA activation

Cellular Signalling

Volumn 19, Issue 6, 2007, Pages 1229-1237

  Vogt, Andreas ^a   Lutz, Susanne ^a   Rümenapp, Ulrich ^b   Han, Li ^b   Jakobs, Karl H ^b   Schmidt, Martina ^b   Wieland, Thomas ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

FGF 2; G dimers; Gi proteins; Rac1; RGS proteins; RGS3; RhoA

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADENOSINE A1 RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; AMINO ACID; DIMER; FIBROBLAST GROWTH FACTOR 2; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; GUANOSINE TRIPHOSPHATASE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPROTEIN; MUSCARINIC M2 RECEPTOR; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN RGS3L; RAC1 PROTEIN; RGS PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL STRAIN; CONTROLLED STUDY; DIMERIZATION; EMBRYO; ENZYME ACTIVATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALANINE; ANIMALS; ASPARAGINE; CARBACHOL; CELL LINE; DIMERIZATION; DOWN-REGULATION; ENZYME ACTIVATION; FIBROBLAST GROWTH FACTOR 2; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; GTP-BINDING PROTEINS; GTPASE-ACTIVATING PROTEINS; HUMANS; MUTANT PROTEINS; RAC1 GTP-BINDING PROTEIN; RATS; RECEPTORS, G-PROTEIN-COUPLED; RHOA GTP-BINDING PROTEIN; RNA, SMALL INTERFERING; SERUM RESPONSE FACTOR; STRESS FIBERS;

RATTUS;

EID: 34147165024     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2007.01.003     Document Type: Article

References (43)

1. Etienne-Manneville S., and Hall A. Nature 420 (2002) 629
2. Burridge K., and Wennerberg K. Cell 116 (2004) 167
3. Brown J.H., Del Re D.P., and Sussman M.A. Circ. Res. 98 (2006) 730
4. Rossman K., Der C., and Sondek J. Nat. Rev., Mol. Cell Biol. 6 (2005) 167
5. Wieland T., and Mittmann C. Pharmacol. Ther. 97 (2003) 95
6. Riddle E.L., Schwartzman R.A., Bond M., and Insel P.A. Circ. Res. 96 (2005) 401
7. Abramow-Newerly M., Roy A.A., Nunn C., and Chidiac P. Cell. Signal. 18 (2006) 579
8. Scheschonka A., Dessauer C., Sinnarajah S., Chidiac P., Shi C., and Kehrl J.H. Mol. Pharmacol. 58 (2000) 719
9. Owen V.J., Burton P.B., Mullen A.J., Birks E.J., Barton P., and Yacoub M.H. Eur. Heart J. 22 (2001) 1015
10. Mittmann C., Chung C.H., Höppner G., Michalek C., Nose M., Schüler C., Schuh A., Eschenhagen T., Weil J., Pieske B., Hirt S., and Wieland T. Cardiovasc. Res. 55 (2002) 778
11. Mittmann C., Schüler C., Chung C.H., Höppner G., Nose M., Kehrl J.H., and Wieland T. Naunyn-Schmiedeberg's Arch. Pharmacol. 363 (2001) 456
12. Kehrl J.H., Srikumar D., Harrison K., Wilson G., and Shi C.S. Genomics 79 (2002) 860
13. Shi C.S., Lee S.B., Sinnarajah S., Dessauer C.W., Rhee S.G., and Kehrl J.H. J. Biol. Chem. 276 (2001) 24293
14. Rümenapp U., Asmus M., Schablowski H., Wozniki M., Han L., Jakobs K.H., Fahimi-Vahid M., Michalek C., Wieland T., and Schmidt M. J. Biol. Chem. 276 (2001) 2474
15. Jahn L., Sadoshima J., Green A., Parker C., Morgan K.G., and Izumo S. J. Cell Sci. 109 (1996) 397
16. Vögler O., Nolte B., Voss M., Schmidt M., Jakobs K.H., and van Koppen C. J. Biol. Chem. 274 (1999) 12333
17. Lutz S., Freichel-Blomquist A., Rümenapp U., Schmidt M., Jakobs K.H., and Wieland T. Naunyn-Schmiedeberg's Arch. Pharmacol. 369 (2004) 540
18. Benard V., and Bokoch G. Methods Enzymol. 345 (2002) 349
19. Lutz S., Freichel-Blomquist A., Yang Y., Rümenapp U., Jakobs K.H., Schmidt M., and Wieland T. J. Biol. Chem. 280 (2005) 11134
20. Wieland T., Bahtijari N., Zhou X.B., Kleuss C., and Simon M. J. Biol. Chem. 275 (2000) 28500
21. Mao J., Yuan H., Xie W., Simon M., and Wu D. J. Biol. Chem. 273 (1998) 27118
22. Koch W.J., Hawes B.E., Inglese J., Luttrell L.M., and Lefkowitz R.J. J. Biol. Chem. 269 (1994) 6193
23. Nobes C., and Hall A. Biochem. Soc. Trans. 23 (1995) 456
24. Ridley A., Paterson H., Johnston C., Diekmann D., and Hall A. Cell 70 (1992) 401
25. Sander E.E., ten Klooster J.P., van Delft S., van der Kammen R., and Collard J.G. J. Cell Biol. 147 (1999) 1009
26. Nimnual A., Taylor L., and Bar-Sagi D. Nat. Cell Biol. 5 (2003) 236
27. Vogelsgesang M., Pautsch A., and Aktories K. Naunyn-Schmiedeberg's Arch. Pharmacol. (2006) 10.1007/s00210-006-0113-y Online First
28. Cho H., Harrison K., Schwartz O., and Kehrl J.H. Biochem. J. 371 (2003) 973
29. Booden M., Siderovski D., and Der C. Mol. Cell. Biol. 22 (2002) 4053
30. Huang S., Chen L.Y., Zuraw B.L., Ye R.D., and Pan Z.K. J. Biol. Chem. 276 (2001) 40977
31. Togashi H., Emala C., Hall I., and Hirshman C. Am. J. Physiol. 274 (1998) L803
32. Hirshman C., and Emala C. Am. J. Physiol. 27 (1999) L653
33. Burchett S.A., Bannon M.J., and Granneman J.G. J. Neurochem. 72 (1999) 1529
34. House S.L., Bolte C., Zhou M., Doetschman T., Klevitsky R., Newman G., and Jel Schultz J. Circulation 108 (2003) 3140
35. Nishida S., Nagamine H., Tanaka Y., and Watanabe G. Circ. J. 67 (2003)
36. Jin Y., Sheikh F., Detillieux K.A., and Cattini P.A. Mol. Pharmacol. 57 (2000) 984
37. Kim K.S., Takeda K., Sethi R., Pracyk J.B., Tanaka K., Zhou Y.F., Yu Z.X., Ferrans V.J., Bruder J.T., Kovesdi I., Irani K., Goldschmidt-Clermont P., and Finkel T. J. Clin. Invest. 101 (1998) 1821
38. Ozaki M., Haga S., Zhang H.Q., Irani K., and Suzuki S. Cell Death Differ. 10 (2003) 508
39. Yatani A., Irie K., Otani T., Abdellatif M., and Wei L. Am. J. Physiol. 288 (2005) H650
40. Cachero T.G., Morielli A.D., and Peralta E.G. Cell 93 (1998) 1077
41. Sah V.P., Minamisawa S., Tam S.P., Wu T.H., Dorn G.W., Ross Jr. J., Chien K.R., and Brown J.H. J. Clin. Invest. 103 (1999) 1627
42. Wei L., Zhou W., Croissant J.D., Johansen F.E., Prywes R., Balasubramanyam A., and Schwartz R.J. J. Biol. Chem. 273 (1998) 30287
43. Charron F., Tsimiklis G., Arcand M., Robitaille L., Liang Q., Molkentin J.D., Meloche S., and Nemer M. Genes Dev. 15 (2001) 2702