Evidence for a short form of RGS3 preferentially expressed in the human heart

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 363, Issue 4, 2001, Pages 456-463

  Mittmann, C ^a   Schuler C ^a   Chung, C H ^a   Hoppner G ^a   Nose, M ^a   Kehrl, J H ^a   Wieland, T ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

G protein; Human heart; RGS protein

Indexed keywords

ADENYLATE CYCLASE; ENDOTHELIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; PHOSPHOLIPASE C; PROTEIN SUBUNIT; RECOMBINANT PROTEIN; RGS PROTEIN; RGS3 PROTEIN; RIBONUCLEASE; UNCLASSIFIED DRUG;

ALPHA CHAIN; AMINO TERMINAL SEQUENCE; ARTICLE; BRAIN; CONTROLLED STUDY; ENZYME ACTIVITY; HEART; HUMAN; HUMAN TISSUE; LIVER; MYOMETRIUM; NORTHERN BLOTTING; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

BRAIN; GTP-BINDING PROTEINS; GTPASE-ACTIVATING PROTEINS; HUMANS; LIVER; MYOCARDIUM; PROTEIN ISOFORMS; RGS PROTEINS;

EID: 0035087885     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002100000376     Document Type: Article

References (29)

1. Effects of xamoterol on inotropic and lusitropic properties of the human myocardium and on adenylate cyclase activity
2. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
3. Isolation and genetic analysis of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and alpha factor pheromones
4. Physiological characterization of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and alpha factor pheromones
5. A truncated form of RGS3 negatively regulates G protein-coupled receptor stimulation of adenylyl cyclase and phosphoinositide phospholipase C
6. Genomic organization, 5′-flanking region, and chromosomal localization of the human RGS3 gene
7. RGS-r, a retinal specific RGS protein, binds an intermediate conformation of transducin and enhances recycling
8. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
9. GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits
10. Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family
11. Amino-terminal cysteine residues of RGS16 are required for pamitoylation and modulation of Gi- and Gq-mediated signaling
12. RGS3 inhibits G protein-mediated signaling via translocation to the membrane and binding to Galpha11
13. Bovine hereditary cardiomyopathy: An animal model of human dilated cardiomyopathy
14. Apparent up-regulation of stimulatory G-protein alpha subunits in the pregnant human myometrium is mimicked by elevated smoothelin expression
15. Uncoupling of alpha-adrenoceptor-mediated inhibition of human platelet adenylate cyclase by N-ethylmaleimide
16. EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins
17. Guanine nucleotide regulation of a mammalian myocardial muscarinic receptor system. Evidence for homo- and heterotropic cooperativity in ligand binding analyzed by computer-assisted curve fitting
18. Analysis of gene expression patterns in small amounts of human ventricular myocardium by a multiplex RNase protection assay
19. sα the ability interact with regulators of G protein signaling
20. Potential role for a regulator of G protein signaling (RGS3) in gonadotropin-releasing hormone (GnRH) stimulated desensitization
21. Adenylate cyclase assay
22. A role for Rho in receptor- and G protein-stimulated phospho-lipase C. Reduction in phosphatidylinositol 4,5-bisphosphate byClostridium difficile toxin B
23. Plasma membrane localization is required for RGS4 function in Saccharomyces cerevisiae
24. RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits
25. Reduction of myocardial myoglobin in bovine dilated cardiomyopathy
26. Regulators of G-protein signalling: A novel protein family involved in timely deactivation and desensitization of signalling via heterotrimeric G proteins
27. Polarity exchange at the interface of regulators of G protein signaling with G protein α subunits
28. RGS proteins determine signaling specificity of Gq-coupled receptors
29. The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signaling