Understanding childhood depression

Indian Journal of Medical Research

Volumn 125, Issue 2, 2007, Pages 115-128

  Malhotra, Savita ^a   Das, Partha Pratim ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Aetiology; Assessment; Childhood depression; Epidemiology; Genetics; Historical perspective; Management

Indexed keywords

PAROXETINE; PLACEBO; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT;

ACADEMIC ACHIEVEMENT; CHILDHOOD DISEASE; CHRONIC DISEASE; CLINICAL FEATURE; CLINICAL TRIAL; DISEASE SEVERITY; EPIDEMIOLOGICAL DATA; FAMILY STUDY; GENETIC SUSCEPTIBILITY; HISTORY OF MEDICINE; HUMAN; MAJOR DEPRESSION; MOLECULAR GENETICS; NEUROBIOLOGY; PATHOGENESIS; PSYCHOLOGIC ASSESSMENT; PSYCHOLOGICAL ASPECT; REVIEW; RISK FACTOR; SOCIAL PSYCHOLOGY; SUBSTANCE ABUSE; SUICIDAL BEHAVIOR; SUICIDE;

BRAIN; CHILD; DEPRESSIVE DISORDER, MAJOR; GROWTH HORMONE; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; PITUITARY-ADRENAL SYSTEM;

EID: 34147132426     PISSN: 09715916     EISSN: 09715916     Source Type: Journal    
DOI: None     Document Type: Review

References (101)

1. Schulterbrandt JG, Raskin A, editors. Depression in childhood: Diagnosis, treatment and conceptual models. New York: Raven Press; 1977.
2. Hersov L. Emotional disorder. In: Rutter M, Hersov L, editors. Child Psychiatry. London: Blackwell; 1977 p. 444-9.
3. Akiskal HS, Weller ES. Mood disorder and suicide in children and adolescents In: Kaplan HI, Sadock BJ, editors. Comprehensive textbook of psychiatry, Vol. 2, 5th ed. Baltimore: Williams and Wilkins; 1989.
4. Puig- Antich J, Blau S, Marx N, Greenhill L, Chambers W. Pre-pubertal major depressive disorder. Pilot Study. J Am Acad Child Adolescent Psychiatry 1978; 17 : 695-707.
5. Spitz RA, Wolf KM. Anaclitic depression: An enquiry into genesis of psychiatry conditions in early childhood II. Psychoanal Study Child 1946; 2 : 313-42.
6. Glaser K. Masked depression in children and adolescents. Annu Prog Child Psychiatry Child Dev 1968; 1 : 345-55.
7. Frommer EA. Depressive illness in childhood. Br J Psychiatry 1968; 2 : 117-36.
8. Strober M, Green J, Carlson G. Phenomenology and subtypes of major depressive disorder in adolescent. J Affective Disorder 1981; 3 : 281-90.
9. Cytryn L, Mcknew D. Proposed classification of childhood depression. Am J Psychiatry 1972; 129 : 149-55.
10. Weinberg WA, Rutman J, Sullivan L, Penick EC, Dietz SG. Depression in children referred to an educational diagnostic centre: Diagnosis and treatment. J Pediatr 1973; 83 : 1065-72.
11. Feighner JP, Robins E, Guze SB. Diagnostic criteria for use in psychiatric research. Arch Gen Psychiatr 1972; 26 : 57-63.
12. Angold A, Costello EJ. A test re-test reliability of child reported psychiatric symptoms and diagnosis using the child and adolescent psychiatric assessment (CAPA-C). Psychol Med 1995; 25 : 755-62.
13. Coyle JT, Pine DS, Charney DS, Carlson GA, Joshi PT, Reiss D, et al. Depression and bipolar support alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in children and adolescents. J Am Acad Child Adolescent Psychiatry 2003; 42 : 1494-503.
14. Valla J, Bergeron L, Berube H, Gaudet N, St-George M. A structural pictorial questionnaire to asses DSM-III-R- based diagnosis in children (6-11 yrs): development, validity, and reliability. J Abnormal Child Psychol 1994; 22 : 403-23.
15. Ablow JC, Measelle JR, Kraemer HC. The McArthur three city outcome study: evaluating multi-informant measures of young children's symptomatology. J Am Acad Child Adolesc Psychiatr 1999; 38 : 1580-90.
16. Reynolds WM. Assessment of depression in children and adolescents by self report. In: Reynolds W, Johnston H, editors. Handbook of childhood and adolescent depression. New York: Plenum Press; 1994.
17. Poznanski EO, Cook SC, Carroll, BJ, Corzo H. Use of the children's depression rating scale in an inpatient psychiatric population. J Clin Psychiatry 1983; 44 : 200-3.
18. Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23 : 56-62.
19. Kashani JH, Sherman DD. Childhood depression: Epidemiology, etiological models and treatment implications. Integr Psychiatry 1988; 6 : 1-8.
20. Costello EJ, Mustillo S, Erkanli A, Keeler G, Angold A. Prevalence and development of psychiatric disorders in childhood and adolescence. Arch Gen Psychiatry 2003; 60 : 837-44.
21. Choudhury P, Srinath S, Grimaji S, Seshadri S. A study of childhood onset affective disorder. NIMHANS J 1995; 13 : 97-100.
22. Malhotra S, Nitin G, Gagandeep S. Retrospective study of affective disorders in children attending a child psychiatry clinic. Indian J Med Res 1999; 109 : 71-5.
23. Malhotra S, Chakrabarti S. A clinical profile of depression in children. Indian J Social Psychiatry 1992; 8 : 54-8.
24. Malhotra S, Kohli A, Arum P. Prevalence of psychiatric disorders in school children in chandigarh, India. Indian J Med Res 2002; 116 : 21-8.
25. Srinath S, Girimaji SC, Gururaj G, Seshadri S, Subbakrishna DK, Bhola P, et al. Epidemiological study of child and adolescent psychiatric disorders in urban and rural areas of Bangalore, India. Indian J Med Res 2005; 122 : 67-79.
26. Birmaher B, Ryan ND, Williamson DE, Brent DA, Kaufman J, Dahl RE, et al. Childhood and adolescent depression: A review of the past 10 years. Part 1. J Am Acad Child Adolescent Psychiatry 1996; 35 : 1427-39.
27. Carlson GA, Cantwell DP. Unmasking masked depression in children and adolescents. Am J Psychiatry 1980; 137 : 445-9.
28. Petti TA. Depression in hospitalized child psychiatry patients: Approaches to measuring depression. J Am Acad Child Adolescent Psychiatry 1978; 17 : 149-59.
29. Fleming J, Offord DR. Epidemiology of childhood depressive disorders: a critical review. J Am Acad Child Aolescent Psychiatry 1990; 29 : 571-80.
30. Lewinsohn PM, Clarke GN. Major depression in community adolescents: age at onset, episode duration, and time to recurrence. J Am Acad Child Adolescent Psychiatry 1994; 33 : 809-18.
31. Kessler RC, McGonagle KA, Nelson CB, Hughes M, Swartz M, Blazer DG. Sex and depression in the national co morbidity survey: II. Cohort effects. J Affective Disorders l994; 30 : 15-26.
32. Hankin BL, Abramson LY, Moffitt TE, Silva PA, McGee R, Angell KE. Development of depression from preadolescence to young adulthood: Emerging gender differences in a 10-year longitudinal study. J Abnormal Psychology 1998; 107 : 128-40.
33. Costello EJ. Children psychiatric disorders and their correlates: primary care pediatric sample. J Am Acad Child Adolescent Psychiatry 1989; 28 : 851-5.
34. Bird HR, Gould MS, Yager T, Staghezza B, Cannino G. Risk factors for maladjustment in Puerto-Rican children. J Am Acad Child Adolescent Psychiatry 1989; 28 : 847-50.
35. Gilman SE, Kawachi I, Fitzmaurice GM, Buka SL. Socio-economic status, family disruption and residential stability in childhood :relation to onset, recurrence and remission of major depression. Psychol Med 2003; 33 : 1341-55.
36. Biederman J, Faraone S. Psychiatric co-morbidity among referred juveniles with major depression: fact or artifact? J Am Acad Child Adolescent Psychiatry 1995; 34 : 579-90.
37. Kovacs M, Feinberg TL, Crouse-Novak M, Paulauskas SL, Pollock M, Finkelstein R. Depressive disorders in childhood. A longitudinal study of the risk for subsequent major depression. Arch Gen Psychiatry 1984; 41 : 643-9.
38. Kovacs M, Feinberg TL, Crouse-Novak M, Paulauskas SL, Finkelstein R. Depressive disorders in childhood. A Longitudinal study of characteristics and recovery. Arch Gen Psychiatry 1984; 41 : 229-37.
39. Anderson JC, McGee R. Co-morbidity of depression in children and adolescent. In: Reynolds WM, Johnson HF, editors. Handbook of depression in children and adolescents. New York: Plenum; 1994 p. 581-601.
40. Angold A, Costello EJ. Depressive co-morbidity in children and adolescents. Empirical, theoretical, and methodological issues. Am J Psychiatry 1993; 150 : 1779-91.
41. Kovacs M, Goldston D, Gatsonis C. Suicidal behaviors and childhood onset depressive disorder: a longitudinal investigation. J Am Acad Child Adelescent Psychiatry 1993: 32 : 8-20.
42. Harrington R, Fudge H, Rutter M, Pickles A, Hill J. Adult outcomes in child and adolescent depression: I. Psychiatric status. Arch Gen Psychiatry 1990; 47 : 465-73.
43. Harrington R, Fudge H, Rutter M, Pickles A, Hill J. Adult outcome of child and adolescent depression II. Links with antisocial disorders. J Am Acad Child Adolescent Psychiatry 1991; 30 : 434-9.
44. Puig- Antich J, Goetz R. A controlled family history of study of pre-pubetral major depressive disorder. Arch Gen Psychiatry 1989; 46 : 406-18.
45. Hughes C, Preskorn S, Weller E, Weller R, Hassanein R, Tucker S. The effects of concomitant disorders in childhood depression on predicting treatment response. Psychopharmacol Bull 1990; 26 : 235-8.
46. Lewinsohn PM, Duncan EM. Age at onset of first unipolar depression. J Abnorm Psychol 1986; 95 : 378-83.
47. Burke MJ, Preskorn SH. Short term treatment of mood disorders with standard antidepressant. In: Bloom FE, Kupfer DJ, editors. Psychopharmacology: The fourth generation of progress. New York: Raven Press; 1995 p. 1053-106.
48. Williamson DE, Ryan ND, Birmaher B, Dahl RE, Nelson B. A case control family history study of depression in adolescents. J Am Child Adolescent Psychiatry 1995; 34 : 1596-607.
49. Kovacs M, Gatsonis C. Secular trends in age at onset of major depressive disorder in a clinical sample of children. J Psychiatr Res 1994; 28 : 319-29.
50. Ryan ND, Williamson DE, Iyengar S. A secular increase in child and adolescent onset affective disorder. J Am Acad Child Adolesc Psychiatry 1992; 31 : 600-5.
51. McCauley E, Myers K, Mitchel J, Caldron R, Schloredt K, Treder R. Depression in young people. Initial presentation and clinical course. J Am Acad Child Adolescent Psychiatry 1993; 32 : 714-22.
52. Lewinsohn PM, Rohde P, Klein DN, Seeley JR. Natural course of adolescent major depressive disorder: I. Continuity into young adulthood. J Am Acad Child Adolescent Psychiatry 1999; 38 : 56-63.
53. Fleming J, Offord DR. The outcome of adolescent depression in the Ontario Child Health Study follow up. J Am Acad Child Adolescent Psychiatry 1993; 32 : 28-33.
54. Strober M, Lampert C, Schmidt M, Morrel W.The course of major depressive disorder in adolescents: I. Recovery and risk of manic switch in a follow up of psychotic and nonpsychotic subtypes. J Am Acad Child Adolescent Psychiatry 1993; 32 : 34-42.
55. Coryell W, Keller M, Endicott J, Andreason N, Clayton P, Hirschfeld R. Bipolar II illness: course and outcome over a five year period. Psychol Med 1989; 19 : 129-41.
56. Rao U, Ryan ND, Birmaher B. Unipolar depression in adolescents; clinical outcome in adulthood. J Am Acad Child Adolescent Psychiatry 1995; 34 : 566-78.
57. Akiskal HS, Maser JD, Zeller PJ. Switching from unipolar to bipolar II: an 11-yr prospective study of clinical and temperamental predictors in 559 patients. Arch Gen Psychiatry 1995; 52 : 114-23.
58. Shaffer D. Depressive disorder and suicide in children and adolescents. In: Sadock BJ, Sadock VA, editors. Comprehensive textbook of psychiatry, vol2, 8th ed. Lippincott: Williams and Wilkins; 2005 p. 3262-73.
59. Carlson GA, Kashani JH. Phenomenology of major depression from childhood through adulthood: analysis of three studies. Am J Psychiatry 1988; 145 : 1222-5.
60. Asarnow JR, Ben-Meir S. Children and schizophrenia spectrum and depressive disorders: a comparative study of pre-morbid adjustment, onset pattern and severity of impairment. J Child Psychol Psychiatry 1988; 29 : 477-88.
61. Asarnow JR, Tompson M, Hamilton EB, Goldstein MJ, Guthrie D. Family expressed emotion, childhood onset depression, childhood onset schizophrenia spectrum disorders: is expressed emotion a non specific correlate of childhood psychopathology or a specific risk factor for depression. J Abnormal Child Psychol 1994; 22 : 129-46.
62. Nolen-Hoeksema S, Girgus JS, Seligman MEP. Predictors and consequences of childhood depressive symptoms: a 5-yr longitudinal study. J Abnormal Psychol 1992; 101 : 405-22.
63. Orvaschel H, Walsh-Allis G, Ye W. Psychopathology in children of parents with recurrent depression. J Abnormal Child Psychol 1988; 16 : 17-28.
64. Hammen C, Barge D, Burney E, Adrian C. Longitudinal study of diagnosis in children of women with unipolar depression and bipolar affective disorder. Arch Gen Psychiatry 1990; 47 : 1112-7.
65. Merikangas KR, Weissman MM, Prusoff BA, John K. Assortative mating and affective disorders: Psychopathology in offspring. Psychiatry 1988; 51 : 48-57.
66. Weissman MM, Warner V, Wickramaratne P, Prusoff BA. Early onset depression in parents and their children. J Affective Disorder 1988; 15 : 269-77.
67. Duman R S, The neurochemistry of mood disorders: Preclinical studies In: Charney DS, Nestler EJ, Bunney BS, editors. Neurobiology of mental illness. New York: Oxford University Press; 1999 p. 333-47.
68. Nobile M, Giulia Cataldo M, Giorda R, Battaglia M, Baschirotto C, Bellina M. A case-control and family-based association study of the 5-HTTLPR in pediatric-onset depressive disorders. Biological Psychiatry 2004; 56 : 292-5.
69. McCauley E, Myers K. Family interactions in mood disordered youth. Child Adolescent Psychiatr Clin North America 1992; 1 : 111-27.
70. Beardslee WR, Versage EM, Gladstone TR. Children of affectively ill parents: A review of the past 10 years. J Am Acad Child Adolescent Psychiatry 1998; 37 : 1134-41.
71. Klein D, Lewinsohn PM, Rohde P, Seeley JR, Olino TM. Psychopathology in the adolescent and young adult offspring of a community sample of mothers and fathers with major depression. Psychol Med 2005; 35 : 353-65.
72. Williamson DE, Ryan ND, Dahl RE, Brook JL. Stressful life events in depressed adolescents: the role of dependent events during the depressive episode. J Am Acad Child Adolescent Psychiatry 1995; 34 : 591-8.
73. Briere J. Child Abuse Trauma: Theory and Treatment of the Lasting Effects. Newbury Park, CA: Sage Publication; 1992.
74. Caspi A, Henry B, McGee R O, Moffitt T E, Silva P A. Temperamental origins of child and adolescent behavior problems: from age three to age fifteen. Child Dev 1995; 66 : 55-68.
75. Kagan J. Emotional development and Psychiatry. Biol Psychiatry 2001; 49 : 973-9.
76. Merikangas KR, Swendsen JD, Preisig MA, Chazan RZ. Psychopathology and temperament in parents and offspring.: results of a family study. J Affective Disorder 1998; 51 : 63-74.
77. Elovainio M, Kivimaki M, Puttonen S, Heponiemi T, Pulkki L, Keltikangas-Jarvinen L. Temperament and depressive symptoms: a population based longitudinal study on Cloninger's psychobiological temperamental model. J Affective Disorder 2004; 83 : 227-34.
78. Steingard RJ, Renshaw PF, Deborah YT, Appelmans KE, Lyoo IK, Shorrock KL, et al. Structural abnormalities in brain magnetic resonance images of depressed children. Am Acad Child Adolescent Psychiatry 1996; 35 : 307-11.
79. Nolan CL, Moore GJ, Madden R, Farchione T, Bartoi M, Lorch E, et al. Pre-frontal cortical volume in childhood-onset depression. Arch Gen Psychiatry 2002; 59 : 173-9.
80. Botterton KN, Raichle ME, Drevets WC, Health AC, Todd RD. Volumetric reduction in left sub-genual prefrontal cortex in early onset depression. Biol Psychiatry 2002; 51 : 342-4.
81. Steffens DC, Krishnan KR. Structural neuroimaging and mood disorder: recent findings, implication for classification, and future directions. Biol Psychiatry 1998; 43 : 705-12.
82. Erhlich S, Noam GG, Lyoo IK, Kwon B J, Clark MA, Renshaw PF. White matter hyper-intensities and their association with suicidality in psychiatrically hospitalized children and adolescents. J Am Acad Child Adolescent Psychiatry 2004; 43 : 770-6.
83. Thomas KM, Wayne CD, Dahl RE, Ryan ND, Birmaher B, Eccard CH, et al. Amygdala responses to fearful faces in anxious and depressed children. Arch Gen Psychiatry 2001; 58 : 1057-63.
84. MacMillan S, Szeszko PR, Moore GJ, Madden R, Lorch E, Ivey J, et al. Increased amygdala: Hippocampal volume ratios associated with severity of anxiety in pediatric major depression. J Child Adolescent Psychopharmacol 2003; 13 : 65-73.
85. MacMaster FP, Kusumakar V. Hippocampal volume in early onset depression. BMC Med 2004; 2 : 2-8.
86. Rosso IM, Cintron CM, Steingard RJ, Renshaw PF, Young AD, Deborah A, et al. Amygdala and hippocampal volumes in pediatric major depression. Biol Psychiatry2005; 57 : 21-6.
87. Bonte FJ, Trivedi MH, Devous MD, Harris TS, Payne K, Weinberg WA, et al. Occipital brain perfusion deficits in children with major depressive disorder. J Nucl Med 2001; 42 : 1059-61.
88. Farchione TR, Moore GJ, Rosenberg DR. Proton magnetic resonance spectroscopic imaging in pediatric major depression. Biol Psychiatry 2002; 52 : 66-92.
89. Steingard RJ, Yurgelum-Todd DA, Hennen J, Moore JC, Moore CM, Vakli K, et al. Increased orbito-frontal cortex levels of choline in depressed adolescents as detected by in vivo proton magnetic resonance spectroscopy. Biol Psychiatry 2000; 48 : 1053-61.
90. Pfeiderer B, Michael N, Erfurth A, Ohrmann P, Hohmann U, Wolgast M, et al. Effective electro convulsive therapy reverses glutamate/glutamine deficit in the left anterior cingulum of unipolar depressed patients. Psychiatry Res 2003; 122 : 185-92.
91. Theberge J, Bartha R, Drost DJ. Glutamate and glutamine measured with 4.0 T proton MRS in never treated patients with schizophrenia and healthy volunteers. Am J Psychiatry 2002; 159 : 1944-6.
92. Castillo M, Kwock L, Courvoisie H, Hopper S R. Proton M R spectroscopy in children with bipolar affective disorder: preliminary observations. Am J Neuroradiol 2000; 21 : 832-8.
93. Mirza Y, Jennifer T, Russell A, Banerjee P, Bhandari R, Ivey J, et al. Reduced anterior cingulated cortex glutaminergic concentrations in childhood major depression. J Am Acad Child Adolescent Psychiatry 2004; 43 : 341-8.
94. Kaufman J, Martin A, King RA, Charney D. Are childadolescent and adult-onset depression one and the same disorder? Biol Psychiatry 2001; 49 : 980-1001.
95. Casat CD, Arana GL. The DST in children and adolescent with major depression. Am J Psychiatry 1989; 146 : 503-7.
96. Ryan ND, Dahl RE, Birmaher B. Stimulatory tests of growth hormone secretion in pre-pubetral depression: Depression versus normal children. J Am Acad Child Adolescent Psychiatry 1994; 33 : 854-61.
97. Birmaher B, Brent D A, Benson R S. Summary of the practice parameters for assessment and treatment of children and adolescents with depressive disorders. J Am Acad Child Adolescent Psychiatry 1998; 37 : 1234-8.
98. Reinecke MA, Ryan NE, DuBois DL. Cognitive-behavioral therapy of depression and depressive symptoms during adolescence: a review and meta-analysis. J Am Acad Child Adolesc Psychiatry 1998; 37: 26-34.
99. Daly JM, Wilens T. The use of tricyclic antidepressants in children and adolescents. Pediatr Clin North Am 1998; 45 : 1123-35.
100. Cheung AH, Emslie GJ, Mayes TL. Review of the efficacy and safety of antidepressants in youth depression. J Child Psychol Psychiatry 2005; 46 : 735-54.
101. Tonkin A, Jureidine J. Wishful thinking: antidepressant drugs in childhood depression. Br J Psychiatry 2005; 187 : 304-5.