Inhibition of calcineurin and sarcolemmal Ca2+ influx protects cardiac morphology and ventricular function in Kv4.2N transgenic mice

Circulation

Volumn 105, Issue 15, 2002, Pages 1850-1856

  Sah, Rajan ^a   Oudit, Gavin Y ^a   Nguyen, The Tin T ^a   Lim, Hae W ^a   Wickenden, Alan D ^a   Wilson, Gregory J ^a   Molkentin, Jeffery D ^a   Backx, Peter H ^a  

^a HEART AND STROKE FOUNDATION OF CANADA   (Canada)

Author keywords

Action potentials; Cardiomyopathy; Contractility; Ion channels

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCINEURIN; CALCIUM ION; CYCLOSPORIN A; MYOSIN HEAVY CHAIN; MYOSIN HEAVY CHAIN BETA; PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C THETA; PROTEIN SERCA2A; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; HEART DISEASE; HEART MUSCLE FIBROSIS; HEART VENTRICLE CONTRACTILITY; HEART VENTRICLE FUNCTION; MALE; MORPHOLOGY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SARCOLEMMA; TRANSGENIC MOUSE;

ACTION POTENTIALS; ANIMALS; BIOLOGICAL TRANSPORT; CALCINEURIN; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM-TRANSPORTING ATPASES; CARDIAC MYOSINS; CELLS, CULTURED; HEART; HEART DISEASES; KINETICS; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCARDIUM; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN KINASE C; SARCOLEMMA; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SHAL POTASSIUM CHANNELS; VENTRICULAR FUNCTION; VERAPAMIL;

EID: 0037117662     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000014211.47830.4D     Document Type: Article

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