Direct intermolecular hydroacylation of N,N-dialkylacrylamides with aldehydes catalyzed by a cationic rhodium(I)/dppb complex

Organic Letters

Volumn 9, Issue 7, 2007, Pages 1215-1218

  Tanaka, Ken ^a   Shibata, Yu ^a   Suda, Takeshi ^a   Hagiwara, Yuji ^a   Hirano, Masao ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 34147095358     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol070153s     Document Type: Article

References (53)

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51. 1H NMR analysis of the crude reaction mixture.
52. 1H NMR analysis of the crude reaction mixture.
53. Treatment of aldehyde 1a or 1d and N,N- dimethylmethacrylamide (2c) with dppb (5 mol %) at 80 °C for 5 h furnished no hydroacylation product. This result denies the possibility of a dppb-catalyzed Stetter reaction. For tributylphosphine-mediated Stetter reaction of arylaldehydes and N,N-dialkylacrylamides, see: Gong, J. H.; Im, Y. J.; Lee, K. Y.; Kim, J. N. Tetrahedron Lett. 2002, 43, 1247.