Chelation-Assisted Intermolecular Hydroacylation: Direct Synthesis of Ketone from Aldehyde and 1-Alkene

Journal of Organic Chemistry

Volumn 62, Issue 5, 1997, Pages 1200-1201

  Jun, Chul Ho ^a   Lee, Hyuk ^a   Hong, Jun Bae ^a  

^a Yonsei University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000685510     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo961887d     Document Type: Article

References (28)

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25. 2) to give 60.1 mg of 5a (72% isolated yield), which was characterized by spectroscopic analysis.
26. 5 300.057356, found 300.057686.
27. Intermediates, aldimine 6 (R = Ph), and complex 7 were already Prepared and characterized in ref 7a.
28. Other 2-aminopyridine derivatives have been tested for this reaction, and 2-amino-3-picoline showed the best result. Toluene and THF did not show any large difference in results, but we preferred THF to toluene under mild conditions such as 100°C.