Liquid chromatography tandem mass spectrometry assay to determine the pharmacokinetics of aildenafil in human plasma

Journal of Pharmaceutical and Biomedical Analysis

Volumn 44, Issue 1, 2007, Pages 231-235

  Wang, Jiang ^a   Jiang, Yao ^a   Wang, Yingwu ^a   Zhao, Xia ^b   Cui, Yimin ^b   Gu, Jingkai ^a  

^a JILIN UNIVERSITY   (China)

^b PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

Aildenafil; LC MS MS; Pharmacokinetics

Indexed keywords

ACETIC ACID; AILDENAFIL; AMMONIA; BUFFER; METHANOL; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; UNCLASSIFIED DRUG;

ACCURACY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; NORMAL HUMAN; PRIORITY JOURNAL; STANDARDIZATION; SUSTAINED RELEASE PREPARATION; TANDEM MASS SPECTROMETRY;

ACETATES; ADMINISTRATION, ORAL; AMMONIA; AREA UNDER CURVE; BUFFERS; CALIBRATION; CHROMATOGRAPHY, LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; FASTING; HALF-LIFE; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; METABOLIC CLEARANCE RATE; METHANOL; MOLECULAR STRUCTURE; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; PURINES; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SULFONES; TABLETS; TANDEM MASS SPECTROMETRY; TIME FACTORS;

EID: 34047244925     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2007.01.017     Document Type: Article

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