"Plate cherry picking": A novel semi-sequential screening paradigm for cheaper, faster, information-rich compound selection

Journal of Biomolecular Screening

Volumn 12, Issue 3, 2007, Pages 320-327

  Crisman, Thomas J ^a   Jenkins, Jeremy L ^a   Parker, Christian N ^b   Hill, W Adam G ^a   Bender, Andreas ^a   Deng, Zhan ^a   Nettles, James H ^a   Davies, John W ^a   Glick, Meir ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Cherry picking; High throughput screening; Plate diversity approach; Semi sequential screening

Indexed keywords

CHEMOKINE RECEPTOR; G PROTEIN COUPLED RECEPTOR; METALLOPROTEINASE; PROTEIN KINASE; REAGENT;

ARTICLE; BIOASSAY; CELL COUNT; COST EFFECTIVENESS ANALYSIS; DRUG DESIGN; DRUG INDUSTRY; HIGH THROUGHPUT SCREENING; IC 50; INTERMETHOD COMPARISON; PLATE CHERRY PICKING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RETROSPECTIVE STUDY; SIGNAL TRANSDUCTION; SIMULATION; STATISTICAL MODEL;

BAYES THEOREM; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG EVALUATION, PRECLINICAL; PHARMACEUTICAL PREPARATIONS; SOFTWARE; TIME FACTORS;

EID: 34047174584     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057107299427     Document Type: Article

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