Altitude-related cough

Pulmonary Pharmacology and Therapeutics

Volumn 20, Issue 4, 2007, Pages 388-395

  Mason, Nicholas P ^a   Barry, Peter W ^b  

^a UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^b LEICESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Cough; Environment; High altitude; Hypobaric hypoxia

Indexed keywords

ANTIHISTAMINIC AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CODEINE PHOSPHATE; CORTICOSTEROID;

ALTITUDE; ALTITUDE DISEASE; ARTICLE; BRONCHOSPASM; COUGHING; EXERCISE; HUMAN; HYPOXIA; LUNG EDEMA; PRIORITY JOURNAL; RESPIRATION CONTROL; RESPIRATORY TRACT INFECTION; VASOMOTOR RHINITIS; WATER LOSS;

ACUTE DISEASE; ALTITUDE; ALTITUDE SICKNESS; COUGH; HUMANS; MOUNTAINEERING; RESPIRATION; RESPIRATORY TRACT DISEASES; WATER LOSS, INSENSIBLE;

EID: 34047125998     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2006.10.018     Document Type: Article

References (89)

1. Tasker J. Everest the cruel way (1981), Eyre Methuen, London
2. Somervell T. After Everest (1936), Hodder and Stoughton, London
3. Steele P. Medicine on Mount Everest 1971. Lancet 2 (1971) 32-39
4. Litch J.A., and Tuggy M. Cough induced stress fracture and arthropathy of the ribs at extreme altitude. Int J Sports Med 19 (1998) 220-222
5. Murdoch D.R. Symptoms of infection and altitude illness among hikers in the Mount Everest region of Nepal. Aviat Space Environ Med 66 (1995) 148-151
6. Barry P.W., Mason N.P., Riordan M., and O'Callaghan C. Cough frequency and cough-receptor sensitivity are increased in man at altitude. Clin Sci (Colch) 93 (1997) 181-186
7. Houston C.S., Sutton J.R., Cymerman A., and Reeves J.T. Operation Everest II: man at extreme altitude. J Appl Physiol 63 (1987) 877-882
8. Mason N.P., Barry P.W., Despiau G., Gardette B., and Richalet J.P. Cough frequency and cough receptor sensitivity to citric acid challenge during a simulated ascent to extreme altitude. Eur Respir J 13 (1999) 508-513
9. Banner A., and Green J. Effects of hypernea with cold air in subjects with exercise-induced cough. Am. Rev. Respir. Dis. 129 (1984) 261
10. Banner A.S., Green J., and O'Connor M. Relation of respiratory water loss to coughing after exercise. N Engl J Med 311 (1984) 883-886
11. Mason N.P. The physiology of high altitude: an introduction to the cardiorespiratory changes occurring on ascent to altitude. Curr Anaesth Crit Care 11 (2000) 34-41
12. Pugh L., Gill M., Lahiri S., Milledge J., Ward M., and West J. Muscular exercise at great altitude. J Appl Physiol 19 (1964) 431-440
13. Widdicombe J.G. Nasal airflow resistance at simulated altitude. Eur Respir J 19 (2002) 4-5
14. Barry P.W., Mason N.P., and O'Callaghan C. Nasal mucociliary transport is impaired at altitude. Eur Respir J 10 (1997) 35-37
15. Barry P.W., Mason N.P., and Richalet J.P. Nasal peak inspiratory flow at altitude. Eur Respir J 19 (2002) 16-19
16. Svensson S., Olin A.C., and Hellgren J. Increased net water loss by oral compared to nasal expiration in healthy subjects. Rhinology 44 (2006) 74-77
17. Bartsch P., Mairbaurl H., Maggiorini M., and Swenson E.R. Physiological aspects of high-altitude pulmonary edema. J Appl Physiol 98 (2005) 1101-1110
18. Mason N. The pathology of high altitude: an introduction to the disease states of high altitude. Curr Anaesth Crit Care 11 (2000) 104-112
19. Hultgren H.N., Lopez C.E., Lundberg E., and Miller H. Physiologic studies of pulmonary edema at high altitude. Circulation 29 (1964) 393-408
20. Mason N.P., Barry P.W., Pollard A.J., Collier D.J., Taub N.A., Miller M.R., et al. Serial changes in spirometry during an ascent to 5300 m in the Nepalese Himalayas. High Alt Med Biol 1 (2000) 185-195
21. Gray G., McFadden D., Houston C., and Bryan A. Changes in the single-breath nitrogen washout curve on exposure to 17,600 ft. J Appl Physiol 39 (1975) 652-656
22. Coates G., Gray C., Mansell A., Nahmias C., Powles A., Sutton J., et al. Changes in lung volume, lung density, and distribution of ventilation during hypobaric decompression. J Appl Physiol 46 (1979) 752-755
23. Cremona G., Asnaghi R., Baderna P., Brunetto A., Brutsaert T., Cavallaro C., et al. Pulmonary extravascular fluid accumulation in recreational climbers: a prospective study. Lancet 359 (2002) 303-309
24. Welsh C.H., Wagner P.D., Reeves J.T., Lynch D., Cink T.M., Armstrong J., et al. Operation Everest. II: Spirometric and radiographic changes in acclimatized humans at simulated high altitudes. Am Rev Respir Dis 147 (1993) 1239-1244
25. Mason N.P., Petersen M., Melot C., Imanow B., Matveykine O., Gautier M.T., et al. Serial changes in nasal potential difference and lung electrical impedance tomography at high altitude. J Appl Physiol 94 (2003) 2043-2050
26. Nieminen M.S., Bohm M., Cowie M.R., Drexler H., Filippatos G.S., Jondeau G., et al. Executive summary of the guidelines on the diagnosis and treatment of acute heart failure: the Task Force on Acute Heart Failure of the European Society of Cardiology. Eur Heart J 26 (2005) 384-416
27. Paintal A.S. Mechanism of stimulation of type J pulmonary receptors. J Physiol 203 (1969) 511-532
28. Roberts A.M., Bhattacharya J., Schultz H.D., Coleridge H.M., and Coleridge J.C. Stimulation of pulmonary vagal afferent C-fibers by lung edema in dogs. Circ Res 58 (1986) 512-522
29. Widdicombe J.G. Neurophysiology of the cough reflex. Eur Respir J 8 (1995) 1193-1202
30. Widdicombe J.G. Afferent receptors in the airways and cough. Respir Physiol 114 (1998) 5-15
31. Mazzone S.B. An overview of the sensory receptors regulating cough. Cough 1 (2005) 2
32. Staub N.C., Nagano H., and Pearce M.L. Pulmonary edema in dogs, especially the sequence of fluid accumulation in lungs. J Appl Physiol 22 (1967) 227-240
33. Bonham A.C., Kott K.S., Ravi K., Kappagoda C.T., and Joad J.P. Substance P contributes to rapidly adapting receptor responses to pulmonary venous congestion in rabbits. J Physiol 493 (1996) 229-238
34. Gunawardena S., Bravo E., and Kappagoda C.T. Effect of chronic mitral valve damage on activity of pulmonary rapidly adapting receptors in the rabbit. J Physiol 511 (1998) 79-88
35. Gunawardena S., Bravo E., and Kappagoda C.T. Rapidly adapting receptors in a rabbit model of mitral regurgitation. J Physiol 521 Pt 3 (1999) 739-748
36. Hargreaves M., Ravi K., and Kappagoda C.T. Responses of slowly and rapidly adapting receptors in the airways of rabbits to changes in the Starling forces. J Physiol 432 (1991) 81-97
37. Bartsch P., Maggiorini M., Ritter M., Noti C., Vock P., and Oelz O. Prevention of high-altitude pulmonary edema by nifedipine. N Engl J Med 325 (1991) 1284-1289
38. Scherrer U., Vollenweider L., Delabays A., Savcic M., Eichenberger U., Kleger G.R., et al. Inhaled nitric oxide for high-altitude pulmonary edema. N Engl J Med 334 (1996) 624-629
39. Matalon S., and O'Brodovich H. Sodium channels in alveolar epithelial cells: molecular characterization, biophysical properties, and physiological significance. Annu Rev Physiol 61 (1999) 627-661
40. Matthay M.A., Folkesson H.G., and Clerici C. Lung epithelial fluid transport and the resolution of pulmonary edema. Physiol Rev 82 (2002) 569-600
41. Matthay M.A., and Wiener-Kronish J.P. Intact epithelial barrier function is critical for the resolution of alveolar edema in humans. Am Rev Respir Dis 142 (1990) 1250-1257
42. Planes C., Escoubet B., Blot-Chabaud M., Friedlander G., Farman N., and Clerici C. Hypoxia downregulates expression and activity of epithelial sodium channels in rat alveolar epithelial cells. Am J Respir Cell Mol Biol 17 (1997) 508-518
43. Planes C., Friedlander G., Loiseau A., Amiel C., and Clerici C. Inhibition of Na-K-ATPase activity after prolonged hypoxia in an alveolar epithelial cell line. Am J Physiol 271 (1996) L70-L78
44. Planes C., Blot-Chabaud M., Matthay M.A., Couette S., Uchida T., and Clerici C. Hypoxia and beta 2-agonists regulate cell surface expression of the epithelial sodium channel in native alveolar epithelial cells. J Biol Chem 277 (2002) 47318-47324
45. Mairbaurl H., Wodopia R., Eckes S., Schulz S., and Bartsch P. Impairment of cation transport in A549 cells and rat alveolar epithelial cells by hypoxia. Am J Physiol 273 (1997) L797-L806
46. Vivona M.L., Matthay M., Chabaud M.B., Friedlander G., and Clerici C. Hypoxia reduces alveolar epithelial sodium and fluid transport in rats: reversal by beta-adrenergic agonist treatment. Am J Respir Cell Mol Biol 25 (2001) 554-561
47. Mairbaurl H., Weymann J., Mohrlein A., Swenson E.R., Maggiorini M., Gibbs J.S., et al. Nasal epithelium potential difference at high altitude (4559 m): evidence for secretion. Am J Respir Crit Care Med 167 (2003) 862-867
48. Sartori C., Duplain H., Lepori M., Egli M., Maggiorini M., Nicod P., et al. High altitude impairs nasal transepithelial sodium transport in HAPE-prone subjects. Eur Respir J 23 (2004) 916-920
49. Sartori C., Allemann Y., Duplain H., Lepori M., Egli M., Lipp E., et al. Salmeterol for the prevention of high-altitude pulmonary edema. N Engl J Med 346 (2002) 1631-1636
50. Bakewell S.E., Hart N.D., Wilson C.M., McMorrow R., Collier D., Williams D., et al. A randomised, double blind, placebo controlled trial of the effect of inhaled nedocromil sodium or salmeterol xinafoate on the citric acid cough threshold in subjects travelling to high altitude (abstract). In: Roach R.C., Wagner P.D., and Hackett P.H. (Eds). Hypoxia: into the next millennium (1999), Plenum/Kluwer Academic Publishing, New York 362
51. Mairbaurl H., Schwobel F., Hoschele S., Maggiorini M., Gibbs S., Swenson E.R., et al. Altered ion transporter expression in bronchial epithelium in mountaineers with high-altitude pulmonary edema. J Appl Physiol 95 (2003) 1843-1850
52. Maggiorini M., Buhler B., Walter M., and Oelz O. Prevalence of acute mountain sickness in the Swiss Alps. BMJ 301 (1990) 853-855
53. Ward M., Milledge J.S., and West J.B. Acute mountain sickness. High altitude medicine and physiology. 3rd ed (2000), Arnold, London 215-231
54. Roach R., Bartsch P., Hackett P., and Oelz O. The Lake Louise acute mountain sickness scoring system. In: Sutton J., Houston C., and Coates G. (Eds). Hypoxia and Mountain medicine (1993), Queen City Printers, Burlington 327-330
55. Dicpinigaitis P.V. Cough 4: cough in asthma and eosinophilic bronchitis. Thorax 59 (2004) 71-72
56. Dicpinigaitis P.V. Chronic cough due to asthma: ACCP evidence-based clinical practice guidelines. Chest 129 (2006) 75S-79S
57. Strauss R.H., McFadden Jr. E.R., Ingram Jr. R.H., and Jaeger J.J. Enhancement of exercise-induced asthma by cold air. N Engl J Med 297 (1977) 743-747
58. Deal Jr. E.C., McFadden Jr. E.R., Ingram Jr. R.H., Breslin F.J., and Jaeger J.J. Airway responsiveness to cold air and hyperpnea in normal subjects and in those with hay fever and asthma. Am Rev Respir Dis 121 (1980) 621-628
59. Parsons J.P., and Mastronarde J.G. Exercise-induced bronchoconstriction in athletes. Chest 128 (2005) 3966-3974
60. Gotshall R.W. Exercise-induced bronchoconstriction. Drugs 62 (2002) 1725-1739
61. Strauss R.H., McFadden Jr. E.R., Ingram Jr. R.H., Deal Jr. E.C., and Jaeger J.J. Influence of heat and humidity on the airway obstruction induced by exercise in asthma. J Clin Invest 61 (1978) 433-440
62. Belcher N., and Rees P.J. Effects of pholcodine and salbutamol on citric acid induced cough in normal subjects. Thorax 41 (1986) 74-75
63. Nadel J.A., and Widdicombe J.G. Effect of changes in blood gas tensions and carotid sinus pressure on tracheal volume and total lung resistance to airflow. J Physiol 163 (1962) 13-33
64. Green M., and Widdicombe J.G. The effects of ventilation of dogs with different gas mixtures on airway calibre and lung mechanics. J Physiol 186 (1966) 363-381
65. Reynolds A.M., and McEvoy R.D. Tachykinins mediate hypocapnia-induced bronchoconstriction in guinea pigs. J Appl Physiol 67 (1989) 2454-2460
66. Pollard A.J., Barry P.W., Mason N.P., Collier D.J., Pollard R.C., Pollard P.F., et al. Hypoxia, hypocapnia and spirometry at altitude [published erratum appears in Clin Sci (Colch) 1997 Dec;93(6):611]. Clin Sci (Colch) 92 (1997) 593-598
67. Pratter M.R. Cough and the common cold: ACCP evidence-based clinical practice guidelines. Chest 129 (2006) 72S-74S
68. Irwin R.S., Rosen M.J., and Braman S.S. Cough. A comprehensive review. Arch Intern Med 137 (1977) 1186-1191
69. Basnyat B., and Litch J.A. Medical problems of porters and trekkers in the Nepal Himalaya. Wilderness Environ Med 8 (1997) 78-81
70. Rabold M. High altitude bronchitis on Cerro Aconcagua (abstract). Wilderness Medical Society Newsletter, 1987.
71. Richalet J.P., Robach P., Jarrot S., Schneider J.C., Mason N.P., Cauchy E., et al. Operation Everest III (COMEX '97). Effects of prolonged and progressive hypoxia on humans during a simulated ascent to 8848 M in a hypobaric chamber. Adv Exp Med Biol 474 (1999) 297-317
72. Hallander H.O., Gnarpe J., Gnarpe H., and Olin P. Bordetella pertussis, Bordetella parapertussis, Mycoplasma pneumoniae, Chlamydia pneumoniae and persistent cough in children. Scand J Infect Dis 31 (1999) 281-286
73. Birkebaek N.H., Kristiansen M., Seefeldt T., Degn J., Moller A., Heron I., et al. Bordetella pertussis and chronic cough in adults. Clin Infect Dis 29 (1999) 1239-1242
74. Jacoby D.B. Pathophysiology of airway viral infections. Pulm Pharmacol Ther 17 (2004) 333-336
75. Pratter M.R. Chronic upper airway cough syndrome secondary to rhinosinus diseases (previously referred to as postnasal drip syndrome): ACCP evidence-based clinical practice guidelines. Chest 129 (2006) 63S-71S
76. Morice A.H., and Kastelik J.A. Cough 1: chronic cough in adults. Thorax 58 (2003) 901-907
77. Ward M., Milledge J.S., and West J.B. Ventilatory response to hypoxia and carbon dioxide. High altitude medicine and physiology. 3rd ed (2000), Arnold, London 50-64
78. Bonham A.C., Sekizawa S.I., Chen C.Y., and Joad J.P. Plasticity of brainstem mechanisms of cough. Respir Physiol Neurobiol (2006)
79. Bonham A.C., Chen C.Y., Sekizawa S., and Joad J.P. Plasticity in the nucleus tractus solitarius and its influence on lung and airway reflexes. J Appl Physiol 101 (2006) 322-327
80. Bolser D.C., and Davenport P.W. Functional organization of the central cough generation mechanism. Pulm Pharmacol Ther 15 (2002) 221-225
81. Gothe B., Altose M.D., Goldman M.D., and Cherniack N.S. Effect of quiet sleep on resting and CO2-stimulated breathing in humans. J Appl Physiol 50 (1981) 724-730
82. Douglas N.J. Control of breathing during sleep. Clin Sci (London) 67 (1984) 465-471
83. Gutstein H., and Akil H. Opioid analgesics-centrally acting anti-tussive agents. In: Brunton L. (Ed). Goodman and Gilman's The pharmacological basis of therapeutics. 11th ed (2006), McGraw-Hill, New York 578-579
84. Banner A.S. Relationship between cough due to hypotonic aerosol and the ventilatory response to CO2 in normal subjects. Am Rev Respir Dis 137 (1988) 647-650
85. Barry P., Mason N., Nickol A., Datta A., Milledge J., Wolffe C., et al. Cough receptor sensitivity and dynamic ventilatory response to carbon dioxide in man acclimatised to high altitude (Abstract). J. Physiol. 497 (1996) 29-30
86. Svartengren M., Anderson M., Philipson K., and Camner P. Human lung deposition of particles suspended in air or in helium/oxygen mixture. Exp Lung Res 15 (1989) 575-585
87. Lumb A. Respiratory system resistance. Nunn's applied respiratory physiology (2000), Butterworth-Heinemann, Edinburgh 58-81
88. Barry P. The output of nebulisers at high altitude (abstract). High Alt Med Biol 2 (2000) 114
89. Barry P., Hart N., Wilson C., Bakewell S., McMorrow R., Watt S., et al. Lung deposition of therapeutic aerosols at simulated altitude (abstract). High Alt Med Biol 2 (2000) 114