Substance P contributes to rapidly adapting receptor responses to pulmonary venous congestion in rabbits

Journal of Physiology

Volumn 493, Issue 1, 1996, Pages 229-238

  Bonham, A C ^a   Kott, K S ^a   Ravi, K ^a   Kappagoda, C T ^a   Joad, J P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 BENZHYDRYL 3 (2 METHOXYBENZYLAMINO) 1 AZABICYCLO[2.2.2]OCTANE; NEUROKININ 1 RECEPTOR; RECEPTOR; SUBSTANCE P;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; HEART LEFT ATRIUM PRESSURE; LUNG CONGESTION; MALE; MICROVASCULATURE; NONHUMAN; PRIORITY JOURNAL; PULMONARY VEIN; RABBIT; RECEPTOR BLOCKING; TRACHEA PRESSURE;

EID: 0029968753     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1996.sp021378     Document Type: Article

References (35)

1. BONHAM, A. C., RAVI, K., WILSON, C. G., ZHANG, Z. & KAPPAGODA, C.T. (1995). Pulmonary venous congestion augments respiratory motoneuronal responses to cigarette smoke in rabbit. Journal of Applied Physiology 78, 1145-1157.
2. COLERIDGE, H. M. & COLERIDGE, J, C. G. (1994). Pulmonary reflexes: neural mechanisms of pulmonary defense. Annual Review of Physiology 56, 69-91.
3. COLERIDGE, H. M., COLERIDGE, J. C. G., GINZEL, K. H., BAKER, D. G., BANZEFF, R. B. & MORRISON, M. A. (1976). Stimulation of 'irritant' receptors and afferent C-fibres in the lungs by prostaglandins. Nature 264, 451-453.
4. COLERIDGE, J. C. G., COLERIDGE, H. M., SCHELEGLE, E. S. & GREEN, J. F. (1993). Acute inhalation of ozone stimulates bronchial C-fibers and rapidly adapting receptors in dogs. Journal of Applied Physiology 74, 2345-2352.
5. DAS, R. M., JEFFERY, P. K. & WIDDICOMBE, J. G. (1978). The epithelial innervation of the lower respiratory tract of the cat. Journal of Anatomy 126, 123-131.
6. DAS, R, M., JEFFREY, P. K. & WIDDICOMBE, J. G. (1979). Experimental degeneration of intra-epithelial nerve fibres in cat airways. Journal of Anatomy 128, 259-267.
7. DELAY-GOYET, P. & LUNDBERG, J. M. (1991). Cigarette smoke-induced airway edema is blocked by the NK1 antagonist, CP-96,345. European Journal of Pharmacology 203, 157-158.
8. 1 receptors. European Journal of Pharmacology 209, 277-279.
9. HARGREAVES, M., RAVI, K. & KAPPAGODA, C. T. (1991). Responses of slowly and rapidly adapting receptors in the airways of rabbits to changes in the Starling forces. Journal of Physiology 432, 81-97.
10. HARGREAVES, M., RAVI, K. & KAPPAGODA, C. T. (1993). Effect of bradykinin on respiratory rate in anaesthetized rabbits; role of rapidly adapting receptors. Journal of Physiology 468, 501-513.
11. HARGREAVES, M., RAVI, K., SENARATNE, M. P. J. & KAPPAGODA, C. T. (1992). Responses of rapidly adapting receptors to bradykinin before and after administration of enalapril in rabbits. Clinical Science 83, 399-407.
12. KAPPAGODA, C. T., MAN, G. C. W. & TEO, K. K. (1987). Behaviour of canine pulmonary vagal afferent receptors during sustained acute pulmonary venous pressure elevation. Journal of Physiology 394, 249-265.
13. KAPPAGODA, C. T. & RAVI, K. (1989). Plasmapheresis affects responses of slowly and rapidly adapting airway receptors to pulmonary venous congestion in dogs. Journal of Physiology 416, 79-91.
14. KARLSSON, J., SANT' AMBROGIO, G. & WIDDICOMBE, J. G. (1988). Afferent neural pathways in cough and bronchoconstriction. Journal of Applied Physiology 65, 1007-1023.
15. 1 receptor antagonist. British Journal of Pharmacology 105, 261-262.
16. LEI, Y., BARNES, P. J. & ROGERS, D. F. (1995). Mechanisms and modulation of airway plasma exudation after direct inhalation of cigarette smoke. American Journal of Respiratory and Critical Care Medicine 151, 1752-1762.
17. LEMBECK, F., DONNERER, J., TSUCHIYA, M. & NAGAHISA, A. (1992). The non-peptide tachykinin antagonist, CP-96,345, is a potent inhibitor of neurogenic inflammation. British Journal of Pharmacology 105, 527-530.
18. LUNDBERG, J. M., MARTLING, C.-R., SARIA, A., FOLKERS, K. & ROSELL, S. (1983). Cigarette smoke-induced airway oedema due to activation of capsaicin-sensitive vagal afferents and substance P release. Neuroscience 10, 1361-1368.
19. MAGGI, C. A., GIACHETTI, A., DEY, R. D. & SAID, S. I. (1995). Neuropeptides as regulators of airway function: Vasoactive intestinal peptide and the tachykinins. Physiological Reviews 76, 277-322.
20. MATSUMOTO, S., YAMASAKI, M., KANNO, T., NAGAYAMA, T., TANNO, M. & SHIMIZU, T. (1994). Substance P antagonist does not block the stimulation of rapidly adapting pulmonary stretch receptors by ammonia. Lung 172, 31-45.
21. NGUYEN, L. S., VILLABLANCA, A. C. & RUTLEDGE, J. C. (1995). Substance P increases microvascular permeability via nitric oxide-mediated connective pathways. American Journal of Physiology 268, R1060-1068.
22. PRABHAKAR, N. R., RUNOLD, M., YAMAMOTO, Y, LANGERCRANTZ, H., CHERNIACK, N. S. & EULER, C. V. (1987). Role of the vagal afferents in substance P-induced respiratory responses in anaesthetized rabbits. Acta Physiologica Scandinavica 131, 63-71.
23. RAVI, K., BONHAM, A. C. & KAPPAGODA, C. T. (1994a). Effect of pulmonary lymphatic obstruction on respiratory rate and airway rapidly adapting receptor activity in rabbits. Journal of Physiology 480, 163-170.
24. RAVI, K. & KAPPAGODA, C. T. (1990). Reflex effects of pulmonary venous congestion: Role of vagal afferents. News in Physiological Sciences 5, 95-99.
25. RAVI, K. & KAPPAGODA, C. T. (1992). Responses of pulmonary C-fibre and rapidly adapting receptors to pulmonary edema in dogs. Canadian Journal of Physiology and Pharmacology 70, 68-76.
26. RAVI, K., KAPPAGODA, C. T. & BONHAM, A. C. (1994b). Pulmonary congestion enhances responses of lung rapidly adapting receptors to cigarette smoke in rabbit. Journal of Applied Physiology 77, 2633-2640.
27. SELLICK, H. & WIDDICOMBE, J. G. (1971). Stimulation of lung irritant receptors by cigarette smoke, carbon dust, and histamine aerosol. Journal of Applied Physiology 31, 15-19.
28. SKEPPER, J. N., KAPPAGODA, C. T., MCNAUCHTON, L. & NAVARATNAM, V. (1990). Morphology of presumptive rapidly adapting receptors in the rat bronchus. Journal of Anatomy 168, 265-276.
29. 1) receptor. Science 251, 436-437.
30. TURNER, C. R., STOW, R. B., HUBBS, S. J., GOMES, B. C. & WILLIAMS, J. C. (1993). Acrolein increases airway sensitivity to substance P and decreases NEP activity in guinea pigs. Journal of Applied Physiology 74, 1830-1839.
31. 1 receptor antagonist, has non-specific actions on neurotransmission. British Journal of Pharmacology 107, 762-765.
32. WIDDICOMBE, J. G. (1954). Receptors in the trachea and bronchi of the cat. Journal of Physiology 123, 71-104.
33. WIDDICOMBE, J. G. (1977). Respiratory reflexes and defense. In Respiratory Defense Mechanisms, ed. BRAIN, J. D., PROCTOK, D. F. & REID, L. M., pp. 593-630. Dekker, New York.
34. WIDDICOMBE, J. G. (1995). Neurophysiology of the cough reflex. European Respiratory Journal 8, 1193-1202.
35. 11]-substance P. Neuropeptides 28, 35-42.