The enantiomers of tramadol and its major metabolite inhibit peristalsis in the guinea pig small intestine via differential mechanisms

BMC Pharmacology

Volumn 7, Issue , 2007, Pages

  Herbert, Michael K ^a   Weis, Rebecca ^a   Holzer, Peter ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTOR; ADRENERGIC RECEPTOR BLOCKING AGENT; DRUG METABOLITE; METHYSERGIDE; NALOXONE; O NORTRAMADOL; OPIATE RECEPTOR; PRAZOSIN; SEROTONIN ANTAGONIST; TRAMADOL; TROPISETRON; UNCLASSIFIED DRUG; YOHIMBINE; DRUG DERIVATIVE; O DEMETHYLTRAMADOL; O-DEMETHYLTRAMADOL;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; ENANTIOMER; FEMALE; GUINEA PIG; IN VITRO STUDY; INHIBITION KINETICS; INTESTINE DISTENSION; INTESTINE MOTILITY; INTESTINE PERFUSION; INTESTINE PRESSURE; MALE; NONHUMAN; SMALL INTESTINE; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; METABOLISM; PERISTALSIS; PHYSIOLOGY; STEREOISOMERISM;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GUINEA PIGS; INTESTINE, SMALL; MALE; PERISTALSIS; STEREOISOMERISM; TRAMADOL;

EID: 34047111768     PISSN: None     EISSN: 14712210     Source Type: Journal    
DOI: 10.1186/1471-2210-7-5     Document Type: Article

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