Efficacy and tolerability of sustained-release tramadolin the treatment of symptomatic osteoarthritis of the hip or knee: A multicenter, randomized, double-blind, placebo-controlled study

Clinical Therapeutics

Volumn 26, Issue 11, 2004, Pages 1774-1782

  Malonne, Hugues ^a,c   Coffiner, Monte ^b   Sonet, Bernard ^b   Sereno, Antoine ^b   Vanderbist, Francis ^b  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b Laboratoires SMB SA   (Belgium)

^c Campu Plaine CP206 3   (Belgium)

Author keywords

tramadol osteoarthritis once daily efficacy pain

Indexed keywords

TRAMADOL;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; ASTHENIA; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; DIARRHEA; DIZZINESS; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; EPIGASTRIC PAIN; FEMALE; HEADACHE; HEARTBURN; HIP OSTEOARTHRITIS; HUMAN; HYPERHIDROSIS; KNEE OSTEOARTHRITIS; MAJOR CLINICAL STUDY; MALAISE; MALE; NAUSEA; SIDE EFFECT; SOMNOLENCE; SUSTAINED DRUG RELEASE; VISUAL ANALOG SCALE; VOMITING;

AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; CHRONIC DISEASE; DELAYED-ACTION PREPARATIONS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; OSTEOARTHRITIS, HIP; OSTEOARTHRITIS, KNEE; TRAMADOL;

EID: 11844294095     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2004.11.005     Document Type: Article

References (22)

1. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 Update Arthritis Rheum 43 2000 1905 1915
2. Jordan K.M., Arden N.K., and Doherty M. Standing Committee for International Clinical Studies Including Therapeutic Trials EULAR Recommendations 2003: An evidence based approach to the management of knee osteoarthritis: Report of a Task Force of the Standing Committeefor International Clinical Studies Including Therapeutic Trials (ESCISIT) Ann Rheum Drs. 62 2003 1145 1155
3. Cancer Pain Relief 1984 World Health Organization Geneva
4. Bannwarth B. Risk benefit assessment of opioids in chronic noncancer pain Drug Saf. 21 1999 283 296
5. Jamison R.N., Schein J.R., and Vallow S. Neuropsychological effects of long-term opioid use in chronic pain patients J Pain Symptom Manage 26 2003 913 921
6. Kjaersgaard-Andersen P., Nafei A., and Skov O. Codeine plus paracetamol versus paracetamol in longer- term treatment of chronic paindue to osteoarthritis of the hip. A randomised, double-blind, multi-centre study Pain 43 1990 309 318
7. Portenoy R.K. Current pharmacotherapy of chronic pain J Pain Symptom Manage. 19 Suppl 1 2000 516 520
8. [in French] Collart L., Luthy C., Favario-Constantin C., and Dayer P. Duality of the analgesic effect of tramadol in humans Schweiz Med Wochenschr. 123 1993 2241 2243
9. Dayer P., Collart L., and Desmeules J. The pharmacology of tramadol Drugs 47 Suppl 1 1994 3 7
10. Desmeules J.A., Piguet V., Collart L., and Dayer P. Contribution of monoaminergic modulation to the analgesic effect of tramadol Br J Clin Pharmacol 41 1996 7 12
11. Raffa R.B., Friderichs E., and Reimann W. Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic J Pharmacol Exp Ther. 260 1992 275 285
12. Raffa R.B., Friderichs E., and Reimann W. Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol J Pharmacol Exp Ther. 267 1993 331 340
13. Ehrenreich H., and Poser W. Dependence on tramadol Clin Investig. 72 1993 76
14. Knisely J.S., Campbell E.D., Dawson K.S., and Schnoll S.H. Tramadol post-marketing surveillance in health care professionals Drug Alcohol Depend. 68 2002 15 22
15. Preston K.L., Jasinski D.R., and Testa M. Abuse potential and pharmacological comparison of tramadol and morphine Drug Alcohol Depend. 27 1991 7 17
16. Klotz U. Tramadol - the impact of its pharmacokinetic and pharmacodynamic properties on the clinical management of pain Arzneimittelforschung 53 2003 681 687
17. Malonne H., Sonet B., and Streel B. Pharmacokinetic evaluation of a new oral sustained release dosage form of tramadol Br J Clin Pharmacol. 57 2004 270 278
18. Huskisson E.C. Measurement of pain Lancet 2 1974 1127 1131
19. [published corrections appear in Scand J Rheumatol. 1988;1 Tfollowing 241 and Scand J Rheumatol Suppl. 1988;73:1] Lecluesne M.G., Mery C., Samson M., and Gerard P. Indexes of severity for osteoarthritis of the hip and knee. Validation-value in comparison with other assess ment tests Scand J Rheumatol Suppl. 65 1987 85 89
20. Adler L., McDonald C., O'Brien C., and Wilson M. A comparison of once-daily tramadol with normal release tramadol in the treatment of pain in osteoarthritis J Rheumatol. 29 2002 2196 2199
21. Bodalia B., McDonald C.J., and Smith K.J. A comparison of the pharmacokinetics, clinical efficacy, and tolerability of once-daily tramadol tablets with normal release tramadol capsules J Pain Symptom Manage. 25 2003 142 149
22. Katz W.A. Pharmacology and clinical experience with tramadol in osteoarthritis Drugs 52 Suppl 3 1996 39 47