Genotoxicity (mitotic recombination) of the cancer chemotherapeutic agents cisplatin and cytosine arabinoside in Aspergillus nidulans

Food and Chemical Toxicology

Volumn 45, Issue 6, 2007, Pages 1091-1095

  Miyamoto, C T ^a   Sant'Anna, J R ^a   Franco, C C S ^a   Castro Prado, M A A ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

Author keywords

Antineoplastic agents; Second malignances; Somatic recombination; Tumor promoters

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; CYTARABINE;

ARTICLE; ASPERGILLUS NIDULANS; CANCER PATIENT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIPLOIDY; FUNGAL STRAIN; GENE LOCUS; GENETIC MARKER; GENOTOXICITY; HETEROZYGOSITY; HETEROZYGOSITY LOSS; HOMOZYGOSITY; MALIGNANT NEOPLASTIC DISEASE; MITOTIC RECOMBINATION; NONHUMAN; PROMOTER REGION; TUMOR SUPPRESSOR GENE;

4-AMINOBENZOIC ACID; ANTINEOPLASTIC AGENTS; ASPERGILLUS NIDULANS; BIOTIN; CISPLATIN; CYTARABINE; HUMANS; LOSS OF HETEROZYGOSITY; METHIONINE; MUTAGENICITY TESTS; PYRIDOXINE; RECOMBINATION, GENETIC; RIBOFLAVIN;

ARA; EMERICELLA NIDULANS;

EID: 33947731232     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2006.12.018     Document Type: Article

References (34)

1. Arnaudeau C., Tenorio Miranda E., Jenssen D., and Helleday T. Inhibition of DNA synthesis is a potent mechanism by which cytostatic drugs induce homologous recombination in mammalian cells. Mutat. Res. 461 (2000) 221-228
2. Aung L., Gorlick R.G., Shi W., Thaler H., Shorter N.A., Healey J.H., Huvos A.G., and Meyers P.A. Second malignant neoplasms in long-term survivors of osteosarcoma. Cancer 95 (2002) 1728-1734
3. Becker T.C.A., and Castro-Prado M.A.A. Parameiosis in Aspergillus nidulans in response to doxorubicin. Folia Microbiol. 49 6 (2004) 699-704
4. Bergen G.G., and Morris N.R. Kinetics of the nuclear division cycle of Aspergillus nidulans. J. Bacteriol. 156 (1983) 155-160
5. Bishop A.J.R., and Schiestl R.H. Homologous recombination and its role in carcinogenesis. J. Biomed. Biotechnol. 2 (2002) 75-85
6. Cariello N.F., Swenberg J.A., and Skopek T.R. In vitro mutational specificity of cisplatin in the human hypoxanthine guanine phosphoribosyltransferase gene. Cancer Res. 52 (1992) 2866-2873
7. Chiuchetta S.J.R., and Castro-Prado M.A.A. Genotoxic evaluation of sodium nitroprusside in Aspergillus nidulans. Genet. Mol. Biol. 28 (2005) 798-803
8. Cunha K.S., Reguly M.L., Graf U., and Andrade H.H.R. Somatic recombination: a major genotoxic effect of two pyrimidine antimetabolotic chemotherapeutic drugs in Drosophila melanogaster. Mutat. Res. 514 (2002) 95-103
9. Frankenberg-Schwager M., Kirchermeier D., Greif G., Baer K., Becker M., and Frankenberg D. Cisplatin-mediated DNA double-strand breaks in replicating but not in quiescent cell on yeast Saccharomyces cerevisiae. Toxicology 212 (2005) 175-184
10. Galli A., and Schiestl R.H. Effects of DNA double-strand and single-strand breaks on intrachromosomal recombination events in cell-cycle-arrested yeast cells. Genetics 149 (1998) 1235-1250
11. Geller H.M., Cheng K.Y., Goldsmith N.K., Romero A.A., Zhang A.L., Morris E.J., and Grandison L. Oxidative stress mediates neuronal DNA damage and apoptosis in response to cytosine arabinoside. J. Neurochem. 78 (2001) 265-275
12. Gokel Y., and Paydas S. Chronic myeloid leukemia in a patient with colon adenocarcinoma. Haematologia 32 (2002) 501-503
13. Grant S. Ara-C: cellular and molecular pharmacology. Adv. Cancer Res. 72 (1998) 197-233
14. Helleday T. Pathways for mitotic homologous recombination in mammalian cells. Mutat. Res. 532 (2003) 103-115
15. Imreh S., Klein G., and Zabarovskv E.R. Search for unknown tumor-antagonizing genes. Gene. Chromosome. Canc. 38 (2003) 307-321
16. Jones E., Secord A., Prosnitz L.R., Samulski T.V., Oleson J.R., Berchuck A., Clarke-Pearson D., Soper J., Dewhirst M.W., and Vujaskovic Z. Intra-peritoneal cisplatin and whole abdomen hyperthermia for relapsed ovarian carcinoma. Int. J. Hyperthermia 22 (2006) 161-172
17. Kaneshima E.N., and Castro-Prado M.A.A. Benznidazole-induced genotoxicity in diploid cells of Aspergillus nidulans. Mem. Inst. Oswaldo Cruz 1000 (2005) 325-329
18. Kufe D.W., Major P.P., Egan E.M., and Beardsley G.P. Correlation of cytotoxicity with incorporation of ara-C into DNA. J. Biol. Chem. 255 (1980) 8997-9000
19. Larminat F., and Bohr V. Role of the human ERCC-1 gene in gene-specific repair of cisplatin-induced DNA damage. Nucleic Acids Res. 22 (1994) 3005-3010
20. Lasko D., Cavenee W., and Nordenskjöld M. Loss of constitutional heterozygosity in human cancer. Annu. Rev. Genet. 25 (1991) 281-314
21. Lin X., and Howell S.B. DNA mismatch repair and p53 function are major determinants of the rate of development of cisplatin resistance. Mol. Cancer Ther. 5 (2006) 1239-1247
22. Lo T., Pellegrini L., Venkitaraman A.R., and Blundell T.L. Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer. DNA Repair 2 (2003) 1015-1028
23. Moynahan M.E., and Jasin M. Loss of heterozygosity induced by a chromosomal double-strand break. Proc. Natl. Acad. Sci. USA 94 (1997) 8988-8993
24. Nakayama T., Sakamoto S., Sassa S., Suzuki S., Kudo H., and Nagasawa H. Paradoxical effect of cytosine arabinoside on mouse leukemia cell line L1210 cells. Anticancer Res. 25 (2005) 157-160
25. Roper J.A. Production of heterozygous diploids in filamentous fungi. Experientia 8 (1952) 14-15
26. Smith M.A., Rubinstein L., and Ungerleider R.S. Therapy-related acute myeloid leukemia following treatment with epipodophyllotoxins: estimating the risks. Med. Pediatr. Oncol. 23 (1994) 86-98
27. Theodore C., Bayle C., Bernheim A., and Wibauld P. Secondary leukaemia after treating advanced bladder cancer with methotrexate, vinblastine, doxirubicin and cisplatin chemotherapy. BJU Int. 90 (2002) 470-471
28. Tischfield J.A. Loss of heterozygosity or: how I learned to stop worrying and love mitotic recombination. Am. J. Hum. Genet. 61 (1997) 995-999
29. Turnbull D., Popescu N.C., DiPaolo J.A., and Myhr B.C. Cis-platinum(II) diamine dichloride causes mutation, transformation, and sister-chromatid exchange in cultured mammalian cells. Mutat. Res. 66 (1979) 267-275
30. Vancura R.W., Kepes J.J., Newell K.L., Ha T.M., and Arnold P.M. Secondary intracranial neoplasms exhibiting features of astrocytoma and neuroblastoma in 2 children treated for acute lymphoblastic leukemia: report of 2 cases. Surg. Neurol. 65 (2006) 490-494
31. Weinberg R. Tumor suppressor genes. Science 254 (1991) 1138-1146
32. Yamada T., Shinohara K., Takeda K., Kamed N., Katsuki K., Ariyoshi K., and Kamei T. Second lung adenocarcinoma after combination chemotherapy in two patients with primary non-Hodgkin's lymphoma. Jpn. J. Clin. Oncol. 29 (1999) 226-228
33. Yarema K.J., Lippard S.J., and Essigmann J.M. Mutagenic and genotoxic effects of DNA adducts formed by the anticancer drug cis-diamminedichloroplatinum(II). Nucleic Acids Res. 23 (1995) 4067-4072
34. Young B.D., Debernardi S., Lillington D.M., Skoulakis S., Chaplin T., Foot N.J., and Raghavan M. A role for mitotic recombination in leukemogenesis. Adv. Enzyme Regul. 46 (2006) 90-97