Secondary leukaemia after treating advanced bladder cancer with methotrexate, vinblastine, doxorubicin and cisplatin chemotherapy and radiotherapy

BJU International

Volumn 90, Issue 4, 2002, Pages 470-471

  Theodore, C ^a   Bayle, C ^a   Bernheim, A ^a   Wibault, P ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; ANTHRACYCLINE; ANTINEOPLASTIC AGENT; CISPLATIN; DOXORUBICIN; METHOTREXATE; VINBLASTINE;

ACUTE GRANULOCYTIC LEUKEMIA; ADJUVANT CHEMOTHERAPY; AGED; ARTICLE; BLADDER CANCER; BLOOD CELL COUNT; BONE MARROW TOXICITY; CANCER DIAGNOSIS; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURGERY; CASE REPORT; CHROMOSOME BAND; CHROMOSOME DELETION; CYSTECTOMY; HUMAN; IN SITU HYBRIDIZATION; KARYOTYPE; LYMPHOCYTE; MONOCYTE; PANCYTOPENIA; PRIORITY JOURNAL; RADIATION DOSE; UROGENITAL TRACT TUMOR;

ACUTE DISEASE; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CISPLATIN; DOXORUBICIN; HUMANS; LEUKEMIA, MYELOID; MALE; METHOTREXATE; NEOPLASMS, SECOND PRIMARY; URINARY BLADDER NEOPLASMS; VINBLASTINE;

EID: 0036968160     PISSN: 14644096     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-410X.2002.02866.x     Document Type: Article

References (8)

1. Sternberg CN, Yagoda A, Scher HI et al. MAC (methotrexate, vinblastine, doxorubicin and cisplatin) for advanced transitional cell carcinoma of the urothelium. J Urol 1988; 139: 461-9
2. Hunger S, Tkachuk D, Amylon M et al. HRX involvement in de novo and secondary leukemias with diverse chromosome 11q23 abnormalities. Blood 1993; 81: 3197-20
3. Pedersen-Bjergaard J, Sigsgaard TC, Nielson D et al. Acute monocytic or myelomonocytic leukemia with balanced chromosomal translocation to band 11q23 after therapy with 4-epidoxorubicin and cisplatin or cyclophosphamide for breast cancer. J Clin Oncol 1992; 10: 1444-51
4. Travis LB, Holowathy EJ, Bergfelt K et al. Risk of leukemia after platinum based chemotherapy for ovarian cancer. N Eng J Med 1999; 340: 351-7
5. Sternberg CN, de Mulder PHM, Shornagel JH et al. Randomized phase III trial of high dose intensity methotrexate, vin-blastine, doxorubicin and cisplatin (M-VAC) chemotherapy and recombinant human granulocyte colony stimulating factor versus classic M-VAC in advanced urothelial tract tumors: European Organization for Research and Treatment of Cancer Protocol, 30924. J Clin Oncol 2001; 19: 2638-46
6. Natale RB, Grossman HB, Blumenstein Bet al. SWOG 8710 (INT-0080). Randomized phase III trial of neoadjuvant M-VAC + cystectomy versus cystectomy alone in patients with locally advanced bladder cancer. Proc ASCO 2001. J Clin Oncol 2001; 20: 2
7. Thirman M, Larson RA. Therapy related myeloid leukemia. Hematol Oncol North Am 1996; 10: 293
8. Zietman AL, Shipley WU, Kaufman DS. Organ-conserving approaches to muscle-invasive bladder cancer: future alternatives to radical cystectomy. Ann Med 2000; 32: 34-42