Multiple sclerosis and anti-Plasmodium falciparum innate immune response

Journal of Neuroimmunology

Volumn 185, Issue 1-2, 2007, Pages 201-207

  Sotgiu, Stefano ^a   Sannella, Anna R ^b   Conti, Bruno ^c   Arru, Giannina ^a   Fois, Maria Laura ^a   Sanna, Alessandra ^a   Severini, Carlo ^b   Morale, Maria Concetta ^c,d   Marchetti, Bianca ^a,d   Rosati, Giulio ^a   Musumeci, Salvatore ^a,e  

^a UNIVERSITY OF SASSARI   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d OASI RESEARCH INSTITUTE IRCCS   (Italy)

^e CNR   (Italy)

Author keywords

HLA; Malaria; Multiple sclerosis; Plasmodium falciparum; TNF

Indexed keywords

CYTOKINE; HLA ANTIGEN CLASS 2; HLA DR ANTIGEN; INTERLEUKIN 12; INTERLEUKIN 6; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ALLELE; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE PREDISPOSITION; ETHNICITY; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC TRAIT; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INNATE IMMUNITY; ITALY; MALARIA; MALE; MULTIPLE SCLEROSIS; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROMOTER REGION;

ADULT; ANIMALS; CELL PROLIFERATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HLA-DR ANTIGENS; HUMANS; IMMUNITY, NATURAL; INTERLEUKIN-12 SUBUNIT P40; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; MALARIA; MALE; MULTIPLE SCLEROSIS; PLASMODIUM FALCIPARUM; POLYMORPHISM, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33947675304     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2007.01.020     Document Type: Article

References (43)

1. Allen S.J., O'Donnell A., Alexander N.D., Alpers M.P., Peto T.E., Clegg J.B., and Weatherall D.J. Alpha-thalassemia protects children against disease caused by other infections as well as malaria. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 14736-14741
2. Bitti P.P., Murgia B.S., Ticca A., Ferrai R., Musu L., Piras M.L., Puledda E., Campo S., Durando S., Montomoli C., Clayton D.G., Mander A.P., and Bernardinelli L. Association between the ancestral haplotype HLA A30-B18-DR3 and multiple sclerosis in central Sardinia. Genet. Epidemiol. 20 (2001) 271-283
3. Brown P.J. New considerations on the distribution of malaria, thalassemia and glucose-6-phosphate dehydrogenase deficiency in Sardinia. Hum. Biol. 53 (1981) 367-382
4. Brown P.J. Failure-as-success: Multiple meanings of eradication in the Rockefeller Foundation Sardinia project, 1946-1951. Parassitologia 40 (1998) 117-130
5. Butcher G.A. Does malaria select for predisposition to autoimmune disease?. J. R. Soc. Med. 84 (1991) 451-453
6. Cavalli Sforza L.L., and Bodmer W.F. The Genetics of Human Populations (1971), Freeman, San Francisco
7. Chakravarti A. Population genetics - making sense out of sequence. Nat. Genet. 22 (1999) 239-247
8. Deininger M.H., Kremsner P.G., Meyermann R., and Schluesener H. Macrophages/microglial cells in patients with cerebral malaria. Eur. Cytokine Netw. 13 (2002) 173-185
9. Delasnerie-Laupretre N., and Alperovitch A. Childhood infections in multiple sclerosis: a study of North African-born patients who migrated to France. The French Collaborative Group on Multiple Sclerosis. Neuroepidemiology 9 (1990) 118-123
10. Fernandez-Arquero M., Arroyo R., and Rubio A. Primary association of a TNF gene polymorphism with susceptibility to multiple sclerosis. Neurology 53 (1999) 1361-1363
11. Flint J., Hill A.V., Bowden D.K., Oppenheimer S.J., Sill P.R., Serjeantson S.W., Bana-Koiri J., Bhatia K., Alpers M.P., Boyce A.J., et al. High frequencies of alpha-thalassaemia are the result of natural selection by malaria. Nature 321 (1986) 744-750
12. Haldane J.B.S. The rate of mutation of human genes. Hereditas 35 (1949) 267-273 (suppl.)
13. Hendriks J.A., Teunissen C.E., de Vries H.E., and Dijkstra C.D. Macrophages and neurodegeneration. Brain Res. Rev. 48 (2005) 185-195
14. Hill A.V., Allsopp C.E., Kwiatkowski D., Anstey N.M., Twumasi P., Rowe P.A., Bennett S., Brewster D., McMichael A.J., and Greenwood B.M. Common West African HLA antigens are associated with protection from severe malaria. Nature 352 (1991) 595-600
15. Hohlfeld R., and Wekerle H. Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy: from pipe dreams to (therapeutic) pipelines. Proc. Natl. Acad. Sci. U. S. A. 101 Suppl 2 (2004) 14599-14606
16. Kaneko A., Taleo G., Kalkoa M., Yamar S., Kobayakawa T., and Björkman A. Malaria eradication on islands. Lancet 356 (2000) 1560-1564
17. Knight J.C., Udalova I., Hill A.V., Greenwood B.M., Peshu N., Marsh K., and Kwiatkowski D. A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria. Nat. Genet. 22 (1999) 145-150
18. Kurtzke J.F., Delasnerie-Laupretre N., and Wallin M.T. Multiple sclerosis in North African migrants to France. Acta Neurol. Scand. 98 (1998) 302-309
19. Lassmann H., Bruck W., and Lucchinetti C. Heterogeneity of multiple sclerosis pathogenesis: Implications for diagnosis and therapy. Trends Mol. Med. 7 (2001) 115-121
20. Lincoln M.R., Montpetit A., Cader M.Z., Saarela J., Dyment D.A., Tiislar M., Ferretti V., Tienari P.J., Sadovnick A.D., Peltonen L., Ebers G.C., and Hudson T.J. A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis. Nat. Genet. 37 10 (2005) 1108-1112
21. Makler M.T., and Hinrichs D.J. Measurement of lactate dehydrogenase activity of Plasmodium falciparum as an assessment of parasitemia. Am. J. Trop. Med. Hyg. 48 (1993) 205-210
22. Malaguamera L., and Musumeci S. The immune response to Plasmodium falciparum malaria. Lancet Infect. Dis. 2 (2002) 472-478
23. Marrosu M.G., Murru M.R., Costa G., Cucca F., Sotgiu S., Rosati G., and Muntoni F. Multiple Sclerosis in Sardinia is associated and in linkage-disequilibrium with HLA-DR3 and-DR4 alleles. Am. J. Hum. Gen. 61 (1997) 454-457
24. McGuire W., Knight J.C., Hill A.V., Allsopp C.E., Greenwood B.M., and Kwiatkowski D. Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles. J. Infect. Dis. 179 (1999) 287-290
25. Modiano D., Luoni G., Sirima B.S., Simporé J., Verra F., Konaté A., Rastrelli E., Olivieri A., Calissano C., Pagnoti G.M., D'urbano L., Sanou I., Sawadogo A., Modiano G., and Coluzzi M. Haemoglobin C protects against clinical Plasmodium falciparum malaria. Nature 414 (2001) 305-308
26. Poser C.M., Paty D.W., Scheinberg L., McDonald W.I., Davis F.A., Ebers G.C., Johnson K.P., Sibley W.A., Silberberg D.H., and Tourtellotte W.W. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann. Neurol. 13 (1983) 227-231
27. Pugliatti M., Sotgiu S., and Rosati G. The worldwide prevalence of multiple sclerosis. Clin. Neurol. Neurosurg. 104 (2002) 182-191
28. Pugliatti M., Sotgiu S., Solinas G., Castiglia P., Pirastru M.I., Murgia B., Mannu L., Sanna G., and Rosati G. Multiple sclerosis epidemiology in Sardinia: evidence for a true increasing risk. Acta Neurol. Scand. 103 (2001) 20-26
29. Pugliatti M., Riise T., Sotgiu M.A., Sotgiu S., Satta W.M., Mannu L., Sanna G., and Rosati G. Increasing incidence of multiple sclerosis in the province of Sassari, Northern Sardinia. Neuroepidemiology 25 (2005) 129-134
30. Pugliatti M., Riise T., Sotgiu M.A., Satta W.M., Sotgiu S., Pirastru M.I., and Rosati G. Evidence of early childhood as the susceptibility period in multiple sclerosis: space-time cluster analysis in a Sardinian population. Am. J. Epidemiol. 164 4 (2006) 326-333
31. Rosati G., Aiello I., Granieri E., Pirastru M.I., Becciu S., Demontis G., Mannu L., and Zoccheddu A. Incidence of multiple sclerosis in Macomer, Sardinia, 1912-1981: onset of disease after 1950. Neurology 36 (1986) 14-19
32. Ruwende C., Khoo S.C., Snow R.W., Yates S.N., Kwiatkowski D., Gupta S., Warn P., Allsopp C.E., Gilbert S.C., Peschu N., et al. Natural selection of hemi- and heterozygotes for G6PD deficiency in Africa by resistance to severe malaria. Nature 376 (1995) 246-249
33. Schmidt S., Papassotiropoulos A., Sotgiu S., Kolsch H., Arru G., Fois M.L., Haase C.G., Schmitz S., Konig N., Harzheim M., Heun R., and Klockgether T. Investigation of a genetic variation of a variable number tandem repeat polymorphism of interleukin-6 gene in patients with multiple sclerosis. J. Neurol. 250 (2003) 607-611
34. Siniscalco M., Bernini L., Latte B., et al. Favism and thalassaemia in Sardinia and their relationship to malaria. Nature 190 (1961) 1179-1180
35. Sotgiu S., Pugliatti M., Serra C., Rosati G., Dolei A., and Marrosu M.G. TNF2 allele does not contribute to increased TNF-α production in Sardinian multiple sclerosis. Ann. Neurol. 46 (1999) 799-800
36. Sotgiu S., Pugliatti M., Serra C., Deiana G.A., Dolei A., Marrosu M.G., and Rosati G. Cytokines and multiple sclerosis severity: no correlation among Sardinians. Ann. Neurol. 48 (2000) 816
37. Sotgiu S., Pugliatti M., Sotgiu A., Sanna A., and Rosati G. Does the "hygiene hypothesis" provide an explanation for the high prevalence of multiple sclerosis in Sardinia?. Autoimmunity 36 (2003) 257-260
38. Sotgiu S., Pugliatti M., Fois M.L., Arru G., Sanna A., Sotgiu M.A., and Rosati G. Genes, environment, and susceptibility to multiple sclerosis. Neurobiol. Dis. 17 (2004) 131-143
39. Trager W., and Jensen J.B. Human malaria parasites in continuous culture. Science 193 (1976) 673-675
40. Wallach M. Efficient extraction and translation of Plasmodium falciparum messenger RNA. Mol. Biochem. Parasitol. 6 (1982) 335-342
41. Walliker D., Quakyi I.A., Wellems T.E., McCutchan T.F., Szarfman A., London W.T., Corcoran L.M., Burkot T.R., and Carter R. Genetic analysis of the human malaria parasite Plasmodium falciparum. Science 236 (1987) 1661-1666
42. Wirz S.A., Morale M.C., Marchetti B., Barr A.M., Sotgiu S., Rosati G., Pugliatti M., Sanna M.V., Giliberto O., Bartfai T., and Conti B. High Frequency of TNF Alleles-238A and-376A in Individuals from Northern Sardinia. Cytokine 26 (2004) 149-154
43. Yazdanbakhsh M., Kremsner P.G., and van Ree R. Allergy, parasites, and the hygiene hypothesis. Science 296 (2002) 490-494