Application of the Suzuki-Miyaura cross-coupling to increase antimicrobial potency generates promising novel antibacterials

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 8, 2007, Pages 2361-2364

  Haug, Bengt Erik ^a,b   Stensen, Wenche ^a,b   Svendsen, John S ^a,b  

^a UNIVERSITY OF TROMSØ   (Norway)

^b LYTIX BIOPHARMA AS   (Norway)

Author keywords

Antibacterial drugs; Cationic antimicrobial peptide; Suzuki Miyaura coupling

Indexed keywords

AMINO ACID DERIVATIVE; ANTIINFECTIVE AGENT; TRIPEPTIDE DERIVATIVE;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; COMPARATIVE STUDY; CROSS COUPLING REACTION; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUZUKI REACTION;

ANIMALS; ANTI-BACTERIAL AGENTS; CALCIUM SIGNALING; DNA-BINDING PROTEINS; HUMANS; INHIBITORY CONCENTRATION 50; MICE; PATCH-CLAMP TECHNIQUES; PHARMACOKINETICS; PROTEIN BINDING; RECEPTORS, SOMATOSTATIN; TRANS-ACTIVATORS;

POSIBACTERIA;

EID: 33947586139     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.12.049     Document Type: Article

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