Altered HDAC5 and CREB mRNA expressions in the peripheral leukocytes of major depression

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 31, Issue 3, 2007, Pages 628-632

  Iga, Jun ichi ^a   Ueno, Shu ichi ^a   Yamauchi, Ken ^a   Numata, Shusuke ^a   Kinouchi, Sawako ^a   Tayoshi Shibuya, Sumiko ^a   Song, Hongwei ^a   Ohmori, Tetsuro ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Calcium signaling; CREB; HDAC5; Leukocyte; Major depression; mRNA expression

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HISTONE DEACETYLASE 5; MESSENGER RNA; PAROXETINE;

ADULT; AGED; ARTICLE; CALCIUM SIGNALING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CREB GENE; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; FEMALE; FOLLOW UP; GENE; GENE EXPRESSION; HDAC5 GENE; HUMAN; LEUKOCYTE; MAJOR DEPRESSION; MALE; PATHOPHYSIOLOGY; QUANTITATIVE ASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; CASE-CONTROL STUDIES; CREB-BINDING PROTEIN; DEPRESSIVE DISORDER, MAJOR; FEMALE; GENE EXPRESSION REGULATION; HISTONE DEACETYLASES; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; PAROXETINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STATISTICS, NONPARAMETRIC;

EID: 33947545662     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2006.12.014     Document Type: Article

References (29)

1. American Psychiatric Association. Quick Reference to the Diagnostic Criteria from DSM-IV (1994)
2. Berton O., and Nestler E.J. New approaches to antidepressant drug discovery: beyond monoamines. Nat Rev Neurosci 7 (2006) 137-151
3. Blendy J.A. The role of CREB in depression and antidepressant treatment. Biol Psychiatry 59 (2006) 1144-1150
4. Bohus M., Forstner U., Kiefer C., Gebicke-Harter P., Timmer J., Spraul G., et al. Increased sensitivity of the inositol-phospholipid system in neutrophils from patients with acute major depressive episodes. Psychiatry Res 65 (1996) 45-51
5. Cassel S., Carouge D., Gensburger C., Anglard P., Burgun C., Dietrich J.B., et al. Fluoxetine and cocaine induce the epigenetic factors MeCP2 and MBD1 in adult rat brain. Mol Pharmacol 70 (2006) 487-492
6. Gallo E.M., Cante-Barrett K., and Crabtree G.R. Lymphocyte calcium signaling from membrane to nucleus. Nat Immunol 7 (2006) 25-32
7. Gottlicher M. Valproic acid: an old drug newly discovered as inhibitor of histone deacetylases. Ann Hematol 83 Suppl 1 (2004) S91-S92
8. Henn F.A., and Vollmayr B. Stress models of depression. Forming genetically vulnerable strains. Neurosci Biobehav Rev 29 (2005) 799-804
9. Iga J., Ueno S., Yamauchi K., Motoki I., Tayoshi S., Ohta K., et al. Serotonin transporter mRNA expression in peripheral leukocytes of patients with major depression before and after treatment with paroxetine. Neurosci Lett 389 (2005) 12-16
10. Iga J., Ueno S., Yamauchi K., Numata S., Motoki I., Tayoshi S., et al. Gene expression and association analysis of LIM (PDLIM5) in major depression. Neurosci Lett 400 (2006) 203-207
11. Irie H., Fujita M., Inokawa Y., and Narita Y. Phase I clinical study of paroxetine HCl (Study 3): pharmacokinetics after single oral administration of paroxetine HCl 10, 20 and 40 mg to healthy adult male volunteers. Jpn Pharmacol Ther 28 (2000) 47-68
12. Jeon S.H., Seong Y.S., Juhnn Y.S., et al. Electroconvulsive shock increases the phosphorylation of cyclic AMP response element binding protein at Ser-133 in rat hippocampus but not in cerebellum. Neuropharmacology 36 (1997) 411-414
13. Lai I.C., Hong C.J., and Tsai S.J. Expression of cAMP response element-binding protein in major depression before and after antidepressant treatment. Neuropsychobiology 48 (2003) 182-185
14. McKinsey T.A., Zhang C.L., Lu J., and Olson E.N. Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. Nature 408 (2000) 106-111
15. Newton S.S., and Duman R.S. Chromatin remodeling: a novel mechanism of psychotropic drug action. Mol Pharmacol 70 (2006) 440-443
16. Newton S.S., Thome J., Wallace T.L., Shirayama Y., Schlesinger L., Sakai N., et al. Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect. J Neurosci 22 (2002) 10883-10890
17. Nibuya M., Nestler E.J., and Duman R.S. Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. J Neurosci 16 (1996) 2365-2372
18. Odagaki Y., Garcia-Sevilla J.A., Huguelet P., La Harpe R., Koyama T., and Guimon J. Cyclic AMP-mediated signaling components are upregulated in the prefrontal cortex of depressed suicide victims. Brain Res 898 (2001) 224-231
19. Pliakas A.M., Carlson R.R., Neve R.L., Konradi C., Nestler E.J., and Carlezon Jr. W.A. Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens. J Neurosci 21 (2001) 7397-7403
20. Raison C.L., and Miller A.H. When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders. Am J Psychiatr 160 (2003) 1554-1565
21. Rocca P., De Leo C., Eva C., Marchiaro L., Milani A.M., Musso R., et al. Decrease of the D4 dopamine receptor messenger RNA expression in lymphocytes from patients with major depression. Prog Neuro-psychopharmacol Biol Psychiatry 26 (2002) 1155-1160
22. Stewart R.J., Chen B., Dowlatshahi D., MacQueen G.M., and Young L.T. Abnormalities in the cAMP signaling pathway in post-mortem brain tissue from the Stanley Neuropathology Consortium. Brain Res Bull 55 (2001) 625-629
23. Thome J., Sakai N., Shin K., et al. cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment. J Neurosci 20 (2000) 4030-4036
24. Tsankova N.M., Berton O., Renthal W., Kumar A., Neve R.L., and Nestler E.J. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci 9 (2006) 519-525
25. Vollmayr B., Sulger J., Gabriel P., and Aldenhoff J.B. Mitogen stimulated rise of intracellular calcium concentration in single T lymphocytes from patients with major depression is reduced. Prog Neuro-psychopharmacol Biol Psychiatry 19 (1995) 1263-1273
26. West A.E., Griffith E.C., and Greenberg M.E. Regulation of transcription factors by neuronal activity. Nat Rev Neurosci 3 (2002) 921-931
27. Williams J.B. A structured interview guide for the Hamilton Depression Rating Scale. Arch Gen Psychiatry 45 (1988) 742-747
28. Yamada S., Yamamoto M., Ozawa H., Riederer P., and Saito T. Reduced phosphorylation of cyclic AMP-responsive element binding protein in the postmortem orbitofrontal cortex of patients with major depressive disorder. J Neural Transm 110 (2003) 671-680
29. Zarate Jr. C.A., Singh J., and Manji H.K. Cellular plasticity cascades: targets for the development of novel therapeutics for bipolar disorder. Biol Psychiatry 59 (2006) 1006-1020