Phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway is essential for neuroendocrine differentiation of prostate cancer

Journal of Biological Chemistry

Volumn 282, Issue 6, 2007, Pages 3571-3583

  Wu, Chengyu ^a   Huang, Jiaoti ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGENS; NEUROENDOCRINE DIFFERENTIATION; PARACRINE MECHANISMS;

CELLS; MAMMALS; ONCOLOGY; PATIENT TREATMENT; TUMORS;

ENZYME INHIBITION;

ADRENALIN; ANDROGEN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C; PROTEIN KINASE;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL DIFFERENTIATION; CELL STRAIN LNCAP; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MALE; NEUROENDOCRINE SYSTEM; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ENZYMOLOGY; METABOLISM; NEUROSECRETION; PATHOLOGY; PHYSIOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

MAMMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL DIFFERENTIATION; CELL LINE, TUMOR; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; NEUROSECRETORY SYSTEMS; PROSTATIC NEOPLASMS; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 33947538812     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608487200     Document Type: Article

References (52)

1. Quinn, M., and Babb, P. (2002) BJU Int. 90, 162-173
2. Sharifi, N., Gulley, J. L., and Dahut, W. L. (2005) J. Am. Med. Assoc. 294, 238-244
3. Balk, S. P. (2002) Urology 60, Suppl. 1, 132-139
4. Visakorpi, T., Hyytinen, E., Koivisto, P., Tanner, M., Keinanen, R., Palmberg, C., Palotie, A., Tammela, T., Isola, J., and Kallioniemi, O. P. (1995) Nat. Genet. 9, 401-406
5. Tan, J., Sharief, Y., Hamil, K. G., Gregory, C. W., Zang, D. Y., Sar, M., Gumerlock, P. H., DeVere White, R. W., Pretlow, T. G., Harris, S. E., Wilson, E. M., Mohler, J. L., and French, F. S. (1997) Mol. Endocrinol. 11, 450-459
6. Gregory, C. W., Johnson, R. T., Jr., Mohler, J. L., French, F. S., and Wilson, E. M. (2001) Cancer Res. 61, 2892-2898
7. Culig, Z., Steiner, H., Bartsch, G., and Hobisch, A. (2005) Endocr.-Relat. Cancer 12, 229-244
8. Vashchenko, N., and Abrahamsson, P. A. (2005) Eur. Urol. 47, 147-155
9. Huang, J., and Di Sant'Agnese, P. A. (2002) in Advances in Oncology: The Expanding Role of Octreotide I (Lamberts, S., and Dogliotti, L., eds) pp. 243-262, BioScientifica Ltd., Bristol, UK
10. Evangelou, A. I., Winter, S. F., Huss, W. J., Bok, R. A., and Greenberg, N. M. (2004) J. Cell. Biochem. 91, 671-683
11. di Sant'Agnese, P. A., de Mesy Jensen, K. L., Churukian, C. J., and Agarwal, M. M. (1985) Arch. Pathol. Lab. Med. 109, 607-612
12. Deleted in proof
13. Burchardt, T., Burchardt, M., Chen, M. W., Cao, Y., de la Taille, A., Shabsigh, A., Hayek, O., Dorai, T., and Buttyan, R. (1999) J. Urol. 162, 1800-1805
14. Cox, M. E., Deeble, P. D., Lakhani, S., and Parsons, S. J. (1999) Cancer Res. 59, 3821-3830
15. Kohn, A. D., Summers, S. A., Birnbaum, M. J., and Roth, R. A. (1996) J. Biol. Chem. 271, 31372-31378
16. Thomas, G. V., Horvath, S., Smith, B. L., Crosby, K., Lebel, L. A., Schrage, M., Said, J., De Kernion, J., Reiter, R. E., and Sawyers, C. L. (2004) Clin. Cancer Res. 10, 8351-8356
17. Chan, J. M., Stampfer, M. J., Ma, J., Gann, P., Gaziano, J. M., Pollak, M., and Giovannucci, E. (2002) J. Natl. Cancer Inst. 94, 1099-1106
18. Cox, M. E., Deeble, P. D., Bissonette, E. A., and Parsons, S. J. (2000) J. Biol. Chem. 275, 13812-13818
19. Webber, M. M., Bello, D., and Quader, S. (1997) Prostate 30, 136-142
20. Kaplan-Lefko, P. J., Chen, T. M., Ittmann, M. M., Barrios, R. J., Ayala, G. E., Huss, W. J., Maddison, L. A., Foster, B. A., and Greenberg, N. M. (2003) Prostate 55, 219-237
21. Huss, W. J., Gregory, C. W., and Smith, G. J. (2004) Prostate 60, 91-97
22. Jin, R. J., Wang, Y., Masumori, N., Ishii, K., Tsukamoto, T., Shappell, S. B., Hayward, S. W., Kasper, S., and Matusik, R. J. (2004) Cancer Res. 64, 5489-5495
23. Uchida, K., Masumori, N., Takahashi, A., Itoh, N., Kato, K., Matusik, R. J., and Tsukamoto, T. (2005) Prostate 62, 40-48
24. Huang, J., Yao, J. L., di Sant'agnese, P. A., Yang, Q., Bourne, P. A., and Na, Y. (2006) Prostate 66, 1399-1406
25. Huang, J., Yao, J. L., Zhang, L., Bourne, P. A., Quinn, A. M., di Sant'Agnese, P. A., and Reeder, J. E. (2005) Am. J. Pathol. 166, 1807-1815
26. Zelivianski, S., Verni, M., Moore, C., Kondrikov, D., Taylor, R., and Lin, M. F. (2001) Biochim. Biophys. Acta 1539, 28-43
27. Zhang, X. Q., Kondrikov, D., Yuan, T. C., Lin, F. F., Hansen, J., and Lin, M. F. (2003) Oncogene 22, 6704-6716
28. Wu, C., Zhang, L., Bourne, P. A., Reeder, J. E., di Sant'agnese, P. A., Yao, J. L., Na, Y., and Huang, J. (2006) Prostate 66, 1125-1135
29. Kim, J., Adam, R. M., and Freeman, M. R. (2002) Cancer Res. 62, 1549-1554
30. Lin, H. K., Hu, Y. C., Yang, L., Altuwaijri, S., Chen, Y. T., Kang, H. Y., and Chang, C. (2003) J. Biol. Chem. 278, 50902-50907
31. Stern, D. F. (2004) Clin. Cancer Res. 10, 6407-6410
32. Yoo, L. I., Liu, D. W., Le Vu, S., Bronson, R. T., Wu, H., and Yuan, J. (2006) Cancer Res. 66, 1929-1939
33. Majumder, P. K., and Sellers, W. R. (2005) Oncogene 24, 7465-7474
34. Steck, P. A., Pershouse, M. A., Jasser, S. A., Yung, W. K., Lin, H., Ligon, A. H., Langford, L. A., Baumgard, M. L., Hattier, T., Davis, T., Frye, C., Hu, R., Swedlund, B., Teng, D. H., and Tavtigian, S. V. (1997) Nat. Genet. 15, 356-362
35. Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H., and Parsons, R. (1997) Science 275, 1943-1947
36. Murillo, H., Huang, H., Schmidt, L. J., Smith, D. I., and Tindall, D. J. (2001) Endocrinology 142, 4795-4805
37. Li, L., Ittmann, M. M., Ayala, G., Tsai, M. J., Amato, R. J., Wheeler, T. M., Miles, B. J., Kadmon, D., and Thompson, T. C. (2005) Prostate Cancer Prostatic Dis. 8, 108-118
38. Luo, J., Manning, B. D., and Cantley, L. C. (2003) Cancer Cell 4, 257-262
39. Osaki, M., Oshimura, M., and Ito, H. (2004) Apoptosis 9, 667-676
40. Ayala, G., Thompson, T., Yang, G., Frolov, A., Li, R., Scardino, P., Ohori, M., Wheeler, T., and Harper, W. (2004) Clin. Cancer Res. 10, 6572-6578
41. Kreisberg, J. I., Malik, S. N., Prihoda, T. J., Bedolla, R. G., Troyer, D. A., Kreisberg, S., and Ghosh, P. M. (2004) Cancer Res. 64, 5232-5236
42. Majumder, P. K., Febbo, P. G., Bikoff, R., Berger, R., Xue, Q., McMahon, L. M., Manola, J., Brugarolas, J., McDonnell, T. J., Golub, T. R., Loda, M., Lane, H. A., and Sellers, W. R. (2004) Nat. Med. 10, 594-601
43. Xin, L., Teitell, M. A., Lawson, D. A., Kwon, A., Mellinghoff, I. K., and Witte, O. N. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 7789-7794
44. Lei, Q., Jiao, J., Xin, L., Chang, C. J., Wang, S., Gao, J., Gleave, M. E., Witte, O. N., Liu, X., and Wu, H. (2006) Cancer Cell 9, 367-378
45. Yoeli-Lerner, M., Yiu, G. K., Rabinovitz, I., Erhardt, P., Jauliac, S., and Toker, A. (2005) Mol. Cell 20, 539-550
46. Wyszomierski, S. L., and Yu, D. (2005) Cancer Cell 8, 437-439
47. Wright, M. E., Tsai, M. J., and Aebersold, R. (2003) Mol. Endocrinol. 17, 1726-1737
48. Yang, X., Chen, M. W., Terry, S., Vacherot, F., Bemis, D. L., Capodice, J., Kitajewski, J., de la Taille, A., Benson, M. C., Guo, Y., and Buttyan, R. (2006) Oncogene 25, 3436-3444
49. Yang, X., Chen, M. W., Terry, S., Vacherot, F., Chopin, D. K., Bemis, D. L., Kitajewski, J., Benson, M. C., Guo, Y., and Buttyan, R. (2005) Cancer Res. 65, 5263-5271
50. Adam, R. M., Kim, J., Lin, J., Orsola, A., Zhuang, L., Rice, D. C., and Freeman, M. R. (2002) Endocrinology 143, 4599-4608
51. Cinar, B., De Benedetti, A., and Freeman, M. R. (2005) Cancer Res. 65, 2547-2553
52. Zhuang, S., Yan, Y., Daubert, R. A., Han, J., and Schnellmann, R. (2006) Am. J. Physiol., in press