Dynamic changes of orexin A and leptin in obese children during body weight reduction

Physiological Research

Volumn 56, Issue 1, 2007, Pages 89-96

  Bronský, Jiří ^a   Nedvidkova J ^b   Zamrazilova H ^c   Pechova M ^a   Chada, M ^a,d   Kotaska K ^a   Nevoral, J ^a   Prusa R ^a  

^a UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

^b INSTITUTE OF ENDOCRINOLOGY   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Hypocretin 1; Leptin; Nutritional status; Obesity; Orexin A

Indexed keywords

LEPTIN; NEUROPEPTIDE; OREXINS; SIGNAL PEPTIDE; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ADOLESCENT; AGING; ARTICLE; BLOOD; BODY HEIGHT; BODY MASS; BODY WEIGHT; CHILD; FEMALE; HUMAN; MALE; METABOLISM; NUTRITIONAL STATUS; OBESITY; PHYSIOLOGY; RADIOIMMUNOASSAY; WEIGHT REDUCTION;

ADOLESCENT; AGING; BODY HEIGHT; BODY MASS INDEX; BODY WEIGHT; CHILD; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEPTIN; MALE; NEUROPEPTIDES; NUTRITIONAL STATUS; OBESITY; RADIOIMMUNOASSAY; WEIGHT LOSS;

EID: 33947520110     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. ADAM JA, MENHEERE PP, VAN DIELEN FM, SOETERS PB, BUURMAN WA, GREVE JW: Decreased plasma orexin-A levels in obese individuals. Int J Obes 26: 274-276, 2002.
2. ARCHER ZA, FINDLAY PA, RHIND SM, MERCER JG, ADAM CL: Orexin gene expression and regulation by photoperiod in the sheep hypothalamus. Regul Pept 104: 41-45, 2002.
3. ARIHARA Z, TAKAHASHI K, MURAKAMI O, TOTSUNE K, SONE M, SATOH F, ITO S, MOURI T: Immunoreactive orexin-A in human plasma. Peptides 22: 139-142, 2001.
4. BLUHER S, MANTZOROS CS: The role of leptin in regulating neuroendocrine function in humans. J Nutr 134: 2469S-2474S, 2004.
5. BRONSKÝ J, PRŮŠA R: Amylin fasting plasma levels are decreased in patients with osteoporosis. Osteoporos Int 15: 243-247, 2004.
6. CAI XJ, LIU XH, EVANS M, CLAPHAM JC, WILSON S, ARCH JR, MORRIS R, WILLIAMS G.: Orexins and feeding: special occasions or everyday occurrence? Regul Pept 104: 1-9, 2002.
7. CHANOINE JP, YEUNG LP, WONG AC, BIRMINGHAM CL: Immunoreactive ghrelin in human cord blood: relation to anthropometry, leptin, and growth hormone. J Pediatr Gastroenterol Nutr 35: 282-286, 2002.
8. CHEN C, XU R: The in vitro regulation of growth hormone secretion by orexins. Endocrine 22: 57-66, 2003.
9. DUBE MG, KALRA SP, KALRA PS: Food intake elicited by central administration of orexins/hypocretins: identification of hypothalamic sites of action. Brain Res 842: 473-477, 1999.
10. FUNAHASHI H, TAKENOYA F, GUAN JL, KAGEYAMA H, YADA T, SHIODA S: Hypothalamic neuronal networks and feeding-related peptides involved in the regulation of feeding. Anat Sci Int 78: 123-138, 2003a.
11. FUNAHASHI H, YAMADA S, KAGEYAMA H, TAKENOYA F, GUAN JL, SHIODA S: Co-existence of leptin- and orexin-receptors in feeding-regulating neurons in the hypothalamic arcuate nucleus - a triple labeling study. Peptides 24: 687-694, 2003b.
12. HAYNES AC, JACKSON B, OVEREND P, BUCKINGHAM RE, WILSON S, TADAYYON M, ARCH JR: Effects of single and chronic intracerebroventricular administration of the orexins on feeding in the rat. Peptides 20: 1099-1105, 1999.
13. HAYNES AC, JACKSON B, CHAPMAN H, TADAYYON M, JOHNS A, PORTER RA, ARCH JR: A selective orexin-1 receptor antagonist reduces food consumption in male and female rats. Regul Pept 96: 45-51, 2000.
14. HIGUCHI S, USUI A, MURASAKI M, MATSUSHITA S, NISHIOKA N, YOSHINO A, MATSUI T, MURAOKA H, ISHIZUKA Y, KANBA S, SAKURAI T: Plasma orexin-A is lower in patients with narcolepsy. Neurosci Lett 318: 61-64, 2002.
15. JOHREN O, NEIDERT SJ, KUMMER M, DENDORFER A, DOMINIAK P: Prepro-orexin and orexin receptor mRNAs are differentially expressed in peripheral tissues of male and female rats. Endocrinology 142: 3324-3331, 2001.
16. KANBAYASHI T, YANO T, ISHIGURO H, KAWANISHI K, CHIBA S, AIZAWA R, SAWAISHI Y, HIROTA K, NISHINO S, SHIMIZU T: Hypocretin-1 (orexin-A) levels in human lumbar CSF in different age groups: infants to elderly persons. Sleep 25: 337-339, 2002.
17. KARTERIS E, CHEN J, RANDEVA HS: Expression of human prepro-orexin and signaling characteristics of orexin receptors in the male reproductive system. J Clin Endocrinol Metab 89: 1957-1962, 2004.
18. KASTIN AJ, AKERSTROM V: Orexin A but not orexin B rapidly enters brain from blood by simple diffusion. J Pharmacol Exp Ther 298: 219-223, 1999.
19. KOK SW, OVEREEM S, VISSCHER TL, LAMMERS GJ, SEIDELL JC, PIJL H, MEINDERS AE: Hypocretin deficiency in narcoleptic humans is associated with abdominal obesity. Obes Res 11: 1147-1154, 2003.
20. KOMAKI G, MATSUMOTO Y, NISHIKATA H, KAWAI K, NOZAKI T, TAKII M, SOGAWA H, KUBO C: Orexin A and leptin change inversely in fasting non-obese subjects. Eur J Endocrinol 144: 645-651, 2001.
21. LHOTSKÁ L, BLÁHA P, VIGNEROVÁ J, ROTH Z, PROKOPEC M: 5th nation-wide anthropological survey 1991 in the Czech Republic: comparison with 1981 data. Cent Eur J Public Health 2: 95-99, 1994.
22. LOPEZ M, SEOANE LM, TOVAR S, NOGUEIRAS R, DIEGUEZ C, SENARIS R: Orexin-A regulates growth hormone-releasing hormone mRNA content in a nucleus-specific manner and somatostatin mRNA content in a growth hormone-dependent fashion in the rat hypothalamus. Eur J Neurosci 19: 2080-2088, 2004.
23. MATSUMURA T, NAKAYAMA M, NOMURA A, NAITO A, KAMAHARA K, KADONO K, INOUE M, HOMMA T, SEKIZAWA K: Age-related changes in plasma orexin-A concentrations. Exp Gerontol 37: 1127-1130, 2002.
24. MITSUMA T, HIROOKA Y, KAYAMA M, MORI Y, YOKOI Y, RHUE N, PING J, IZUMI M, IKAI R, ADACHI K, NOGIMORI T: Radioimmunoassay for orexin A. Life Sci 66: 897-904, 2000.
25. NISHINO S, REPLEY B, OVEREEM S, LAMMERS GJ, MIGNOT E: Hypocretin (orexin) deficiency in human narcolepsy. Lancet 355: 39-40, 2000.
26. O'RAHILLY S, FAROOQI IS: Recent advances in the genetics of severe childhood obesity. Arch Dis Child 83: 31-34, 2000.
27. OREL M, LICHNOVSKÁ R, GWOZDZIEWICZOVÁ S, ZLÁMALOVÁ N, KLEMENTA I, MERKUNOVÁ A, HŘEBÍ ČEK J: Gender differences in tumor necrosis factor alpha and leptin secretion from subcutaneous and visceral fat tissue. Physiol Res 53: 501-505, 2004.
28. SAKURAI T, AMEMIYA A, ISHII M, MATSUZAKI I, CHEMELLI RM, TANAKA H, WILLIAMS SC, RICHARSON JA, KOZLOWSKI GP, WILSON S, ARCH JR, BUCKINGHAM RE, HAYNES AC, CARR SA, ANNAN RS, MCNULTY DE, LIU WS, TERRETT JA, ELSHOURBAGY NA, BERGSMA DJ, YANAGISAWA M: Orexins and orexin receptors: a family of hypothalamic neuropeptides and G-protein coupled receptors that regulate feeding behavior. Cell 92: 573-585, 1998.
29. SEOANE LM, TOVAR SA, PEREZ D, MALLO F, LOPEZ M, SENARIS R, CASANUEVA FF, DIEGUEZ C: Orexin A suppresses in vivo GH secretion. Eur J Endocrinol 150: 731-736, 2004.
30. SMART D, HAYNES AC, WILLIAMS G, ARCH JR: Orexins and the treatment of obesity. Eur J Pharmacol 440: 199-212, 2002.
31. SWEET DC, LEVINE AS, BILLINGTON CJ, KOTZ CM: Feeding response to central orexins. Brain Res 821: 535-538, 1999.
32. TOMASIK PJ, SPODARYK M, SZTEFKO K: Plasma concentrations of orexins in children. Ann Nutr Metab 48: 215-220, 2004.
33. YAMADA H, OKUMURA T, MOTOMURA W, KOBAYASHI Y, KOHGO Y: Inhibition of food intake by central injection of anti-orexin antibody in fasted rats. Biochem Biophys Res Commun 267: 527-531, 2000.
34. YAMANAKA A, KUNII K, NAMBU T, TSUJINO N, SAKAI A, MATSUZAKI I, MIWA Y, GOTO K, SAKURAI T: Orexin-induced food intake involves neuropeptide Y pathway. Brain Res 859: 404-409, 2000.
35. YANAGISAWA M, BEUCKMANN CT: Orexins: from neuropeptides to energy homeostasis and sleep/wake regulation. J Mol Med 80: 329-342, 2002.