Double-mutant cycle scanning of the interaction of a peptide ligand and its G protein-coupled receptor

Biochemistry

Volumn 46, Issue 11, 2007, Pages 3476-3481

  Naider, Fred ^a   Becker, Jeffrey M ^b   Lee, Yong Hun ^b   Horovitz, Amnon ^c  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE-MUTANT CYCLE SCANNING; INTRAMOLECULAR INTERACTIONS; PROTEIN-COUPLED RECEPTORS; THERMODYNAMIC EVIDENCES;

AMINES; AMINO ACIDS; BINDING ENERGY; MOLECULAR DYNAMICS; MUTAGENS; THERMODYNAMIC PROPERTIES;

LIGANDS;

ALANINE; AMINO ACID; ASPARAGINE; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; MATING HORMONE ALPHA FACTOR; PEPTIDE; PROTEIN STE2P; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANALYTIC METHOD; ARTICLE; CARBOXY TERMINAL SEQUENCE; DOUBLE MUTANT CYCLE SCANNING ANALYSIS; ENERGY; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; THERMODYNAMICS; YEAST;

ALANINE; AMINO ACID SEQUENCE; BINDING, COMPETITIVE; LIGANDS; PEPTIDES; RECEPTORS, MATING FACTOR; SACCHAROMYCES CEREVISIAE PROTEINS; THERMODYNAMICS; TYROSINE;

EID: 33947434027     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi602415u     Document Type: Article

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