Aromatic residues at the extracellular ends of transmembrane domains 5 and 6 promote ligand activation of the G protein-coupled α-factor receptor

Biochemistry

Volumn 42, Issue 2, 2003, Pages 293-301

  Lin, Jennifer C ^a   Parrish, William ^a,b   Eilers, Markus ^a   Smith, Steven O ^a   Konopka, James B ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; BIOLOGICAL MEMBRANES; MUTAGENESIS; PROTEINS;

LIGANDS; TRANSMEMBRANE DOMAINS;

BIOCHEMISTRY;

G PROTEIN COUPLED RECEPTOR; MATING HORMONE ALPHA FACTOR;

ARTICLE; FUNGAL METABOLISM; FUNGUS GROWTH; LIGAND BINDING; NONHUMAN; PHYTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN DOMAIN; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CYSTEINE; EXTRACELLULAR SPACE; GTP-BINDING PROTEINS; LIGANDS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NOVOBIOCIN; PHENOTYPE; PHENYLALANINE; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; RECEPTORS, MATING FACTOR; RECEPTORS, PEPTIDE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS; TYROSINE;

FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0037457812     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026766o     Document Type: Article

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