Carrier-specificity of a phosphorylcholine-binding antibody requires the presence of the constant domains and is not dependent on the unique VH49 glycine or VH30 threonine residues

Journal of Immunological Methods

Volumn 321, Issue 1-2, 2007, Pages 152-163

  Tam, Frankie C H ^a   Ma, Chun Hung ^a   Leung, Danny T M ^a   Sutton, Brian ^b   Lim, Pak Leong ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Antigen; Fab; Immunoglobulin; Protein structure; scFv

Indexed keywords

GLYCINE; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; PHOSPHORYLCHOLINE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; THREONINE;

ANTIBODY COMBINING SITE; ANTIBODY SPECIFICITY; ANTIBODY STRUCTURE; ARTICLE; BACTERIUM; DISEASE CARRIER; HEAVY CHAIN; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, HELMINTH; ANTIBODY SPECIFICITY; ANTIGENS, HELMINTH; BINDING SITES, ANTIBODY; GLYCINE; HAPTENS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLCHOLINE; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; THREONINE; TRICHINELLA SPIRALIS;

EID: 33947327519     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2007.01.013     Document Type: Article

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