A Drosophila adenosine receptor activates cAMP and calcium signaling

Insect Biochemistry and Molecular Biology

Volumn 37, Issue 4, 2007, Pages 318-329

  Dolezelova, Eva ^a,b   Nothacker, Hans Peter ^b   Civelli, Olivier ^b   Bryant, Peter J ^b   Zurovec, Michal ^a  

^a UNIVERSITY OF SOUTH BOHEMIA   (Czech Republic)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adenosine deaminase; Adenosine deaminase growth factor; ADGF; Ca2+; CG9753; GPCR receptor

Indexed keywords

ADENOSINE; ADENOSINE RECEPTOR; CYCLIC AMP;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CHO CELL; CRICETULUS; DROSOPHILA; GENE EXPRESSION REGULATION; GENETICS; HAMSTER; HEMOLYMPH; INJECTION; METABOLISM; MOLECULAR GENETICS; PHENOTYPE; PHYSIOLOGY; SECOND MESSENGER; SEQUENCE ALIGNMENT;

ADENOSINE; AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; CYCLIC AMP; DROSOPHILA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMOLYMPH; INJECTIONS; MOLECULAR SEQUENCE DATA; PHENOTYPE; RECEPTORS, PURINERGIC P1; SECOND MESSENGER SYSTEMS; SEQUENCE ALIGNMENT;

CRICETULUS GRISEUS; HEXAPODA;

EID: 33947218943     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ibmb.2006.12.003     Document Type: Article

References (36)

1. Auchampach J.A., Jin J., Wan T.C., Caughey G.H., and Linden J. Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor. Mol. Pharmacol. 52 (1997) 846-860
2. Berne R.M. Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow. Am. J. Physiol. 204 (1963) 317-322
3. Brand A.H., and Perrimon N. Targeted gene expressions as a means of altering cell fates and generating dominant phenotypes. Development 118 (1993) 401-415
4. Brody T., and Cravchik A. Drosophila melanogaster G protein-coupled receptors. J. Cell Biol. 150 (2000) F83-F88
5. Costa F., and Biaggioni I. Role of nitric oxide in adenosine-induced vasodilation in humans. Hypertension 31 (1998) 1061-1064
6. Cunha R.A. Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: different roles, different sources and different receptors. Neurochem. Int. 38 (2001) 107-125
7. Dolezal T., Gazi M., Zurovec M., and Bryant P.J. Genetic analysis of the ADGF multigene family by homologous recombination and gene conversion in Drosophila. Genetics 165 (2003) 653-666
8. Dolezal T., Dolezelova E., Zurovec M., and Bryant P.J. The role of adenosine deaminase-related growth factor-A (ADGF-A) in Drosophila development. PLoS Biol. 3 (2005) e201
9. Dolezelova E., Zurovec M., Dolezal T., Simek P., and Bryant P.J. Emerging role of adenosine deaminases and extracellular adenosine in insects. Insect Biochem. Mol. Biol. 35 (2005) 381-389
10. Fredholm B.B., Arslan G., Halldner L., Kull B., Schulte G., and Wasserman W. Structure and function of adenosine receptors and their genes. Naunyn Schmiedebergs Arch. Pharmacol. 362 (2000) 364-374
11. Fredholm B.B., Irenius E., Kull B., and Schulte G. Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells. Biochem. Pharmacol. 61 (2001) 443-448
12. Fredholm B.B., Chen J.F., Masino S.A., and Vaugeois J.M. Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs. Annu. Rev. Pharmacol. Toxicol. 45 (2005) 385-412
13. Gao Z.G., Chen A., Barak D., Kim S.K., Muller C.E., and Jacobson K.A. Identification by site-directed mutagenesis of residues involved in ligand recognition and activation of the human A3 adenosine receptor. J. Biol. Chem. 277 (2002) 19056-19063
14. Hagberg H., Andersson P., Lacarewicz J., Jacobson I., Butcher S., and Sandberg M. Extracellular adenosine, inosine, hypoxanthine and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia. J. Neurochem. 49 (1987) 227-231
15. Hendricks J.C., Finn S.M., Panckeri K.A., Chavkin J., Williams J.A., Sehgal A., and Pack A.I. Rest in Drosophila is a sleep-like state. Neuron 25 (2000) 129-138
16. Jacobson K.A., and Gao Z.G. Adenosine receptors as therapeutic targets. Nat. Rev. Drug Discov. 5 (2006) 247-264
17. Kiger Jr. J.A., Natzle J.E., and Green M.M. Hemocytes are essential for wing maturation in Drosophila melanogaster. Proc. Nat. Acad. Sci. USA 98 (2001) 10190-10195
18. Kim S.K., Gao Z.G., Van Rompaey P., Gross A.S., Chen A., Van Calenbergh S., and Jacobson K.A. Modeling the adenosine receptors: comparison of the binding domains of A2A agonists and antagonists. J. Med. Chem. 46 (2003) 4847-4859
19. Kimura K.I., and Truman J.W. Postmetamorphic cell death in the nervous and muscular systems of Drosophila melanogaster. J. Neurosci. 10 (1990) 401-403
20. Kimura K.I., Kodama A., Hayasaka Y., and Ohta T. Activation of the cAMP/PKA signaling pathway is required for post-ecdysial cell death in wing epidermal cells of Drosophila melanogaster. Development 131 (2004) 1597-1606
21. Kobayashi S., Beitner-Johnson D., Conforti L., and Millhorn E. Chronic hypoxia reduces adenosine A2A receptor-mediated inhibition of calcium current in rat PC12 cells via down regulation of protein kinase A. J. Physiol. 512 (1998) 351-363
22. Londos C., Cooper D.M., and Wolff J. Subclasses of external adenosine receptors. Proc. Nat. Acad. Sci. USA 77 (1980) 2551-2554
23. Masino S.A., and Dulla C.G. Adenosine, glutamate and pH: interactions and implications. Neurol. Res. 27 (2005) 149-152
24. Murphree L.J., and Linden J. Adenosine receptors. In: Lennarz W., and Lane M. (Eds). Encyclopedia of Biological Chemistry vol. 1 (2004), Academic Press/Elsevier, Amsterdam 34-39
25. Newby A.C. Adenosine and the concept of "retaliatory metabolites". Trends Biochem. 9 (1984) 42-44
26. Nothacker H.P., Wang Z., Zhu Y., Reinscheid R.K., Lin S.H., and Civelli O. Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: discovery of a subtype selective agonist. Mol. Pharmacol. 58 (2000) 1601-1608
27. Nyce J.W. Insight into adenosine receptor function using antisense and gene-knockout approaches. Trends Pharmacol. Sci. 20 (1999) 79-83
28. Park S., and Lim J.K. A microinjection technique for ethanol-treated eggs and a mating scheme for detection of germ line transformants. Dros. Inf. Serv. 76 (1995) 197-199
29. Sankar N., Machado J., Abdulla P., Hilliker A.J., and Coe I.R. Comparative genomic analysis of equilibrative nucleoside transporters suggests conserved protein structure despite limited sequence identity. Nucleic Acids Res. 30 (2002) 4339-4350
30. Sitkovsky M., and Lukashev D. Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors. Nat. Rev. Immunol. 5 (2005) 712-721
31. Tuccinardi T., Ortore G., Manera C., Saccomanni G., and Martinelli A. Adenosine receptor modelling. A1/A2a selectivity. Eur. J. Med. Chem. 41 (2006) 321-329
32. van Calker D., Müller M., and Hamprecht B. Adenosine regulates via two different types of receptors the accumulation of cyclic AMP in cultured brain cells. J. Neurochem. 33 (1979) 999-1005
33. Vanden Broeck J.V. Insect G protein-coupled receptors and signal transduction. Arch. Insect Biochem. Physiol. 48 (2001) 1-12
34. 2+. Biochem. J. 374 (2003) 281-296
35. Zhao Z., Yaar R., Ladd D., Cataldo L.M., and Ravid K. Over-expression of A3 adenosine receptors in smooth, cardiac, and skeletal muscle is lethal to embryos. Microvasc. Res. 63 (2002) 61-69
36. Zurovec M., Dolezal T., Gazi M., Pavlova E., and Bryant P.J. Adenosine deaminase-related growth factors stimulate cell proliferation in Drosophila by depleting extracellular adenosine. Proc. Nat. Acad. Sci. USA 99 (2002) 4403-4408