Difluoromethyl analogs of the natural hormone 1α,25-dihydroxyvitamin D3: Design, synthesis, and preliminary biological evaluation

Journal of Steroid Biochemistry and Molecular Biology

Volumn 103, Issue 3-5, 2007, Pages 213-221

  Posner, Gary H ^a   Suh, Byung Chul ^a   Petersen, Kimberly S ^a   Dolan, Patrick ^a   Agoston, Elin S ^a   Kensler, Thomas W ^a   Koh, John T ^b   Peleg, Sara ^c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY OF DELAWARE   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

Fluorinated D analogs; Growth inhibition; Low calcemic; Protease digestion assay; VDR binding

Indexed keywords

CALCITRIOL; CALCIUM; VITAMIN D DERIVATIVE;

ARTICLE; CALCIUM URINE LEVEL; CHEMICAL STRUCTURE; EVALUATION; GROWTH INHIBITION; IN VIVO STUDY; KERATINOCYTE; NONHUMAN; SYNTHESIS; TRANSCRIPTION REGULATION;

ANIMALS; BIOLOGICAL PRODUCTS; CALCIUM; CELL PROLIFERATION; CELLS, CULTURED; DRUG DESIGN; FLUORINE; HORMONES; METHYLATION; MICE; MOLECULAR STRUCTURE; RATS; VITAMIN D;

MURINAE;

EID: 33947173748     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2006.12.024     Document Type: Article

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