Human CYP11A1 promoter drives Cre recombinase expression in the brain in addition to adrenals and gonads

Genesis (United States)

Volumn 45, Issue 2, 2007, Pages 59-65

  Wu, Hsu Shui ^a   Lin, Hui Ting ^a   Wang, Chi Kuang Leo ^b   Chiang, Yen Feng ^a   Chu, Hsueh Ping ^b   Hu, Meng Chun ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

Author keywords

Adrenal; Cre; CYP11A1; Diencephalon; Gonad; Hippocampus; Midbrain; VMHDM

Indexed keywords

CRE RECOMBINASE; CYTOCHROME P450; CYTOCHROME P450 CYP11A1; UNCLASSIFIED DRUG;

ADRENAL CORTEX; ADRENAL GLAND; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN DEVELOPMENT; CATALYSIS; DIENCEPHALON; EMBRYO; ENZYME ACTIVITY; GENE INACTIVATION; GENETIC CODE; GENETIC TRANSCRIPTION; GONAD; HIPPOCAMPUS; MESENCEPHALON; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REGULATOR GENE; STEROIDOGENESIS; TISSUE SPECIFICITY;

MUS;

EID: 33947135886     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.20266     Document Type: Article

References (30)

1. Branda CS, Dymecki SM. 2004. Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice. Dev Cell 6:7-28.
2. Chou SJ, Lai KN, Chung B. 1996. Characterization of the upstream sequence of the human CYP11A1 gene for cell type-specific expression. J Biol Chem 271:22125-22129.
3. Chung JH, Whiteley M, Felsenfeld G. 1993. A 5′ element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila. Cell 74:505-514.
4. Deacon CF, Mosley W, Jones IC. 1986. The X zone of the mouse adrenal cortex of the Swiss albino strain. Gen Comp Endocrinol 61: 87-99.
5. Durkee TJ, McLean MP, Hales DB, Payne AH, Waterman MR, Khan I, Gibori G. 1992. P450(17 α) and P450SCC gene expression and regulation in the rat placenta. Endocrinology 130:1309-1317.
6. Furukawa A, Miyatake A, Ohnishi T, Ichikawa Y. 1998. Steroidogenic acute regulatory protein (StAR) transcripts constitutively expressed in the adult rat central nervous system: Colocalization of StAR, cytochrome P-450SCC (CYP XIA1), and 3β-hydroxysteroid dehydrogenase in the rat brain. J Neurochem 71:2231-2238.
7. Guo IC, Hu MC, Chung BC. 2003. Transcriptional regulation of CYP11A1. J Biomed Sci 10:593-598.
8. Guo IC, Tsai HM, Chung BC. 1994. Actions of two different cAMP-responsive sequences and an enhancer of the human CYP11A1 (P450scc) gene in adrenal Y1 and placental JEG-3 cells. J Biol Chem 269:6362-6369.
9. Hu MC, Chou SJ, Huang YY, Hsu NC, Li H, Chung BC. 1999. Tissue-specific, hormonal, and developmental regulation of SCC-LacZ expression in transgenic mice leads to adrenocortical zone characterization. Endocrinology 140:5609-5618.
10. Hum DW, Staels B, Black SM, Miller WL. 1993. Basal transcriptional activity and cyclic adenosine 3′,5′-monophosphate responsiveness of the human cytochrome P450scc promoter transfected into MA-10 Leydig cells. Endocrinology 132:546-552.
11. Inoue H, Watanabe N, Higashi Y, Fujii-Kuriyama Y. 1991. Structures of regulatory regions in the human cytochrome P-450scc (desmolase) gene. Eur J Biochem 195:563-569.
12. Keeney DS, Ikeda Y, Waterman MR, Parker KL. 1995. Cholesterol side-chain cleavage cytochrome P450 gene expression in the primitive gut of the mouse embryo does not require steroidogenic factor 1. Mol Endocrinol 9:1091-1098.
13. Kimoto T, Tsurugizawa T, Ohta Y, Makino J, Tamura H, Hojo Y, Takata N, Kawato S. 2001. Neurosteroid synthesis by cytochrome p450-containing systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate and calcium-dependent synthesis. Endocrinology 142:3578-3589.
14. Kwan KM. 2002. Conditional alleles in mice: Practical considerations for tissue-specific knockouts. Genesis 32:49-62.
15. Luo X, Ikeda Y, Parker KL. 1994. A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. Cell 77:481-490.
16. Mellon SH, Deschepper CF. 1993. Neurosteroid biosynthesis: Genes for adrenal steroidogenic enzymes are expressed in the brain. Brain Res 629:283-292.
17. Mellon SH, Miller WL, Bair SR, Moore CC, Vigne JL, Weiner RI. 1994. Steroidogenic adrenocortical cell lines produced by genetically targeted tumorigenesis in transgenic mice. Mol Endocrinol 8:97-108.
18. Metzger D, Feil R. 1999. Engineering the mouse genome by site-specific recombination. Curr Opin Biotechnol 10:470-476.
19. Miller WL. 1988. Molecular biology of steroid hormone synthesis. Endocr Rev 9:295-318.
20. Morohashi K. 1999. Gonadal and extragonadal functions of Ad4BP/SF-1: Developmental aspects. Trends Endocrinol Metab 10:169-173.
21. Parker KL, Schimmer BP. 1997. Steroidogenic factor 1: A key determinant of endocrine development and function. Endocr Rev 18:361-377.
22. Recillas-Targa F, Valadez-Graham V, Farrell CM. 2004. Prospects and implications of using chromatin insulators in gene therapy and transgenesis. Bioessays 26:796-807.
23. Sanne JL, Krueger KE. 1995. Expression of cytochrome P450 side-chain cleavage enzyme and 3 β-hydroxysteroid dehydrogenase in the rat central nervous system: A study by polymerase chain reaction and in situ hybridization. J Neurochem 65:528-536.
24. Shimshek DR, Kim J, Hubner MR, Spergel DJ, Buchholz F, Casanova E, Stewart AF, Seeburg PH, Sprengel R. 2002. Codon-improved Cre recombinase (iCre) expression in the mouse. Genesis 32:19-26.
25. Shinoda K, Lei H, Yoshii H, Nomura M, Nagano M, Shiba H, Sasaki H, Osawa Y, Ninomiya Y, Niwa O, Morohashi KI, Li E. 1995. Developmental defects of the ventromedial hypothalamic nucleus and pituitary gonadotroph in the Ftz-F1 disrupted mice. Dev Dyn 204:22-29.
26. Silvestre JS, Robert V, Heymes C, Aupetit-Faisant B, Mouas C, Moalic JM, Swynghedauw B, Delcayre C. 1998. Myocardial production of aldosterone and corticosterone in the rat. Physiological regulation. J Biol Chem 273:4883-4891.
27. Soriano P. 1999. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21:70-71.
28. Ukena K, Usui M, Kohchi C, Tsutsui K. 1998. Cytochrome P450 side-chain cleavage enzyme in the cerebellar Purkinje neuron and its neonatal change in rats. Endocrinology 139:137-147.
29. Watzka M, Bidlingmaier F, Schramm J, Klingmuller D, Stoffel-Wagner B. 1999. Sex- and age-specific differences in human brain CYP11A1 mRNA expression. J Neuroendocrinol 11:901-905.
30. Zhang P, Rodriguez H, Mellon SH. 1995. Transcriptional regulation of P450scc gene expression in neural and steroidogenic cells: Implications for regulation of neurosteroidogenesis. Mol Endocrinol 9:1571-1582.