Gonadal and extragonadal functions of Ad4BP/SF-1: Developmental aspects

Trends in Endocrinology and Metabolism

Volumn 10, Issue 5, 1999, Pages 169-173

  Morohashi, Ken Ichirou ^a  

^a National Institute for Basic Biology   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

STEROIDOGENIC FACTOR 1; TRANSCRIPTION FACTOR;

GENE DISRUPTION; GENE EXPRESSION; GENETIC TRANSCRIPTION; GONAD DEVELOPMENT; GONAD FUNCTION; ONTOGENY; PRIORITY JOURNAL; REVIEW; TISSUE DIFFERENTIATION;

EID: 0033025545     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-2760(98)00142-8     Document Type: Review

References (38)

1. Miller W.L. Molecular biology of steroid hormone synthesis. Endocr. Rev. 9:1988;295-318.
2. Waterman M.R. Biochemical diversity of cAMP-dependent transcription of steroid hydroxylase genes in the adrenal cortex. J. Biol. Chem. 269:1994;27783-27786.
3. Morohashi K., Omura T. Ad4BP/SF-1, a transcription factor essential for the transcription of steroidogenic cytochrome P450 genes and for the establishment of reproductive function. FASEB J. 10:1996;1569-1577.
4. Parker K.L., Schimmer B.P. Steroidogenic factor 1: a key determinant of endocrine development and function. Endocr. Rev. 18:1997;361-377.
5. Lala D.S., Rice D.A., Parker K.L. Steroidogenic factor I, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor I. Mol. Endocrinol. 6:1992;1249-1258.
6. Honda S., Morohashi K., Nomura M., Takeya H., Kitajima M., Omura T. Ad4BP regulating steroidogenic P-450 gene is a member of the steroid hormone receptor superfamily. J. Biol. Chem. 268:1993;7494-7502.
7. Morohashi K.et al. Functional difference between Ad4BP and ELP, and their distributions in the steroidogenic tissues. Mol. Endocrinol. 8:1994;643-653.
8. Ikeda Y., Lala D.S., Luo X., Kim E., Moison M-P., Parker K.L. Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression. Mol. Endocrinol. 7:1993;852-860.
9. Ingraham H.A.et al. The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis. Genes Dev. 8:1994;2302-2312.
10. Shinoda K.et al. Developmental defects of the ventromedial hypothalamic nucleus and pituitary gonadotroph in ftz-F1 disrupted mice. Dev. Dyn. 204:1995;22-29.
11. Ninomiya Y., Okada M., Kotomura N., Suzuki K., Tsukiyama T., Niwa O. Genomic organization and isoforms of the mouse ELP gene. J. Biochem. 118:1995;380-389.
12. Ramayya M.S., Zhou J., Kino T., Segars J.H., Bondy C.A., Chrousos G.P. Steroidogenic factor 1 messenger ribonucleic acid expression in steroidogenic and nonsteroidogenic human tissues: northern blot and in situ hybridization studies. J. Clin. Endocrinol. Metab. 82:1997;1799-1806.
13. Morohashi K.et al. Structural and functional abnormalities in the spleen of the mFtz-F1 gene disrupted mouse. Blood. 93:1999;1586-1594.
14. Kalra S.P., Kalra P.S. Regulation of gonadotropin secretion. Imura H. The Pituitary Gland. 1994;285-307 Raven Press.
15. Ikeda Y., Luo X., Abbud R., Nilson J.H., Parker K.L. The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus. Mol. Endocrinol. 9:1995;478-486.
16. McEwen B.S. Steroid hormones: effect on brain development and function. Horm. Res. 37(Suppl.):1992;1-10.
17. Weiss L. The Spleen. 1988;516-538 Urban and Schwarzenberg.
18. Burke J.S., Simon G.T. Electron microscopy of the spleen. Am. J. Pathol. 58:1970;127-155.
19. Suzuki T., Tabata Y., Sasaki H. Fine architecture of the splenic terminal vascular bed as revealed by arterial and venous pressure-loading perfusion fixation. J. Electron Microsc. Tech. 12:1989;132-145.
20. Luo X., Ikeda Y., Parker K.L. A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. Cell. 77:1994;481-490.
21. Sadovsky Y.et al. Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids. Proc. Natl. Acad. Sci. U. S. A. 92:1995;10939-10943.
22. Hatano O.et al. Sex-dependent expression of a transcription factor, Ad4BP, regulating steroidogenic P-450 genes in the gonads during prenatal and postnatal rat development. Development. 120:1994;2787-2797.
23. Ikeda Y., Shen W-H., Ingraham H.A., Parker K.L. Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases. Mol. Endocrinol. 8:1994;654-662.
24. Hatano O., Takakusu A., Nomura M., Morohashi K. Identical origin of adrenal cortex and gonad revealed by expression profiles of Ad4BP/SF-1. Genes Cells. 1:1996;663-671.
25. Morohashi K. The ontogenesis of the steroidogenic tissues. Genes Cells. 2:1997;95-106.
26. Ikeda Y.et al. Steroidogenic factor 1 and Dax-1 colocalize in multiple cell lineages: potential links in endocrine development. Mol. Endocrinol. 10:1996;1261-1272.
27. 4 isomerase promoter by the transcription factor adrenal 4-binding protein/steroidogenic factor-1: synergistic activation by phorbol ester. J. Biol. Chem. 272:1995;7960-7967.
28. Caron K.M., Ikeda Y., Soo S-C., Stocco D.M., Parker K.L., Clark B.J. Characterization of the promoter region of the mouse gene encoding the steroidogenic acute regulatory protein. Mol. Endocrinol. 11:1997;138-147.
29. Sugawara T., Kiriakidou M., McAllister J.M., Kallen C.B., Strauss J.F. III Multiple steroidogenic factor 1 binding elements in the human steroidogenic acute regulatory protein gene 5′-flanking region are required for maximal promoter activity and cyclic AMP responsiveness. Biochemistry. 36:1997;7249-7255.
30. Giuili G., Shen W-H., Ingraham H.A. The nuclear receptor SF-1 mediates sexually dimorphic expression of Müllerian inhibiting substance, in vivo. Development. 124:1997;1799-1807.
31. Zimmermann S., Schwärzler A., Buth S., Engel W., Adham I.M. Transcription of Leydig insulin-like gene is mediated by steroidogenic factor-1. Mol. Endocrinol. 12:1998;706-713.
32. Cammas F.M., Pullinger G.D., Barker S., Clark A.J.L. The mouse adrenocorticotropin receptor gene: cloning and characterization of its promoter and evidence for a role for the orphan nuclear receptor steroidogenic factor 1. Mol. Endocrinol. 11:1997;867-876.
33. Nachtigal M.W., Hirokawa Y., Enyeart-VanHouten D.L., Flanagan J.N., Hammer G.D., Ingraham H.A. Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression. Cell. 93:1998;445-454.
34. De Santa Barbara P.et al. Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene. Mol. Cell. Biol. 18:1998;6653-6665.
35. Morohashi K., Zanger U.M., Honda S., Hara M., Waterman M.R., Omura T. Activation of CYP11A and CYP11B gene promoters by the steroidogenic cell-specific transcription factor, Ad4BP. Mol. Endocrinol. 7:1993;1196-1204.
36. Lee S.L.et al. Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1). Science. 273:1996;1219-1221.
37. Liu Z., Simpson E.R. Steroidogenic factor 1 (SF-1) and SP1 are required for regulation of bovine CYP11A gene expression in bovine luteal cells and adrenal Y1 cells. Mol. Endocrinol. 11:1997;127-137.
38. Tremblay J.J., Lanctot C., Drouin J. The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit1 and is an upstream regulator of the Lim-homeodomain gene Lim3/Lhx3. Mol. Endocrinol. 12:1998;428-441.