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Volumn 14, Issue 11, 2006, Pages 381-387

Angiotensin II receptor antagonists (AT1 blockers, ARBs, sartans): Similarities and differences

Author keywords

Angiotensin II receptor antagonists; AT1 receptors; Insulin sensitisation; Renin angiotensin system

Indexed keywords

2 BUTYL 4 CHLORO 1 (2 CHLOROBENZYL) 5 IMIDAZOLEACETIC ACID; 2 BUTYL 4 CHLORO 1 (2 NITROBENZYL) 5 IMIDAZOLEACETIC ACID; 2 BUTYL 4 CHLORO 1 [[2' (1H TETRAZOL 5 YL) 4 BIPHENYLYL]METHYL] 5 IMIDAZOLECARBOXYLIC ACID; AMLODIPINE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN I; ANGIOTENSIN II; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CANDESARTAN; CANDESARTAN HEXETIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ENALAPRIL; EPROSARTAN; GLITAZONE DERIVATIVE; INSULIN; IRBESARTAN; KINZAL; LOSARTAN; OLMESARTAN; PIOGLITAZONE; PRODRUG; RENIN INHIBITOR; ROSIGLITAZONE; SARALASIN; TELMISARTAN; UNCLASSIFIED DRUG; VALSARTAN;

EID: 33947130913     PISSN: 15685888     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (16)

References (46)
  • 1
    • 0030594604 scopus 로고    scopus 로고
    • Angiotensin receptors and their antagonists
    • Goodfriend TL, Elliot ME, Can KJ. Angiotensin receptors and their antagonists. N Engl J Med 1996;334:1649-54.
    • (1996) N Engl J Med , vol.334 , pp. 1649-1654
    • Goodfriend, T.L.1    Elliot, M.E.2    Can, K.J.3
  • 2
    • 0027076082 scopus 로고
    • Renin-angiotensin system: A dual tissue and hormonal system for cardiovascular control
    • Johnston CI. Renin-angiotensin system: a dual tissue and hormonal system for cardiovascular control. J Hypertens 1992;10:S13-26.
    • (1992) J Hypertens , vol.10
    • Johnston, C.I.1
  • 3
    • 0025010150 scopus 로고
    • The angiotensin II receptor and the actions of angiotensin II
    • Peach MJ, Dostal DE. The angiotensin II receptor and the actions of angiotensin II. J Cardiovasc Pharmacol 1990;16:S25-30.
    • (1990) J Cardiovasc Pharmacol , vol.16
    • Peach, M.J.1    Dostal, D.E.2
  • 4
    • 14844363404 scopus 로고    scopus 로고
    • Gradman AH, Schmeider PR, Lins RL, Nussberger J, Chiang Y, Bedigian MP. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 2005;111:1012-8.
    • Gradman AH, Schmeider PR, Lins RL, Nussberger J, Chiang Y, Bedigian MP. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 2005;111:1012-8.
  • 5
    • 0018452442 scopus 로고
    • Outpatient experience with saralasin
    • Streeten DHP. Outpatient experience with saralasin. Kidney Int 1979;159(Suppl 9):44-52.
    • (1979) Kidney Int , vol.159 , Issue.SUPPL. 9 , pp. 44-52
    • Streeten, D.H.P.1
  • 6
    • 0027208070 scopus 로고
    • Angiotensin II receptors and angiotensin II receptor antagonists
    • Timmermans PBMWM, Wong PC, Chin AT, et al. Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev 1993;45:205-51.
    • (1993) Pharmacol Rev , vol.45 , pp. 205-251
    • PBMWM, T.1    Wong, P.C.2    Chin, A.T.3
  • 7
    • 0031427248 scopus 로고    scopus 로고
    • Rationale and pharmacology of angiotensin II receptor antagonists: Current status and future issues
    • Johnston CI, Naitoh M, Burrell LM. Rationale and pharmacology of angiotensin II receptor antagonists: current status and future issues. J Hypertens 1997;15(Suppl 8):3-6.
    • (1997) J Hypertens , vol.15 , Issue.SUPPL. 8 , pp. 3-6
    • Johnston, C.I.1    Naitoh, M.2    Burrell, L.M.3
  • 8
    • 0031720741 scopus 로고    scopus 로고
    • Angiotensin II receptor blockade and end-organ protection: Pharmacological rationale and evidence
    • Unger T, Culman J, Gohlke P. Angiotensin II receptor blockade and end-organ protection: pharmacological rationale and evidence. J Hypertens 1998;16(Suppl 17):3-9.
    • (1998) J Hypertens , vol.16 , Issue.SUPPL. 17 , pp. 3-9
    • Unger, T.1    Culman, J.2    Gohlke, P.3
  • 9
    • 0023807715 scopus 로고
    • Non-peptide angiotensin II receptor antagonists. I. Pharmacological characterization of 2-n-butyl-4-chloro-1-2(2- chlorobenzyl)imidazole-5-acetic acid sodium salt (S8307)
    • Wong PC, Chui AT, Price WA, et al. Non-peptide angiotensin II receptor antagonists. I. Pharmacological characterization of 2-n-butyl-4-chloro-1-2(2- chlorobenzyl)imidazole-5-acetic acid sodium salt (S8307). J Pharmacol Exp Ther 1988;247:1-10.
    • (1988) J Pharmacol Exp Ther , vol.247 , pp. 1-10
    • Wong, P.C.1    Chui, A.T.2    Price, W.A.3
  • 11
    • 0031418447 scopus 로고    scopus 로고
    • Preclinical pharmacology of angiotensin II receptor antagonists
    • Johnston CI, Risvanis J. Preclinical pharmacology of angiotensin II receptor antagonists. Am J Hypertens 1997;10:S306-10.
    • (1997) Am J Hypertens , vol.10
    • Johnston, C.I.1    Risvanis, J.2
  • 12
    • 0030480760 scopus 로고    scopus 로고
    • Angiotensin receptors
    • Unger T, Chung O, Csikos T, et al. Angiotensin receptors. J Hypertens 1996;14(Suppl):95-103.
    • (1996) J Hypertens , vol.14 , Issue.SUPPL. , pp. 95-103
    • Unger, T.1    Chung, O.2    Csikos, T.3
  • 13
    • 0029619525 scopus 로고    scopus 로고
    • 2-receptors. Eur J Pharmacol 1995;294:439-50.
    • 2-receptors. Eur J Pharmacol 1995;294:439-50.
  • 15
    • 0027972636 scopus 로고
    • A non-competitive type of angiotensin II receptor antagonism by losartan in renal artery preparations
    • Zhang J, Pfaffendorf M, Zhang JS, van Zwieten PA. A non-competitive type of angiotensin II receptor antagonism by losartan in renal artery preparations. Eur J Pharmacol 1994;252:337-40.
    • (1994) Eur J Pharmacol , vol.252 , pp. 337-340
    • Zhang, J.1    Pfaffendorf, M.2    Zhang, J.S.3    van Zwieten, P.A.4
  • 16
    • 0030296402 scopus 로고    scopus 로고
    • Effects of losartan on vasoconstrictor responses to angiotensin II in the human forearm vascular bed of healthy volunteers
    • Baan J, Chang PC, Vermeij P, Pfaffendorf M, van Zwieten PA. Effects of losartan on vasoconstrictor responses to angiotensin II in the human forearm vascular bed of healthy volunteers. Cardiovasc Res 1996;32:973-9.
    • (1996) Cardiovasc Res , vol.32 , pp. 973-979
    • Baan, J.1    Chang, P.C.2    Vermeij, P.3    Pfaffendorf, M.4    van Zwieten, P.A.5
  • 17
    • 0027490969 scopus 로고    scopus 로고
    • 1-subtype angiotensin II receptor antagonist. J Pharmacol Exp Ther 1993; 265:826-34.
    • 1-subtype angiotensin II receptor antagonist. J Pharmacol Exp Ther 1993; 265:826-34.
  • 18
    • 0027431141 scopus 로고
    • Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[2-(1H tetrazol-5-yl)biphenyl-4-yl]-methyl]-1H benzimidazole-7-carboxylic acid (CV 11974), and its prodrug, (±)-1-(cyclohexyloxycarbonyloxy]-ethyl-2-ethoxy- 1-[[2-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl]-1H benzimidazole-7 carboxylate (TCY-116)
    • Shibouta Y, Inada Y, Ogima, et al. Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[2-(1H tetrazol-5-yl)biphenyl-4-yl]-methyl]-1H benzimidazole-7-carboxylic acid (CV 11974), and its prodrug, (±)-1-(cyclohexyloxycarbonyloxy]-ethyl-2-ethoxy- 1-[[2-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl]-1H benzimidazole-7 carboxylate (TCY-116). J Pharmacol Exp Ther 1993;266:114-20.
    • (1993) J Pharmacol Exp Ther , vol.266 , pp. 114-120
    • Shibouta, Y.1    Inada, Y.2    Ogima3
  • 19
    • 0035852724 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor blockers
    • Burnier M. Angiotensin II type 1 receptor blockers. Circulation 2001;103:904-912.
    • (2001) Circulation , vol.103 , pp. 904-912
    • Burnier, M.1
  • 20
    • 0031948041 scopus 로고    scopus 로고
    • Comparative pharmacology of the angiotensin II receptor antagonists
    • Dzielak DJ. Comparative pharmacology of the angiotensin II receptor antagonists. Exp Opin Invest Drugs 1998;7:741-51.
    • (1998) Exp Opin Invest Drugs , vol.7 , pp. 741-751
    • Dzielak, D.J.1
  • 21
    • 0028829712 scopus 로고
    • Angioedema induced by the angiotensin II blocker losartan
    • Acker CG, Greenberg A. Angioedema induced by the angiotensin II blocker losartan. N Engl J Med 1995;333:1572.
    • (1995) N Engl J Med , vol.333 , pp. 1572
    • Acker, C.G.1    Greenberg, A.2
  • 22
    • 0037160968 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): A randomized trial against atenolol
    • Dahlöf B, Devereux RB, Kjeldsen SE, et al. Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomized trial against atenolol. Lancet 2002;359:995-1003.
    • (2002) Lancet , vol.359 , pp. 995-1003
    • Dahlöf, B.1    Devereux, R.B.2    Kjeldsen, S.E.3
  • 23
    • 0035922441 scopus 로고    scopus 로고
    • RENAAL-study investigations. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • Brenner BM, Cooper ME, de Zeeuw D, et al. RENAAL-study investigations. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001;345:861-9.
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    de Zeeuw, D.3
  • 24
    • 0030902115 scopus 로고    scopus 로고
    • On behalf of the ELITE Study Investigators. Randomized trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan In The Elderly Study, ELITE)
    • Pitt B, Segal R, Matinez FA, et al. On behalf of the ELITE Study Investigators. Randomized trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan In The Elderly Study, ELITE). Lancet 1997;349:747-52.
    • (1997) Lancet , vol.349 , pp. 747-752
    • Pitt, B.1    Segal, R.2    Matinez, F.A.3
  • 25
    • 0037534905 scopus 로고    scopus 로고
    • The study on cognition and prognosis in the elderly (SCOPE): Principal results of a randomized double blind intervention trial
    • Lithell H, Hansson L, Skoog I, et al. The study on cognition and prognosis in the elderly (SCOPE): principal results of a randomized double blind intervention trial. J Hypertens 2003;21:875-86.
    • (2003) J Hypertens , vol.21 , pp. 875-886
    • Lithell, H.1    Hansson, L.2    Skoog, I.3
  • 26
    • 0041328910 scopus 로고    scopus 로고
    • Candesartan and heart failure: The allure of CHARM
    • White HD. Candesartan and heart failure: the allure of CHARM. Lancet 2003;362:754-5.
    • (2003) Lancet , vol.362 , pp. 754-755
    • White, H.D.1
  • 27
    • 0031882729 scopus 로고    scopus 로고
    • The anohypertensive effect and tolerability of candesartan cilexetil, a new generation angiotensin II antagonist, in comparison with losartan
    • Andersson OK, Neldman S. The anohypertensive effect and tolerability of candesartan cilexetil, a new generation angiotensin II antagonist, in comparison with losartan. Blood Pressure 1998;7:53-9.
    • (1998) Blood Pressure , vol.7 , pp. 53-59
    • Andersson, O.K.1    Neldman, S.2
  • 28
    • 33947099409 scopus 로고    scopus 로고
    • 1-receptor blocker. J Hum Hypertens 1997;11(Suppl 2):1-95.
    • 1-receptor blocker. J Hum Hypertens 1997;11(Suppl 2):1-95.
  • 31
    • 0035922444 scopus 로고    scopus 로고
    • The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
    • Parring HH, Lehnert H, Brochner-Mortensen J, et al. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 2001;345:870-8.
    • (2001) N Engl J Med , vol.345 , pp. 870-878
    • Parring, H.H.1    Lehnert, H.2    Brochner-Mortensen, J.3
  • 32
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effects of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis EJ, Huusicker LG, Clarke WR, et al. Renoprotective effects of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001;345:851-60.
    • (2001) N Engl J Med , vol.345 , pp. 851-860
    • Lewis, E.J.1    Huusicker, L.G.2    Clarke, W.R.3
  • 33
    • 0030694110 scopus 로고    scopus 로고
    • Irbesartan. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in the management of hypertension
    • Gillis JC, Markham A. Irbesartan. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in the management of hypertension. Drugs 1997;54:885-902.
    • (1997) Drugs , vol.54 , pp. 885-902
    • Gillis, J.C.1    Markham, A.2
  • 34
    • 0031427249 scopus 로고    scopus 로고
    • Clinical overview of irbesartan: Expanding the therapeutic window in hypertension
    • Man in 't Veld AJ. Clinical overview of irbesartan: expanding the therapeutic window in hypertension. J Hypertension 1997;15(Suppl 7):27-33.
    • (1997) J Hypertension , vol.15 , Issue.SUPPL. 7 , pp. 27-33
    • Man in 't Veld, A.J.1
  • 35
    • 85087246477 scopus 로고    scopus 로고
    • Clinical efficacy of olmesartan medoxomil
    • Brunner HR, Laers P. Clinical efficacy of olmesartan medoxomil. J Hyertens 2003;21(Suppl 2):543-6.
    • (2003) J Hyertens , vol.21 , Issue.SUPPL. 2 , pp. 543-546
    • Brunner, H.R.1    Laers, P.2
  • 36
    • 10844222742 scopus 로고    scopus 로고
    • The role of olmesartan medoxomil in the management of hypertension
    • Unger T, McInnes GT, Neutel JM, Böhm M. The role of olmesartan medoxomil in the management of hypertension. Drugs 2004;64:2731-9.
    • (2004) Drugs , vol.64 , pp. 2731-2739
    • Unger, T.1    McInnes, G.T.2    Neutel, J.M.3    Böhm, M.4
  • 37
    • 7444237666 scopus 로고    scopus 로고
    • Angiotensin receptor blockade versus converting enzyme inhibition in type 2 diabetes and nephropathy
    • Barnett AH, Bain SC, Bouter P, et al. Angiotensin receptor blockade versus converting enzyme inhibition in type 2 diabetes and nephropathy. N Engl J Med 2004;351:1952-61.
    • (2004) N Engl J Med , vol.351 , pp. 1952-1961
    • Barnett, A.H.1    Bain, S.C.2    Bouter, P.3
  • 38
    • 1542547460 scopus 로고    scopus 로고
    • Identification of telmisartan as an unique angiotensin II receptor antagonist with selective PPAR-γ modulating activity
    • Benson SC, Perchadsingh HA, Ho CI, et al. Identification of telmisartan as an unique angiotensin II receptor antagonist with selective PPAR-γ modulating activity. Hypertension 2004;43:993-1002.
    • (2004) Hypertension , vol.43 , pp. 993-1002
    • Benson, S.C.1    Perchadsingh, H.A.2    Ho, C.I.3
  • 39
    • 2442451618 scopus 로고    scopus 로고
    • Angiotensin type I receptor include peroxizome proliferator activated receptor-γ activity
    • Schupp M, Janke J, Clasen R, Unger T, Kintschen U. Angiotensin type I receptor include peroxizome proliferator activated receptor-γ activity. Circulation 2004;109:2054-7.
    • (2004) Circulation , vol.109 , pp. 2054-2057
    • Schupp, M.1    Janke, J.2    Clasen, R.3    Unger, T.4    Kintschen, U.5
  • 40
    • 14944381514 scopus 로고    scopus 로고
    • Current status of angiotensin receptor blockers for the treatment of cardiovascular diseases: Focus on telmisartan
    • Chrysant SG, Chrysant GS, Desai A. Current status of angiotensin receptor blockers for the treatment of cardiovascular diseases: focus on telmisartan. J Hum Hypertens 2005;19:173-83.
    • (2005) J Hum Hypertens , vol.19 , pp. 173-183
    • Chrysant, S.G.1    Chrysant, G.S.2    Desai, A.3
  • 41
    • 2942635317 scopus 로고    scopus 로고
    • VALUE Trial Group. Outcomes in hypertensive patients at high cardiovascular risk treated with regimes based on valsartan or amlodipine: The VALUE randomised trial
    • Julius S, Kjeldsen SE, Weber M, et al. VALUE Trial Group. Outcomes in hypertensive patients at high cardiovascular risk treated with regimes based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004;363:2022-31.
    • (2004) Lancet , vol.363 , pp. 2022-2031
    • Julius, S.1    Kjeldsen, S.E.2    Weber, M.3
  • 42
    • 0242490542 scopus 로고    scopus 로고
    • Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both
    • Pfeffer MA, Mc Murray JJ, Velasquez EJ, et al. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 2003;349:1893-906.
    • (2003) N Engl J Med , vol.349 , pp. 1893-1906
    • Pfeffer, M.A.1    Mc Murray, J.J.2    Velasquez, E.J.3
  • 43
    • 0037031270 scopus 로고    scopus 로고
    • Microalbuminuria reduction with valsartan in patients with type 2 diabetes mellitus: A blood pressure-independent effect
    • Viberti GC, Wheeldon MN. Microalbuminuria reduction with valsartan in patients with type 2 diabetes mellitus: a blood pressure-independent effect. Circulation 2002;106:672-8.
    • (2002) Circulation , vol.106 , pp. 672-678
    • Viberti, G.C.1    Wheeldon, M.N.2
  • 44
    • 0030750293 scopus 로고    scopus 로고
    • Valsartan. A review of its pharmacology and therapeutic use in essential hypertension
    • Markham A, Goa KL. Valsartan. A review of its pharmacology and therapeutic use in essential hypertension. Drugs 1997;54:299-331.
    • (1997) Drugs , vol.54 , pp. 299-331
    • Markham, A.1    Goa, K.L.2
  • 45
    • 0038827402 scopus 로고    scopus 로고
    • Angiotensin II receptor blockers and cardiovascular outcomes: What does the future hold?
    • Weber AM. Angiotensin II receptor blockers and cardiovascular outcomes: what does the future hold? J Renin Ang Ald Syst 2003;4:62-73.
    • (2003) J Renin Ang Ald Syst , vol.4 , pp. 62-73
    • Weber, A.M.1
  • 46
    • 25844476905 scopus 로고    scopus 로고
    • Angiotensin receptor blockers: Therapeutic targets and cardiovascular protection
    • Ruilope LM, Agabite Rosei E, Bakris GL, et al. Angiotensin receptor blockers: therapeutic targets and cardiovascular protection. Blood Pressure 2005;14:196-209.
    • (2005) Blood Pressure , vol.14 , pp. 196-209
    • Ruilope, L.M.1    Agabite Rosei, E.2    Bakris, G.L.3


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