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Volumn 55, Issue 2, 2007, Pages 88-91

JAK2, the JAK2 V617F mutant and cytokine receptors

Author keywords

Erythropoietin; IGF1; JAK2; Thrombopoietin

Indexed keywords

CYTOKINE RECEPTOR; ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; JANUS KINASE; JANUS KINASE 1; JANUS KINASE 2; JANUS KINASE 2 V617F; JANUS KINASE 3; PEPTIDE; PHENYLALANYLGLUTAMYLARGINYLMETHIONINE; PROTEIN SH2; PROTEIN TYK2; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; STAT PROTEIN; THROMBOPOIETIN; THROMBOPOIETIN RECEPTOR; UNCLASSIFIED DRUG; JAK1 PROTEIN, HUMAN; JAK2 PROTEIN, HUMAN; JAK2 PROTEIN, MOUSE; MPL PROTEIN, HUMAN; PROTEIN KINASE TYK2; TYK2 PROTEIN, HUMAN;

EID: 33947128676     PISSN: 03698114     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.patbio.2006.06.003     Document Type: Article
Times cited : (23)

References (19)
  • 1
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C., Ugo V., Le Couedic J.P., Staerk J., Delhommeau F., Lacout C., et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 434 (2005) 1144
    • (2005) Nature , vol.434 , pp. 1144
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3    Staerk, J.4    Delhommeau, F.5    Lacout, C.6
  • 2
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter E.J., Scott L.M., Campbell P.J., East C., Fourouclas N., Swanton S., et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 365 (2005) 1054
    • (2005) Lancet , vol.365 , pp. 1054
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3    East, C.4    Fourouclas, N.5    Swanton, S.6
  • 4
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine R.L., Wadleigh M., Cools J., Ebert B.L., Wernig G., Huntly B.J., et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 7 (2005) 387
    • (2005) Cancer Cell , vol.7 , pp. 387
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3    Ebert, B.L.4    Wernig, G.5    Huntly, B.J.6
  • 5
    • 20744460045 scopus 로고    scopus 로고
    • Identification of an acquired JAK2 mutation in polycythemia vera
    • Zhao R., Xing S., Li Z., Fu X., Li Q., Krantz S.B., et al. Identification of an acquired JAK2 mutation in polycythemia vera. J. Biol. Chem. 280 (2005) 22788
    • (2005) J. Biol. Chem. , vol.280 , pp. 22788
    • Zhao, R.1    Xing, S.2    Li, Z.3    Fu, X.4    Li, Q.5    Krantz, S.B.6
  • 6
    • 25844462316 scopus 로고    scopus 로고
    • Constantinescu SN. Role of tyrosine kinases and phosphatases in Polycythemia Vera
    • Zhao Z.J., Krantz S.B., Vainchenker W., and Casadevall N. Constantinescu SN. Role of tyrosine kinases and phosphatases in Polycythemia Vera. Semin Hematol. 42 (2005) 221
    • (2005) Semin Hematol. , vol.42 , pp. 221
    • Zhao, Z.J.1    Krantz, S.B.2    Vainchenker, W.3    Casadevall, N.4
  • 7
    • 33646470398 scopus 로고    scopus 로고
    • A unique activating mutation in JAK2 is at the origin of Polycythemia Vera and allows a new classification of myeloproliferative diseases
    • Vainchenker W., and Constantinescu S.N. A unique activating mutation in JAK2 is at the origin of Polycythemia Vera and allows a new classification of myeloproliferative diseases. Hematology (Am Soc Hematol Educ Program) (2005) 195
    • (2005) Hematology (Am Soc Hematol Educ Program) , pp. 195
    • Vainchenker, W.1    Constantinescu, S.N.2
  • 8
    • 0035045092 scopus 로고    scopus 로고
    • Prediction of the structure of human Janus kinase 2 (JAK2) comprising the two carboxy-terminal domains reveals a mechanism for autoregulation
    • Lindauer K., Loerting T., Liedl K.R., and Kroemer R.T. Prediction of the structure of human Janus kinase 2 (JAK2) comprising the two carboxy-terminal domains reveals a mechanism for autoregulation. Protein Eng. 14 (2001) 27
    • (2001) Protein Eng. , vol.14 , pp. 27
    • Lindauer, K.1    Loerting, T.2    Liedl, K.R.3    Kroemer, R.T.4
  • 9
    • 0031017533 scopus 로고    scopus 로고
    • Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways
    • Luo H., Rose P., Barber D., Hanratty W.P., Lee S., Roberts T.M., et al. Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways. Mol. Cell. Biol. 17 (1997) 1562
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1562
    • Luo, H.1    Rose, P.2    Barber, D.3    Hanratty, W.P.4    Lee, S.5    Roberts, T.M.6
  • 10
    • 29644439240 scopus 로고    scopus 로고
    • JAK1 and Tyk2 activation by the homologous Polycythemia Vera JAK2 V617F mutation: cross-talk with IGF1 receptor
    • Staerk J., Kallin A., Demoulin J.-B., Vainchenker W., and Constantinescu S.N. JAK1 and Tyk2 activation by the homologous Polycythemia Vera JAK2 V617F mutation: cross-talk with IGF1 receptor. J. Biol. Chem. 280 (2005) 41893
    • (2005) J. Biol. Chem. , vol.280 , pp. 41893
    • Staerk, J.1    Kallin, A.2    Demoulin, J.-B.3    Vainchenker, W.4    Constantinescu, S.N.5
  • 11
    • 0035694582 scopus 로고    scopus 로고
    • The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor
    • Huang L.J., Constantinescu S.N., and Lodish H.F. The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor. Mol. Cell 8 (2001) 1327
    • (2001) Mol. Cell , vol.8 , pp. 1327
    • Huang, L.J.1    Constantinescu, S.N.2    Lodish, H.F.3
  • 12
    • 22844438893 scopus 로고    scopus 로고
    • Janus kinases affect thrombopoietin receptor cell surface localization and stability
    • Royer Y., Staerk J., Costuleanu M., Courtoy P.J., and Constantinescu S.N. Janus kinases affect thrombopoietin receptor cell surface localization and stability. J. Biol. Chem. 280 (2005) 27251
    • (2005) J. Biol. Chem. , vol.280 , pp. 27251
    • Royer, Y.1    Staerk, J.2    Costuleanu, M.3    Courtoy, P.J.4    Constantinescu, S.N.5
  • 13
    • 2642609475 scopus 로고    scopus 로고
    • Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera
    • Moliterno A.R., Hankins W.D., and Spivak J.L. Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera. N. Engl. J. Med. 338 (1998) 572
    • (1998) N. Engl. J. Med. , vol.338 , pp. 572
    • Moliterno, A.R.1    Hankins, W.D.2    Spivak, J.L.3
  • 14
    • 0032830543 scopus 로고    scopus 로고
    • Posttranslational processing of the thrombopoietin receptor is impaired in polycythemia vera
    • Moliterno A.R., and Spivak J.L. Posttranslational processing of the thrombopoietin receptor is impaired in polycythemia vera. Blood 94 (1999) 2555
    • (1999) Blood , vol.94 , pp. 2555
    • Moliterno, A.R.1    Spivak, J.L.2
  • 15
    • 30044437118 scopus 로고    scopus 로고
    • Expression of a type I cytokine receptor is required for JAK2V617F-mediated transformation and for constitutive JAK-STAT activation
    • Lu X., Levine R., Tong W., Wernig G., Pikman Y., Zarnegar S., et al. Expression of a type I cytokine receptor is required for JAK2V617F-mediated transformation and for constitutive JAK-STAT activation. Proc. Natl. Acad. Sci. USA 102 (2005) 18962
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 18962
    • Lu, X.1    Levine, R.2    Tong, W.3    Wernig, G.4    Pikman, Y.5    Zarnegar, S.6
  • 16
    • 0035836645 scopus 로고    scopus 로고
    • Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain
    • Constantinescu S.N., Keren T., Socolovsky M., Nam H., Henis Y.I., and Lodish H.F. Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain. Proc. Natl. Acad. Sci. USA 98 (2001) 4379
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 4379
    • Constantinescu, S.N.1    Keren, T.2    Socolovsky, M.3    Nam, H.4    Henis, Y.I.5    Lodish, H.F.6
  • 17
    • 0344413478 scopus 로고    scopus 로고
    • Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer
    • Seubert N., Royer Y., Staerk J., Kubatzky K.F., Moucadel V., Krishnakumar S., et al. Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer. Mol. Cell 12 (2003) 1239
    • (2003) Mol. Cell , vol.12 , pp. 1239
    • Seubert, N.1    Royer, Y.2    Staerk, J.3    Kubatzky, K.F.4    Moucadel, V.5    Krishnakumar, S.6
  • 18
    • 0028045069 scopus 로고
    • Circulating erythroid progenitors in polycythemia vera are hypersensitive to insulin-like growth factor-1 in vitro: studies in an improved serum-free medium
    • Correa P.N., Eskinazi D., and Axelrad A.A. Circulating erythroid progenitors in polycythemia vera are hypersensitive to insulin-like growth factor-1 in vitro: studies in an improved serum-free medium. Blood 83 (1994) 99
    • (1994) Blood , vol.83 , pp. 99
    • Correa, P.N.1    Eskinazi, D.2    Axelrad, A.A.3
  • 19
    • 0029166875 scopus 로고
    • Increased basal and induced tyrosine phosphorylation of the insulin-like growth factor I receptor beta subunit in circulating mononuclear cells of patients with polycythemia vera
    • Mirza A.M., Correa P.N., and Axelrad A.A. Increased basal and induced tyrosine phosphorylation of the insulin-like growth factor I receptor beta subunit in circulating mononuclear cells of patients with polycythemia vera. Blood 86 (1995) 877
    • (1995) Blood , vol.86 , pp. 877
    • Mirza, A.M.1    Correa, P.N.2    Axelrad, A.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.