JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: Cross-talk with IGF1 receptor

Journal of Biological Chemistry

Volumn 280, Issue 51, 2005, Pages 41893-41899

  Staerk, Judith ^a,b   Kallin, Anders ^b   Demoulin, Jean Baptiste ^b   Vainchenker, William ^c   Constantinescu, Stefan N ^a,b  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Belgium)

^b DE DUVE INSTITUTE   (Belgium)

^c INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOELECTRIC POTENTIALS; CELL CULTURE; CROSSTALK; GENES; GROWTH KINETICS; IMMUNOLOGY; MUTAGENESIS; TUMORS;

FIBROSARCOMA CELLS; HOMOLOGOUS POLYCYTHEMIA VERA; PROLIFERATION; SOMATIC MUTATION;

ENZYMES;

CYTOKINE; JANUS KINASE 1; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MUTANT PROTEIN; PROTEIN KINASE B; PROTEIN TYK2; PROTEIN TYROSINE KINASE; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; STAT3 PROTEIN; STAT5 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOIMMUNE DISEASE; CANCER; CELL GROWTH; CELL PROLIFERATION; CELL SELECTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEFICIENCY; ENZYME INDUCTION; ERYTHROID PRECURSOR CELL; GENE MUTATION; GENE SEQUENCE; GENETIC CONSERVATION; HUMAN; HUMAN CELL; POLYCYTHEMIA VERA; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOMATIC MUTATION;

CELL LINE, TUMOR; ENZYME ACTIVATION; HUMANS; JANUS KINASE 1; LIGANDS; MUTATION; POLYCYTHEMIA VERA; PROTEIN-TYROSINE KINASES; RECEPTOR CROSS-TALK; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TYK2 KINASE;

EID: 29644439240     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C500358200     Document Type: Article

References (41)

1. James, C., Ugo, V., Le Couedic, J. P., Staerk, J., Delhommeau, F., Lacout, C., Garcon, L., Raslova, H., Berger, R., Bennaceur-Griscelli, A., Villeval, J. L., Constantinescu, S. N., Casadevall, N., and Vainchenker, W. (2005) Nature 434, 1144-1148
2. Baxter, E. J., Scott, L. M., Campbell, P. J., East, C., Fourouclas, N., Swanton, S., Vassiliou, G. S., Bench, A. J., Boyd, E. M., Curtin, N., Scott, M. A., Erber, W. N., and Green, A. R. (2005) Lancet 365, 1054-1061
3. Levine, R. L., Wadleigh, M., Cools, J., Ebert, B. L., Wernig, G., Huntly, B. J., Boggon, T. J., Wlodarska, I., Clark, J. J., Moore, S., Adelsperger, J., Koo, S., Lee, J. C., Gabriel, S., Mercher, T., D'Andrea, A., Fronting, S., Dohner, K., Marynen, P., Vandenberghe, P., Mesa, R. A., Tefferi, A., Griffin, J. D., Eck, M. J., Sellers, W. R., Meyerson, M., Golub, T. R., Lee, S. J., and Gilliland, D. G. (2005) Cancer Cell 7, 387-397
4. Kralovics, R., Passamonti, F., Buser, A. S., Teo, S. S., Tiedt, R., Passweg, J. R., Tichelli, A., Cazzola, M., and Skoda, R. C. (2005) N. Engl. J. Med. 352, 1779-1790
5. Zhao, R., Xing, S., Li, Z., Fu, X., Li, Q., Krantz, S. B., and Zhao, Z. J. (2005) J. Biol. Chem. 280, 22788-22792
6. Vainchenker, W., and Constantinescu, S. N. (2005) Hematology (Am. Soc. Hematol. Educ. Program), in press
7. Zhao, Z. J., Krantz, S. B., Vainchenker, W., Casadevall, N., and Constantinescu, S. N. (2005) Semin. Hematol. 42, 221-229
8. Yamaoka, K., Saharinen, P., Pesu, M., Holt, V. E., 3rd, Silvennoinen, O., and O'Shea, J. J. (2004) Genome Biol. 5, 253
9. Luo, H., Rose, P., Barber, D., Hanratty, W. P., Lee, S., Roberts, T. M., D'Andrea, A. D., and Dearolf, C. R. (1997) Mol. Cell. Biol. 17, 1562-1571
10. Chen, M., Cheng, A., Candotti, F., Zhou, Y. J., Hymel, A., Fasth, A., Notarangelo, L. D., and O'Shea, J. J. (2000) Mol. Cell. Biol. 20, 947-956
11. Saharinen, P., Takaluoma, K., and Silvennoinen, O. (2000) Mol. Cell. Biol. 20, 3387-3395
12. Feener, E. P., Rosario, F., Dunn, S. L., Stancheva, Z., and Myers, M. G., Jr. (2004) Mol. Cell. Biol. 24, 4968-4978
13. Argetsinger, L. S., Kouadio, J. L., Steen, H., Stensballe, A., Jensen, O. N., and Carter-Su, C. (2004) Mol. Cell. Biol. 24, 4955-4967
14. Kurzer, J. H., Argetsinger, L. S., Zhou, Y. J., Kouadio, J. L., O'Shea, J. J., and Carter-Su, C. (2004) Mol. Cell. Biol. 24, 4557-4570
15. Feng, J., Witthuhn, B. A., Matsuda, T., Kohlhuber, F., Kerr, I. M., and Ihle, J. N. (1997) Mol. Cell. Biol. 17, 2497-2501
16. Velazquez, L., Mogensen, K. E., Barbieri, G., Fellous, M., Uze, G., and Pellegrini, S. (1995) J. Biol. Chem. 270, 3327-3334
17. Yeh, T. C., Dondi, E., Uze, G., and Pellegrini, S. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 8991-8996
18. Correa, P. N., Eskinazi, D., and Axelrad, A. A. (1994) Blood 83, 99-112
19. Mirza, A. M., Correa, P. N., and Axelrad, A. A. (1995) Blood 86, 877-882
20. Mirza, A. M., Ezzat, S., and Axelrad, A. A. (1997) Blood 89, 1862-1869
21. Gauzzi, M. C., Velazquez, L., McKendry, R., Mogensen, K., E., Fellous, M., and Pellegrini, S. (1996) J. Biol. Chem. 271, 20494-20500
22. Liu, X., Constantinescu, S. N., Sun, Y., Bogan, J. S., Hirsch, D., Weinberg, R. A., and Lodish, H. F. (2000) Anal. Biochem. 280, 20-28
23. Seubert, N., Royer, Y., Staerk, J., Kubatzky, K. F., Moucadel, V., Krishnakumar, S., Smith, S. O., and Constantinescu, S. N. (2003) Mol. Cell 12, 1239-1250
24. Muller, M., Briscoe, J., Laxton, C., Guschin, D., Ziemiecki, A., Silvennoinen, O., Harpur, A. G., Barbieri, G., Witthuhn, B, A., Schindler, C., Pellegrini, S., Wilks, A. F., Ihle, J. N., Stark, G. R., and Kerr, I. M. (1993) Nature 366, 129-135
25. Pellegrini, S., John, J., Shearer, M., Kerr, I. M., and Stark, G. R. (1989) Mol. Cell. Biol. 9, 4605-4612
26. Velazquez, L., Fellous, M., Stark, G. R., and Pellegrini, S. (1992) Cell 70, 313-322
27. Dumoutier, L., Van Roost, E., Colau, D., and Renauld, J. C. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 10144-10149
28. Eyckerman, S., Waelput, W., Verhee, A., Broekaert, D., Vandekerckhove, J., and Tavernier, J. (1999) Eur. Cytokine Netw. 10, 549-556
29. Sotiropoulos, A., Moutoussamy, S., Binart, N., Kelly, P. A., and Finidori, J. (1995) FEBS Lett. 369, 169-172
30. Mohammadi, M., Schlessinger, J., and Hubbard, S. R. (1996) Cell 86, 577-587
31. Lindauer, K., Loerting, T., Liedl, K. R., and Kroemer, R. T. (2001) Protein Eng. 14, 27-37
32. Darnell, J. E., Jr., Kerr, I. M., and Stark, G. R. (1994) Science 264, 1415-1421
33. Moliterno, A. R., Hankins, W. D., and Spivak, J. L. (1998) N. Engl. J. Med. 338, 572-580
34. Moliterno, A. R., and Spivak, J. L. (1999) Blood 94, 2555-2561
35. Callus, B. A., and Mathey-Prevot, B. (1998) Blood 91, 3182-3192
36. Frank, S. J., Yi, W., Zhao, Y., Goldsmith, J. F., Gilliland, G., Jiang, J., Sakai, I., and Kraft, A. S. (1995) J. Biol. Chem. 270, 14776-14785
37. Chang, M. S., Chang, G. D., Leu, J. H., Huang, F. L., Chou, C. K., Huang, C. J., and Lo, T. B. (1996) DNA Cell Biol. 15, 827-844
38. Zong, C. S., Chan, J., Levy, D. E., Horvath, C., Sadowski, H. B., and Wang, L. H. (2000) J. Biol. Chem. 275, 15099-15105
39. Gual, P., Baron, V., Lequoy, V., and Van Obberghen, E. (1998) Endocrinology 139, 884-893
40. de la Chapelle, A., Traskelin, A.-L., and Juvonen, E. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 4495-4499
41. Damen, J. E., Krosl, J., Morrison, D., Pelech, S., and Krystal, G. (1998) Blood 92, 425-433