Accessory proteins assist exonuclease-deficient bacteriophage T4 DNA polymerase in replicating past an abasic site

Biochemical Journal

Volumn 402, Issue 2, 2007, Pages 321-329

  Blanca, Giuseppina ^a   Delagoutte, Emmanuelle ^b   Tanguy Le Gac, Nicolas ^a   Johnson, Neil P ^a   Baldacci, Giuseppe ^b   Villani, Giuseppe ^a  

^a CNRS   (France)

^b INSTITUT CURIE   (France)

Author keywords

Abasic site; DNA minicircle; Exonuclease deficient polymerase; Replication complex; T4 DNA polymerase; Translesion DNA synthesis (TLS)

Indexed keywords

ABASIC SITES; DNA MINICIRCLES; EXONUCLEASE DEFICIENT POLYMERASE; REPLICATION COMPLEX; T4 DNA POLYMERASE; TRANSLESION DNA SYNTHESIS (TLS);

BIOCHEMICAL ENGINEERING; CATALYST ACTIVITY; DNA SEQUENCES; NUCLEOTIDES; PROTEINS; SYNTHESIS (CHEMICAL);

ENZYME KINETICS;

3' 5' EXONUCLEASE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA POLYMERASE; EXONUCLEASE; NUCLEOTIDE; UNCLASSIFIED DRUG; DNA DIRECTED DNA POLYMERASE; VIRUS DNA;

ARTICLE; BACTERIAL REPRODUCTION; BACTERIOPHAGE T4; CONTROLLED STUDY; DNA DAMAGE; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME MECHANISM; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; STIMULUS RESPONSE; WILD TYPE; DNA REPLICATION; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

BACTERIOPHAGE T4; BASE SEQUENCE; DNA REPLICATION; DNA, VIRAL; DNA-DIRECTED DNA POLYMERASE; EXONUCLEASES; MOLECULAR SEQUENCE DATA; NUCLEOTIDES; SUBSTRATE SPECIFICITY; TEMPLATES, GENETIC;

EID: 33847738957     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060898     Document Type: Article

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