-
1
-
-
21244462421
-
Adjuvant therapy for colon cancer - the pace quickens
-
Allegra C, Sargent DJ (2005) Adjuvant therapy for colon cancer - the pace quickens. N Engl J Med 352: 2746-2748
-
(2005)
N Engl J Med
, vol.352
, pp. 2746-2748
-
-
Allegra, C.1
Sargent, D.J.2
-
2
-
-
0003809054
-
-
American Joint Committee on Cancer , 6th edn, pp, New York, NY: Springer
-
American Joint Committee on Cancer (2002) AJCC Cancer Staging Manual. 6th edn, pp 113-124. New York, NY: Springer
-
(2002)
AJCC Cancer Staging Manual
, pp. 113-124
-
-
-
3
-
-
2542615200
-
Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer
-
Andre T, Boni C, Mounedji-Boudiaf L, Navarro M, Tabernero J, Hickish T, Topham C, Zaninelli M, Clingan P, Bridgewater J, Tabah-Fisch I, de Gramont A (2004) Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med 350: 2343-2351
-
(2004)
N Engl J Med
, vol.350
, pp. 2343-2351
-
-
Andre, T.1
Boni, C.2
Mounedji-Boudiaf, L.3
Navarro, M.4
Tabernero, J.5
Hickish, T.6
Topham, C.7
Zaninelli, M.8
Clingan, P.9
Bridgewater, J.10
Tabah-Fisch, I.11
de Gramont, A.12
-
4
-
-
0042887580
-
Semimonthly versus monthly regimen of fluorouracil and leucovorin administered for 24 or 36 weeks as adjuvant therapy in stage II and III colon cancer: Results of a randomized trial
-
Andre T, Colin P, Louvet C, Gamelin E, Bouche O, Achille E, Colbert N, Boaziz C, Piedbois P, Tubiana-Mathieu N, Boutan-Laroze A, Flesch M, Buyse M, de Gramont A (2003) Semimonthly versus monthly regimen of fluorouracil and leucovorin administered for 24 or 36 weeks as adjuvant therapy in stage II and III colon cancer: results of a randomized trial. J Clin Oncol 21: 2896-2903
-
(2003)
J Clin Oncol
, vol.21
, pp. 2896-2903
-
-
Andre, T.1
Colin, P.2
Louvet, C.3
Gamelin, E.4
Bouche, O.5
Achille, E.6
Colbert, N.7
Boaziz, C.8
Piedbois, P.9
Tubiana-Mathieu, N.10
Boutan-Laroze, A.11
Flesch, M.12
Buyse, M.13
de Gramont, A.14
-
6
-
-
0036727089
-
Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
-
Carmichael J, Popiela T, Radstone D, Falk S, Borner M, Oza A, Skovsgaard T, Munier S, Martin C (2002) Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 20: 3617-3627
-
(2002)
J Clin Oncol
, vol.20
, pp. 3617-3627
-
-
Carmichael, J.1
Popiela, T.2
Radstone, D.3
Falk, S.4
Borner, M.5
Oza, A.6
Skovsgaard, T.7
Munier, S.8
Martin, C.9
-
7
-
-
14744273146
-
Differences in toxicity between men and women treated with 5-fluorouracil therapy for colorectal carcinoma
-
Chansky K, Benedetti J, Macdonald JS (2005) Differences in toxicity between men and women treated with 5-fluorouracil therapy for colorectal carcinoma. Cancer 103: 1165-1171
-
(2005)
Cancer
, vol.103
, pp. 1165-1171
-
-
Chansky, K.1
Benedetti, J.2
Macdonald, J.S.3
-
8
-
-
33646443078
-
Completion of therapy by Medicare patients with stage III colon cancer
-
Dobie SA, Baldwin LM, Dominitz JA, Matthews B, Billingsley K, Barlow W (2006) Completion of therapy by Medicare patients with stage III colon cancer. J Natl Cancer Inst 98: 610-619
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 610-619
-
-
Dobie, S.A.1
Baldwin, L.M.2
Dominitz, J.A.3
Matthews, B.4
Billingsley, K.5
Barlow, W.6
-
9
-
-
0036731818
-
Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
-
Douillard JY, Hoff PM, Skillings JR, Eisenberg P, Davidson N, Harper P, Vincent MD, Lembersky BC, Thompson S, Maniero A, Benner SE (2002) Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 20: 3605-3616
-
(2002)
J Clin Oncol
, vol.20
, pp. 3605-3616
-
-
Douillard, J.Y.1
Hoff, P.M.2
Skillings, J.R.3
Eisenberg, P.4
Davidson, N.5
Harper, P.6
Vincent, M.D.7
Lembersky, B.C.8
Thompson, S.9
Maniero, A.10
Benner, S.E.11
-
10
-
-
33646110275
-
Chemotherapy for colorectal cancer
-
Goyle S, Maraveyas A (2005) Chemotherapy for colorectal cancer. Dig Surg 22: 401-414
-
(2005)
Dig Surg
, vol.22
, pp. 401-414
-
-
Goyle, S.1
Maraveyas, A.2
-
11
-
-
0036789418
-
Effectiveness of adjuvant fluorouracil in clinical practice: A population-based cohort study of elderly patients with stage III colon cancer
-
Iwashyna TJ, Lamont EB (2002) Effectiveness of adjuvant fluorouracil in clinical practice: a population-based cohort study of elderly patients with stage III colon cancer. J Clin Oncol 20: 3992-3998
-
(2002)
J Clin Oncol
, vol.20
, pp. 3992-3998
-
-
Iwashyna, T.J.1
Lamont, E.B.2
-
12
-
-
28844482345
-
Adjuvant chemotherapy for stage III colon cancer: Implications of race/ethnicity, age, and differentiation
-
Jessup JM, Stewart A, Greene FL, Minsky BD (2005) Adjuvant chemotherapy for stage III colon cancer: implications of race/ethnicity, age, and differentiation. JAMA 294: 2703-2711
-
(2005)
JAMA
, vol.294
, pp. 2703-2711
-
-
Jessup, J.M.1
Stewart, A.2
Greene, F.L.3
Minsky, B.D.4
-
13
-
-
0035793817
-
5-fluorouracil steady state pharmacokinetics and outcome in patients receiving protracted venous infusion for advanced colorectal cancer
-
Jodrell DI, Stewart M, Aird R, Knowles G, Bowman A, Wall L, McLean C (2001) 5-fluorouracil steady state pharmacokinetics and outcome in patients receiving protracted venous infusion for advanced colorectal cancer. Br J Cancer 84: 600-603
-
(2001)
Br J Cancer
, vol.84
, pp. 600-603
-
-
Jodrell, D.I.1
Stewart, M.2
Aird, R.3
Knowles, G.4
Bowman, A.5
Wall, L.6
McLean, C.7
-
14
-
-
5344252377
-
Sixty-day all-cause mortality rates in patients treated for gastrointestinal cancers, in randomised trials, at the Royal Marsden Hospital
-
Katopodis O, Ross P, Norman AR, Oates J, Cunningham D (2004) Sixty-day all-cause mortality rates in patients treated for gastrointestinal cancers, in randomised trials, at the Royal Marsden Hospital. Eur J Cancer 40: 2230-2236
-
(2004)
Eur J Cancer
, vol.40
, pp. 2230-2236
-
-
Katopodis, O.1
Ross, P.2
Norman, A.R.3
Oates, J.4
Cunningham, D.5
-
15
-
-
0346103808
-
The folate pool in colorectal cancers is associated with DNA hypermethylation and with a polymorphism in methylenetetrahydrofolate reductase
-
Kawakami K, Ruszkiewicz A, Bennett G, Moore J, Watanabe G, Iacopetta B (2003) The folate pool in colorectal cancers is associated with DNA hypermethylation and with a polymorphism in methylenetetrahydrofolate reductase. Clin Cancer Res 9: 5860-5865
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5860-5865
-
-
Kawakami, K.1
Ruszkiewicz, A.2
Bennett, G.3
Moore, J.4
Watanabe, G.5
Iacopetta, B.6
-
16
-
-
0345596364
-
Toxicity of fluorouracil in patients with advanced colorectal cancer: Effect of administration schedule and prognostic factors
-
Meta-analysis Group in Cancer
-
Meta-analysis Group in Cancer (1998) Toxicity of fluorouracil in patients with advanced colorectal cancer: effect of administration schedule and prognostic factors. J Clin Oncol 16: 3537-3541
-
(1998)
J Clin Oncol
, vol.16
, pp. 3537-3541
-
-
-
17
-
-
0026636184
-
Influence of sex and age on fluorouracil clearance
-
Milano G, Etienne MC, Cassuto-Viguier E, Thyss A, Santini J, Frenay M, Renee N, Schneider M, Demard F (1992) Influence of sex and age on fluorouracil clearance. J Clin Oncol 10: 1171-1175
-
(1992)
J Clin Oncol
, vol.10
, pp. 1171-1175
-
-
Milano, G.1
Etienne, M.C.2
Cassuto-Viguier, E.3
Thyss, A.4
Santini, J.5
Frenay, M.6
Renee, N.7
Schneider, M.8
Demard, F.9
-
18
-
-
0028357629
-
Relationship between fluorouracil systemic exposure and tumor response and patient survival
-
Milano G, Etienne MC, Renee N, Thyss A, Schneider M, Ramaioli A, Demard F (1994) Relationship between fluorouracil systemic exposure and tumor response and patient survival. J Clin Oncol 12: 1291-1295
-
(1994)
J Clin Oncol
, vol.12
, pp. 1291-1295
-
-
Milano, G.1
Etienne, M.C.2
Renee, N.3
Thyss, A.4
Schneider, M.5
Ramaioli, A.6
Demard, F.7
-
19
-
-
0025060806
-
Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma
-
Moertel CG, Fleming TR, Macdonald JS, Haller DG, Laurie JA, Goodman PJ, Ungerleider JS, Emerson WA, Tormey DC, Glick JH, Veeder MH, Mailliard JA (1990) Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma. N Engl J Med 322: 352-358
-
(1990)
N Engl J Med
, vol.322
, pp. 352-358
-
-
Moertel, C.G.1
Fleming, T.R.2
Macdonald, J.S.3
Haller, D.G.4
Laurie, J.A.5
Goodman, P.J.6
Ungerleider, J.S.7
Emerson, W.A.8
Tormey, D.C.9
Glick, J.H.10
Veeder, M.H.11
Mailliard, J.A.12
-
20
-
-
33744831506
-
Duration of adjuvant chemotherapy for colon cancer and survival among the elderly
-
Neugut AI, Matasar M, Wang X, McBride R, Jacobson JS, Tsai WY, Grann VR, Hershman DL (2006) Duration of adjuvant chemotherapy for colon cancer and survival among the elderly. J Clin Oncol 24: 2368-2375
-
(2006)
J Clin Oncol
, vol.24
, pp. 2368-2375
-
-
Neugut, A.I.1
Matasar, M.2
Wang, X.3
McBride, R.4
Jacobson, J.S.5
Tsai, W.Y.6
Grann, V.R.7
Hershman, D.L.8
-
21
-
-
84944371744
-
-
NIH consensus conference (1990) Adjuvant therapy for patients with colon and rectal cancer. JAMA 264: 1444-1450
-
NIH consensus conference (1990) Adjuvant therapy for patients with colon and rectal cancer. JAMA 264: 1444-1450
-
-
-
-
22
-
-
33645752308
-
Current status of adjuvant therapy for colorectal cancer
-
O'Connell MJ (2004) Current status of adjuvant therapy for colorectal cancer. Oncology 18: 751-755
-
(2004)
Oncology
, vol.18
, pp. 751-755
-
-
O'Connell, M.J.1
-
23
-
-
0031022988
-
Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer
-
O'Connell MJ, Mailliard JA, Kahn MJ, Macdonald JS, Haller DG, Mayer RJ, Wieand HS (1997) Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer. J Clin Oncol 15: 246-250
-
(1997)
J Clin Oncol
, vol.15
, pp. 246-250
-
-
O'Connell, M.J.1
Mailliard, J.A.2
Kahn, M.J.3
Macdonald, J.S.4
Haller, D.G.5
Mayer, R.J.6
Wieand, H.S.7
-
24
-
-
0024164649
-
Fluorouracil: Biochemistry and pharmacology
-
Pinedo HM, Peters GF (1988) Fluorouracil: biochemistry and pharmacology. J Clin Oncol 6: 1653-1664
-
(1988)
J Clin Oncol
, vol.6
, pp. 1653-1664
-
-
Pinedo, H.M.1
Peters, G.F.2
-
25
-
-
0032792959
-
Adjuvant or palliative chemotherapy for colorectal cancer in patients 70 years or older
-
Popescu RA, Norman A, Ross PJ, Parikh B, Cunningham D (1999) Adjuvant or palliative chemotherapy for colorectal cancer in patients 70 years or older. J Clin Oncol 17: 2412-2418
-
(1999)
J Clin Oncol
, vol.17
, pp. 2412-2418
-
-
Popescu, R.A.1
Norman, A.2
Ross, P.J.3
Parikh, B.4
Cunningham, D.5
-
26
-
-
15744377355
-
Phase III Southwest Oncology Group 9415/Intergroup 0153 randomized trial of fluorouracil, leucovorin, and levamisole versus fluorouracil continuous infusion and levamisole for adjuvant treatment of stage III and high-risk stage II colon cancer
-
Poplin EA, Benedetti JK, Estes NC, Haller DG, Mayer RJ, Goldberg RM, Weiss GR, Rivkin SE, Macdonald JS (2005) Phase III Southwest Oncology Group 9415/Intergroup 0153 randomized trial of fluorouracil, leucovorin, and levamisole versus fluorouracil continuous infusion and levamisole for adjuvant treatment of stage III and high-risk stage II colon cancer. J Clin Oncol 23: 1819-1825
-
(2005)
J Clin Oncol
, vol.23
, pp. 1819-1825
-
-
Poplin, E.A.1
Benedetti, J.K.2
Estes, N.C.3
Haller, D.G.4
Mayer, R.J.5
Goldberg, R.M.6
Weiss, G.R.7
Rivkin, S.E.8
Macdonald, J.S.9
-
27
-
-
0038575246
-
Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer
-
Saini A, Norman AR, Cunningham D, Chau I, Hill M, Tait D, Hickish T, Iveson T, Lofts F, Jodrell D, Ross PJ, Oates J (2003) Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer. Br J Cancer 88: 1859-1865
-
(2003)
Br J Cancer
, vol.88
, pp. 1859-1865
-
-
Saini, A.1
Norman, A.R.2
Cunningham, D.3
Chau, I.4
Hill, M.5
Tait, D.6
Hickish, T.7
Iveson, T.8
Lofts, F.9
Jodrell, D.10
Ross, P.J.11
Oates, J.12
-
28
-
-
33847722573
-
Phase III trial of capecitabine plus oxaliplatin as adjuvant therapy for stage III colon cancer: A planned safety analysis in 1, 864 patients
-
Schmoll HJ, Cartwright T, Tabernero J, Nowacki MP, Figer A, Maroun J, Price T, Lim R, Van Cutsem E, Park YS, McKendrick J, Topham C, Soler-Gonzalez G, de Braud F, Hill M, Sirzen F, Haller DG (2007) Phase III trial of capecitabine plus oxaliplatin as adjuvant therapy for stage III colon cancer: a planned safety analysis in 1, 864 patients. J Clin Oncol 25: 102-1099
-
(2007)
J Clin Oncol
, vol.25
, pp. 102-1099
-
-
Schmoll, H.J.1
Cartwright, T.2
Tabernero, J.3
Nowacki, M.P.4
Figer, A.5
Maroun, J.6
Price, T.7
Lim, R.8
Van Cutsem, E.9
Park, Y.S.10
McKendrick, J.11
Topham, C.12
Soler-Gonzalez, G.13
de Braud, F.14
Hill, M.15
Sirzen, F.16
Haller, D.G.17
-
29
-
-
0037087563
-
Women experience greater toxicity with fluorouracil-based chemotherapy for colorectal cancer
-
Sloan JA, Goldberg RM, Sargent DJ, Vargas-Chanes D, Nair S, Cha SS, Novotny PJ, Poon MA, O'Connell MJ, Loprinzi CL (2002) Women experience greater toxicity with fluorouracil-based chemotherapy for colorectal cancer. J Clin Oncol 20: 1491-1498
-
(2002)
J Clin Oncol
, vol.20
, pp. 1491-1498
-
-
Sloan, J.A.1
Goldberg, R.M.2
Sargent, D.J.3
Vargas-Chanes, D.4
Nair, S.5
Cha, S.S.6
Novotny, P.J.7
Poon, M.A.8
O'Connell, M.J.9
Loprinzi, C.L.10
-
30
-
-
0037022820
-
Survival associated with 5-fluorouracil-based adjuvant chemotherapy among elderly patients with node-positive colon cancer
-
Sundararajan V, Mitra N, Jacobson JS, Grann VR, Heitjan DF, Neugut AI (2002) Survival associated with 5-fluorouracil-based adjuvant chemotherapy among elderly patients with node-positive colon cancer. Ann Intern Med 136: 349-357
-
(2002)
Ann Intern Med
, vol.136
, pp. 349-357
-
-
Sundararajan, V.1
Mitra, N.2
Jacobson, J.S.3
Grann, V.R.4
Heitjan, D.F.5
Neugut, A.I.6
-
31
-
-
0038793712
-
Analysis of the time course and prognostic factors determining toxicity due to infused fluorouracil
-
Tebbutt NC, Norman AR, Cunningham D, Allen M, Chau I, Oates J, Hill M (2000) Analysis of the time course and prognostic factors determining toxicity due to infused fluorouracil. Br J Cancer 88: 1510-1515
-
(2000)
Br J Cancer
, vol.88
, pp. 1510-1515
-
-
Tebbutt, N.C.1
Norman, A.R.2
Cunningham, D.3
Allen, M.4
Chau, I.5
Oates, J.6
Hill, M.7
-
32
-
-
21244497388
-
Capecitabine as adjuvant treatment for stage III colon cancer
-
Twelves C, Wong A, Nowacki MP, Abt M, Burris III H, Carrato A, Cassidy J, Cervantes A, Fagerberg J, Georgoulias V, Husseini F, Jodrell D, Koralewski P, Kroning H, Maroun J, Marschner N, McKendrick J, Pawlicki M, Rosso R, Schuller J, Seitz JF, Stabuc B, Tujakowski J, Van Hazel G, Zaluski J, Scheithauer W (2005) Capecitabine as adjuvant treatment for stage III colon cancer. N Engl J Med 352: 2696-2704
-
(2005)
N Engl J Med
, vol.352
, pp. 2696-2704
-
-
Twelves, C.1
Wong, A.2
Nowacki, M.P.3
Abt, M.4
Burris III, H.5
Carrato, A.6
Cassidy, J.7
Cervantes, A.8
Fagerberg, J.9
Georgoulias, V.10
Husseini, F.11
Jodrell, D.12
Koralewski, P.13
Kroning, H.14
Maroun, J.15
Marschner, N.16
McKendrick, J.17
Pawlicki, M.18
Rosso, R.19
Schuller, J.20
Seitz, J.F.21
Stabuc, B.22
Tujakowski, J.23
Van Hazel, G.24
Zaluski, J.25
Scheithauer, W.26
more..
-
33
-
-
0041524111
-
CpG island methylator phenotype is an independent predictor of survival benefit from 5-fluorouracil in stage III colorectal cancer
-
Van Rijnsoever M, Elsaleh H, Joseph D, McCaul K, Iacopetta B (2003) CpG island methylator phenotype is an independent predictor of survival benefit from 5-fluorouracil in stage III colorectal cancer. Clin Cancer Res 9: 2898-2903
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2898-2903
-
-
Van Rijnsoever, M.1
Elsaleh, H.2
Joseph, D.3
McCaul, K.4
Iacopetta, B.5
-
34
-
-
0142087630
-
Adverse prognostic effect of methylation in colorectal cancer is reversed by microsatellite instability
-
Ward RL, Cheong K, Ku SL, Meagher A, O'Connor T, Hawkins NJ (2003) Adverse prognostic effect of methylation in colorectal cancer is reversed by microsatellite instability. J Clin Oncol 21: 3729-3736
-
(2003)
J Clin Oncol
, vol.21
, pp. 3729-3736
-
-
Ward, R.L.1
Cheong, K.2
Ku, S.L.3
Meagher, A.4
O'Connor, T.5
Hawkins, N.J.6
-
35
-
-
0027436244
-
The benefit of leucovorin-modulated fluorouracil as postoperative adjuvant therapy for primary colon cancer: Results from National Surgical Adjuvant Breast and Bowel Project protocol C-03
-
Wolmark N, Rockette H, Fisher B, Wickerham DL, Redmond C, Fisher ER, Jones J, Mamounas EP, Ore L, Petrelli NJ, Spurr CL, Dimitrov N, Romond EH, Sutherland CM, Kardinal CG, Defusco PA, Jochimsen P (1993) The benefit of leucovorin-modulated fluorouracil as postoperative adjuvant therapy for primary colon cancer: results from National Surgical Adjuvant Breast and Bowel Project protocol C-03. J Clin Oncol 11: 1879-1887
-
(1993)
J Clin Oncol
, vol.11
, pp. 1879-1887
-
-
Wolmark, N.1
Rockette, H.2
Fisher, B.3
Wickerham, D.L.4
Redmond, C.5
Fisher, E.R.6
Jones, J.7
Mamounas, E.P.8
Ore, L.9
Petrelli, N.J.10
Spurr, C.L.11
Dimitrov, N.12
Romond, E.H.13
Sutherland, C.M.14
Kardinal, C.G.15
Defusco, P.A.16
Jochimsen, P.17
-
36
-
-
0032211354
-
Haematological and nonhaematological toxicity after 5-fluorouracil and leucovorin in patients with advanced colorectal cancer is significantly associated with gender, increasing age and cycle number. Tomudex International Study Group
-
Zalcberg J, Kerr D, Seymour L, Palmer M (1998) Haematological and nonhaematological toxicity after 5-fluorouracil and leucovorin in patients with advanced colorectal cancer is significantly associated with gender, increasing age and cycle number. Tomudex International Study Group. Eur J Cancer 34: 1871-1875
-
(1998)
Eur J Cancer
, vol.34
, pp. 1871-1875
-
-
Zalcberg, J.1
Kerr, D.2
Seymour, L.3
Palmer, M.4
|